Table of contents:
- Functions & Usage
- What is the drug Propafenone used for?
- How do you use the drug Propafenone?
- How to store Propafenone?
- Precautions & Warnings
- What should be considered before using the drug Propafenone?
- Is the drug Propafenone safe for pregnant and lactating women?
- Side effects
- What are the possible side effects of Propafenone?
- Drug Interactions
- What drugs can interfere with the drug Propafenone?
- Can certain foods and drinks interfere with the work of the drug Propafenone?
- What health conditions can interfere with the performance of the drug Propafenone?
- Dose
- What is the dose of the drug Propafenone for adults?
- What is the dosage of the drug Propafenone for children?
- In what dosages and preparations is Propafenone available?
- What to do in an emergency or overdose?
- What should I do if I forget to take medicine or forget to take medicine?
Functions & Usage
What is the drug Propafenone used for?
Propafenone is a drug to help prevent serious types of arrhythmias that may be fatal, for example paroxysmal supraventricular tachycardia and atrial fibrillation. This drug is useful for helping to maintain a regular, stable heart rate. Propafenone is known as an anti-arrhythmic drug. This drug works by blocking the activity of certain electrical signals in the heart that can cause an irregular heartbeat. Treating arrhythmias can reduce the risk of heart attack or stroke.
How do you use the drug Propafenone?
Read the patient information leaflet if applicable from the pharmacist before you start using Propafenone and each time you get a refill. If you have questions, ask your doctor or pharmacist.
Take this medication with or without food, usually every 12 hours or as directed by your doctor.
Swallow the capsule whole. Do not crush or chew the capsules because they can release all of the medicine at the same time, increasing the risk of side effects.
Dosage is based on medical condition and response to treatment.
Use the medicine regularly for maximum benefits. To help you remember, take it at the same time each day. Avoid eating citrus fruits or drinking orange juice while taking this medicine if your doctor or pharmacist has approved you. Jeruh fruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.
Tell the doctor if the condition does not get better or gets worse.
How to store Propafenone?
Store the medicine at room temperature away from light and moisture. Do not store in the bathroom and freeze medication. Medicines under different brands may have different storage methods. Check the product box for instructions on how to store it, or ask the pharmacist. Stay away from children and pets.
It is forbidden to flush the medicine in the toilet or throw it down the drain if not instructed to. Properly discard this product if it is past the deadline or is no longer needed. Consult a pharmacist or local waste disposal company for more in-depth details on how to safely dispose of the product.
Precautions & Warnings
What should be considered before using the drug Propafenone?
In a decision to use a drug, the risks of the drug must be weighed against its benefits. It is a decision you and your doctor will make. For this drug, the following should be considered:
Allergy
Tell your doctor if you have had any unusual or allergic reactions to this medicine or any other medicines. Also, tell your healthcare professional if you have any other types of allergies, such as food, coloring, preservatives, or animals. For over-the-counter products, read labels or packaging materials carefully.
Children
Adequate studies have not been carried out on the relationship of age to the effects of Propafenone in the pediatric population. Safety and efficacy have not been confirmed.
Elderly
The adequate studies conducted so far have not shown that specific disorders in the elderly will limit the benefits of Propafenone in the elderly.
Is the drug Propafenone safe for pregnant and lactating women?
There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This medicine is included in the pregnancy risk category C (A = No risk, B = No risk in some studies, C = Possible risk, D = There is positive evidence of risk, X = Contraindicated, N = Unknown)
Side effects
What are the possible side effects of Propafenone?
Get emergency medical help if you experience any of these signs of an allergic reaction: hives; difficulty breathing; swelling of the face, lips, tongue, or throat.
Contact your doctor immediately if you experience serious side effects such as:
- Shortness of breath, even when not exerting too much energy
- Swelling, weight gain very quickly
- Chest pain, very fast, irregular or pounding heartbeat
- Fever, chills, sore throat, flu symptoms, weakness
- Confusion, unnatural thoughts or habits
- Seizures
- Slow heart rate, weak pulse, fainting, slow breathing (breathing may stop)
Milder side effects may include:
- Dizziness, anxiety, loss of balance or coordination
- Unusual or unpleasant taste in the mouth
- Nausea, vomiting, constipation, loss of appetite
- Warm, red, or tingling feeling under the skin
- Headache
- Feel tired
- Ringing in ears
- Unusual dreams
- Blurry vision
Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.
