Table of contents:
- What drug Imipenem?
- What is imipenem for?
- How do I use imipenem?
- How do I save imipenem?
- Imipenem dosage
- What is the dose of imipenem for adults?
- What is the dose of imipenem for children?
- In what dosage is imipenem available?
- Imipenem side effects
- What side effects can be experienced due to imipenem?
- Imipenem Drug Warnings and Cautions
- What should be known before using imipenem?
- Is imipenem safe for pregnant and lactating women?
- Imipenem Drug Interactions
- What medicines may interact with imipenem?
- Can food or alcohol interact with imipenem?
- What health conditions can interact with imipenem?
- Imipenem overdose
- What should I do in an emergency or overdose?
- What should I do if I miss a dose?
What drug Imipenem?
What is imipenem for?
Imipenem is a drug used for susceptible infections, prophylaxis for surgical infections, and mild to moderate susceptible infections.
How do I use imipenem?
This medication is given by injection into a muscle or vein, usually every 6-8 hours or as directed by your doctor. Dosage is based on medical condition and response to treatment.
If you are using this medication yourself at home, learn all preparation and instructions for use from a healthcare professional. Before using, check this product to see if there is any contamination or discoloration. If both occur, do not use liquids. Learn how to store and dispose of medical supplies safely.
Antibiotics work best when the amount of medicine in your body is at a constant level. Therefore, use this drug in an even space of time.
Use this medication until the time the full prescription treatment is over, even if symptoms disappear after a few days. Stopping this drug too quickly can cause the infection to return.
Tell your doctor if condition persists or worsens.
How do I save imipenem?
This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.
Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.
Imipenem dosage
The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.
What is the dose of imipenem for adults?
Intravenous
Prone to infection
Adults: Combined with cilastatin: (as anhydrous imipenem) 1-2 g daily divided doses every 6-8 hours, given by IV infusion. Doses of 250-500 mg infused for up to 20-30 minutes, and doses of 750 mg or 1 g for up to 40-60 minutes. Maximum: 4 g / day or 50 mg / kg.
Intravenous
Surgical prophylaxis infection
Adults: 1 g can be given during induction of anesthesia, followed by 1 g the next 3 hours, with an additional 500 mg dose 8-16 hours after induction if needed.
Intramuscular
Prone to mild to moderate infections
Adults: 500 or 750 mg every 12 hours.
Intramuscular
Gonorhea without complications
Adults: 500 mg as a single drug
What is the dose of imipenem for children?
Intravenous
Prone to infection
Children:> 40 kg: same as adult dose. Children> 3 months and <40 kg: 15-25 mg / kg every 6 hours by IV infusion. Doses up to 90 mg / kg can be given in older children with cystic fibrosis. Neonates and infants <3 months: 4 weeks - 3 months, 25 mg / kg every 6 hours; 1-4 weeks, 25 mg / kg every 8 hours; over 1 week, 25 mg / kg every 12 hours. Maximum:> 40 kg: 4 g / day or 50 mg / kg; <40 kg: 2 g / day.
In what dosage is imipenem available?
Powdered solution, Intravenous: 250 mg / 20 mL, 500 mg / 20 mL.
Imipenem side effects
What side effects can be experienced due to imipenem?
Side effects include:
- skin rash
- urticaria
- eosinophilia
- fever
- nausea
- gag
- diarrhea
- discoloration of teeth or tongue
- flavors that change
- changes to many forms of erythema
- exfoliative dermatitis
- pain and thrombophlebitis may occur at the point of injection
Not everyone experiences this side effect. There may be some side effects not listed above. If you are concerned about the side effects please consult your doctor or pharmacist.
Imipenem Drug Warnings and Cautions
What should be known before using imipenem?
Before using this medication, tell your doctor and pharmacist if you are allergic to imipenem, penicillin, cephalosporins, or any other medication. Tell your doctor and pharmacist what prescription and nonprescription drugs you are taking, especially antibiotics and vitamins.
Tell your doctor if you have or have had seizures, brain injury, kidney, liver, or gastrointestinal disease (especially colitis), or asthma.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using imipenem and cilastatin, call your doctor.
If you have diabetes and regularly check your urine for sugar, use the clinistix or testape. Do not use clinites tablets as they can cause false positive results.
Is imipenem safe for pregnant and lactating women?
There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).
The following references the pregnancy risk categories according to the FDA:
- A = No risk,
- B = not at risk in several studies,
- C = May be risky,
- D = There is positive evidence of risk,
- X = Contraindicated,
- N = Unknown
There are not sufficient studies in women to find out the risk to the baby when the mother takes this drug during breastfeeding. Consider the potential benefits and potential risks before taking this medication during breastfeeding.
Imipenem Drug Interactions
What medicines may interact with imipenem?
Interactions with other drugs can affect how the drug works and increase the risk of dangerous side effects. This article does not list all possible drug interactions. Record all medicinal products you use (including prescription, non-prescription and herbal medicines) and show them to your doctor and pharmacist. Do not start, stop, or change the dose of any medication without your doctor's permission.
For Imipenem, here are some things you need to pay attention to:
- the risk of seizures increases when you take this drug with ganciclovir
- ciclosporin can increase the neuro-ifosfamide toxin; ifosfamide can also raise serum ciclosporin levels
- serum levels can be increased with uricosuric agents. May reduce the efficacy of valproic acid. Monitor their use
Can food or alcohol interact with imipenem?
Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.
What health conditions can interact with imipenem?
The presence of other medical problems can affect the use of this drug. Make sure you tell your doctor if you have any other medical problems, specifically:
- hypersensitivity to other β-lactams due to possible cross-sensitivity
- CNS disorders such as epilepsy, kidney damage, liver damage
Imipenem overdose
What should I do in an emergency or overdose?
In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.
What should I do if I miss a dose?
If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
