Home Drug-Z Rosiglitazone: functions, dosage, side effects, how to use it
Rosiglitazone: functions, dosage, side effects, how to use it

Rosiglitazone: functions, dosage, side effects, how to use it

Table of contents:

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Rosiglitazone What Medicine?

What is rosiglitazone for?

Rosiglitazone is an anti-diabetic drug (known as glitazones) which is usually used with food and exercise programs to control high blood sugar in type 2 diabetes patients.

Rosiglitazone works to balance the body's response to insulin, so it can lower blood sugar levels. Controlling high sugar levels can prevent kidney damage, blindness, nervous system problems, organ loss, and sex organ function problems. Diabetes control may reduce the risk of heart attack or stroke.

How to use rosiglitazone?

Read the drug manual and the Patient Information Leaflet available at the pharmacy, if available, before you get this medication and each time you buy it again. If you have questions, ask your doctor or pharmacist.

Take this medication with or without food, usually 1 or 2 times a day, or according to your doctor's instructions. The dosage given is based on your medical condition, response to therapy, and if you are taking other anti-diabetic drugs.

Take this medicine regularly for optimal benefits. To help you remember, take this medication at the same time each day. Check your blood glucose level regularly.

This drug will show maximum results after 2-3 months of use.

Use all diabetes medications given by your doctor.

How is rosiglitazone stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Rosiglitazone dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for rosiglitazone for adults?

Initial dose: 4 mg orally once a day.

Adjusted dose: if the response has not been sufficient for 8-12 weeks, increase the dose to 8 mg once daily.

Maximum dose: 8 mg per day.

What is the dosage of rosiglitazone for children?

There is no provision for the dose of this drug for children. This medicine can be dangerous for children (under 18 years).

In what dosage is rosiglitazone available?

Tablets: 2 mg; 4 mg; 8 mg.

Rosiglitazone side effects

What side effects can be experienced due to rosiglitazone?

Seek medical help right away if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Stop using rosiglitazone and call your doctor if you experience serious side effects such as:

  • shortness of breath, despite light activity
  • swelling or rapid weight gain
  • chest pain or heaviness, radiating pain in the chest, shoulders, sweating, feeling unwell
  • nausea, stomach pain, low-grade fever, loss of appetite, dark urine, pale colored stools, jaundice (yellowing of the eyes and skin)
  • blurred vision
  • increased thirst or hunger, urinating more than usual
  • pale skin, easy bruising or bleeding, weakness

Less serious side effects:

  • flu symptoms such as congestion, sneezing, sore throat
  • headache
  • back pain

Not everyone experiences the above side effects. There may be some unspecified side effects. If you have concerns about certain side effects, consult your doctor or pharmacist.

Rosiglitazone Drug Warnings and Cautions

What should be known before using rosiglitazone?

Before using certain drugs, consider the risks and benefits first. This is a decision you and your doctor will have to make. For rosiglitazone, pay attention to the following:

Allergy

Tell your doctor if you have any unusual or allergic reactions to this or any other medicine. Also tell your doctor if you have any other types of allergies such as to food, coloring, preservatives, or animal allergies. For over-the-counter products, read the labels on the packaging carefully.

Children

Further studies on the relationship between age and the effects of rosiglitazone in children have not been found. The safety and efficiency of the drug has not been determined.

Elderly

There are no studies on the use of this drug in the elderly with age problems that can limit the use of rosiglitazone in the elderly.

Is rosiglitazone safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

  • A = Not at risk
  • B = No risk in several studies
  • C = May be risky
  • D = There is positive evidence of risk
  • X = Contraindicated
  • N = Unknown

Rosiglitazone Drug Interactions

What medicines may interact with rosiglitazone?

Although some drugs should not be taken together, in other cases some drugs can also be used together, although interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Using this medication with some of the medicines below is not usually recommended, but in some cases it may be necessary. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.

  • Abiraterone Acetate
  • Balofloxacin
  • Besifloxacin
  • Ceritinib
  • Ciprofloxacin
  • Dabrafenib
  • Enoxacin
  • Entacapone
  • Fleroxacin
  • Flumequine
  • Gatifloxacin
  • Gemifloxacin
  • Aspart Insulin, Recombinant
  • Degludec Insulin
  • Insulin Detemir
  • Glulisine Insulin
  • Human Inhaled Insulin
  • Human Isophane (NPH) Insulin
  • Human Regular Insulin
  • Lyspro Insulin, Recombinant
  • Levofloxacin
  • Lomefloxacin
  • Moxifloxacin
  • Nadifloxacin
  • Nitisinone
  • Norfloxacin
  • Ofloxacin
  • Pazufloxacin
  • Pefloxacin
  • Pixantrone
  • Prulifloxacin
  • Rufloxacin
  • Sparfloxacin
  • Tosufloxacin

Taking this drug with the drugs below may increase your risk of side effects. However, in some cases, a combination of these two drugs may be the best treatment. If these two drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.

  • Pariah
  • Fenofibrate
  • Fenugreek
  • Gemfibrozil
  • Glucomannan
  • Guar Gum
  • Psyllium
  • Rifampin
  • Trimethoprim

Can food or alcohol interact with rosiglitazone?

Certain drugs should not be used with meals or at certain foods because they can cause drug interactions. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with rosiglitazone?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

  • angina, severe and acute
  • diabetes ketoacidosis (ketones in the blood)
  • heart attack, acute
  • heart failure, severe or symptomatic
  • type 1 diabetes — should not be used with patients with these conditions
  • patients with kidney disease — this drug should not be combined with metformin in this patient's condition
  • diabetes macular edema (swelling at the back of the eye)
  • edema (difficulty urinating or swelling)
  • heart attack, history
  • heart disease, history
  • liver disease - use with caution, may worsen the condition
  • fever
  • infection
  • operation
  • trauma — use with caution as it can cause problems with blood sugar control
  • brittle bones (especially women) - use with caution as this can increase the risk of fracture

Rosiglitazone overdose

What should I do in an emergency or overdose?

In case of emergency or overdose, contact your local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Rosiglitazone: functions, dosage, side effects, how to use it

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