Drug Interactions
What drugs can interfere with the drug Propafenone?
Using this medication with the following medicines is not recommended. Your doctor may decide not to treat you with this drug or change some of the drugs you take.
- Amifampridine
- Bepridil
- Cisapride
- Dronedarone
- Fluconazole
- Ketoconazole
- Levomethadyl
- Mesoridazine
- Nelfinavir
- Pimozide
- Piperaquine
- Posaconazole
- Ritonavir
- Saquinavir
- Sparfloxacin
- Terfenadine
- Thioridazine
- Tipranavir
- Propafenone
Using this medication with the medicines below is usually not recommended, but may be needed in some cases. If the two drugs are prescribed together, your doctor may change the dose or the length of time you take one or both drugs.
- Acecainide
- Ajmaline
- Alfuzosin
- Amiodarone
- Amisulpride
- Amitriptyline
- Amoxapine
- Anagrelide
- Apomorphine
- Aprindine
- Aripiprazole
- Arsenic Trioxide
- Artemether
- Asenapine
- Astemizole
- Azimilide
- Azithromycin
- Boceprevir
- Bretylium
- Bupropion
- Buserelin
- Carbamazepine
- Ceritinib
- Chloral Hydrate
- Chloroquine
- Chlorpromazine
- Ciprofloxacin
- Citalopram
- Clarithromycin
- Clomipramine
- Cobicistat
- Crizotinib
- Dabrafenib
- Darunavir
- Dasatinib
- Deferasirox
- Delamanid
- Delavirdine
- Desipramine
- Deslorelin
- Dibenzepin
- Digoxin
- Disopyramide
- Dofetilide
- Dolasetron
- Domperidone
- Droperidol
- Duloxetine
- Eltrombopag
- Enflurane
- Erythromycin
- Escitalopram
- Eslicarbazepine Acetate
- Etravirine
- Fingolimod
- Flecainide
- Fluoxetine
- Foscarnet
- Gatifloxacin
- Gemifloxacin
- Gonadorelin
- Goserelin
- Granisetron
- Halofantrine
- Haloperidol
- Halothane
- Histrelin
- Hydroquinidine
- Ibutilide
- Idelalisib
- Iloperidone
- Imipramine
- Isoflurane
- Isradipine
- Ivabradine
- Lapatinib
- Leuprolide
- Levofloxacin
- Lidocaine
- Lidoflazine
- Lopinavir
- Lorcainide
- Lumefantrine
- Mefloquine
- Methadone
- Metronidazole
- Mifepristone
- Mirabegron
- Mirtazapine
- Mitotane
- Moxifloxacin
- Nafarelin
- Nilotinib
- Norfloxacin
- Nortriptyline
- Octreotide
- Ondansetron
- Paliperidone
- Pazopanib
- Pentamidine
- Perflutren Lipid Microsphere
- Pirmenol
- Prajmaline
- Prilocaine
- Primidone
- Probucol
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Protriptyline
- Quetiapine
- Quinidine
- Quinine
- Ranolazine
- Risperidone
- Salmeterol
- Sematilide
- Sertindole
- Sertraline
- Sevoflurane
- Siltuximab
- Simeprevir
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
- Solifenacin
- Sorafenib
- Sotalol
- Spiramycin
- Sulfamethoxazole
- Sultopride
- Sunitinib
- Tedisamil
- Telaprevir
- Telithromycin
- Tetrabenazine
- Tizanidine
- Toremifene
- Trazodone
- Trifluoperazine
- Trimethoprim
- Trimipramine
- Triptorelin
- Vandetanib
- Vardenafil
- Vasopressin
- Vemurafenib
- Vilanterol
- Vinflunine
- Voriconazole
- Zolmitriptan
- Zotepine
Using this medication with any of the following medicines may increase your risk of side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor may change the dose or the length of time you take one or both drugs.
- Cyclosporine
- Paroxetine
- Rifampin
- Rifapentine
- Theophylline
- Tolterodine
- Warfarin
Can certain foods and drinks interfere with the work of the drug Propafenone?
Certain drugs cannot be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. The interactions below have been selected based on their significant potential and are not necessarily inclusive.
Using this medication with any of the following is usually not recommended, but may not be avoided in some cases. If used at the same time, your doctor may change the dose or length of time you use this medication, or give specific instructions about consumption of food, alcohol, or tobacco.
- Orange juice
- Tobacco
What health conditions can interfere with the performance of the drug Propafenone?
The presence of other medical disorders may affect the use of this drug. Make sure you tell your doctor if you have other medical problems, especially:
- Asthma
- Bronchitis
- Emphysema - propafenone can increase respiratory distress.
- AV inhibition (a type of heart rhythm disorder), without a pacemaker
- Bradycardia (slow heart rate)
- Respiratory disorders or lung disease (eg bronchospasm, severe obstructive pulmonary disease)
- Brugada syndrome (genetic heart rhythm disorder)
- Cardiogenic shock (shock from a heart attack)
- Heart failure
- Hypotension (low blood pressure)
- Mineral imbalance
- Sick sinus node syndrome (a type of heart rhythm disorder), without a pacemaker - Should not be used in patients with this condition.
- Blood or bone marrow disorders (eg agranulocytosis, granulocytopenia)
- Coronary artery disease
- Heart rhythm disturbances (eg QT prolongation)
- Myasthenia gravis (severe muscle weakness)
- Torsade de pointes
- Ventricular fibrillation or tachycardia - Use with caution. Maybe exacerbate this condition.
- Kidney disease or
- Liver disease - Use with caution. The effect may increase due to the slower disposal of the drug from the body.
- If you have a permanent pacemaker - Use with caution. Propafenone may interfere with the work of the pacemaker and require careful follow-up from a doctor.
Dose
The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.
What is the dose of the drug Propafenone for adults?
Usual adult dosage for atrial fibrillation:
Immediate release: 150 mg orally every 8 hours
Extended release: 225 mg every 12 hours.
Immediate release: May increase over 3-4 day intervals to 225 mg every 8 hours and, if necessary, 300 mg every 8 hours.
Extended release: May increase after 5 days of therapy to 325 mg every 12 hours. Doses increased to 425 mg every 12 hours are important for some patients.
Usual adult dose for atrial flutter
Immediate release: 150 mg orally every 8 hours
Extended release: 225 mg every 12 hours.
Immediate release: May increase over 3-4 day intervals to 225 mg every 8 hours and, if necessary, 300 mg every 8 hours.
Extended release: May increase after 5 days of therapy to 325 mg every 12 hours. Doses increased to 425 mg every 12 hours are important for some patients.
Usual adult dose for ventricular tachycardia
Immediate release: 150 mg orally every 8 hours
Extended release: 225 mg every 12 hours.
Immediate release: May increase over 3-4 day intervals to 225 mg every 8 hours and, if necessary, 300 mg every 8 hours.
Extended release: May increase after 5 days of therapy to 325 mg every 12 hours. Doses increased to 425 mg every 12 hours are important for some patients.
Usual adult dose for Wolff-Parkinson-White syndrome
Immediate release: 150 mg orally every 8 hours
Extended release: 225 mg every 12 hours.
Immediate release: May increase over 3-4 day intervals to 225 mg every 8 hours and, if necessary, 300 mg every 8 hours.
Extended release: May increase after 5 days of therapy to 325 mg every 12 hours. Doses increased to 425 mg every 12 hours are important for some patients.
What is the dosage of the drug Propafenone for children?
Safety and effectiveness have not been confirmed in pediatric patients (less than 18 years).
In what dosages and preparations is Propafenone available?
Tablets: 150 mg; 225 mg
What to do in an emergency or overdose?
In case of an emergency or overdose, contact the local emergency services provider (118/119) or immediately to the nearest hospital emergency department. Overdose symptoms may include:
- Tired
- Slow or irregular heartbeat
- Convulsions
What should I do if I forget to take medicine or forget to take medicine?
If you forget a dose of this medicine, take it as soon as possible. However, when it is near the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.
Hello Health Group does not provide medical consultation, diagnosis or treatment.
