Cycloserine: functions, dosage, side effects, how to use

What Drug Cycloserine?

What is cycloserine for?

Cyloserine is an antibiotic drug. Cycloserine is an antibiotic that is often used to treat bacterial infections such as tuberculosis (TB). In some cases, this drug can also be used to treat urinary tract infections (UTIs).

This antibiotic treats only bacterial infections, so it will not work for viral infections (such as colds, flu). The unnecessary use of antibiotics or the abuse of any antibiotics can cause their effectiveness to decrease.

How is cycloserine used?

Take this medication with or without food, usually twice daily (every 12 hours) or as directed by your doctor.

Dosage is based on body weight, medical condition, cycloserine blood level, and response to treatment. Do not use more than 1000 mg per day.

Antibiotics work best when the amount of medicine in your body is at a constant level. Therefore, take this drug regularly. To help you remember, use it at the same time every day.

Continue to use this drug (and other TB drugs) until the prescribed amount is finished, even if symptoms have cleared up. Stopping treatment too early or skipping doses allows bacteria to continue to grow, which can result in a return of the infection and make the infection harder to treat (resistant to).

Your doctor may also direct you to take vitamin B6 (pyridoxine) to help prevent certain side effects of cycloserine. Follow the doctor's instructions carefully.

Tell your doctor if your condition does not improve or gets worse.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How is cycloserine stored?

Cycloserine is a drug that should be stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Cycloserine dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of cycloserine for adults?

To treat tuberculosis, the dose of cycloserine is:

• 500 mg to 1 gram orally per day, in 1 or 2 divided doses (10 to 15 mg / kg / day). Treatment should continue until permanent bacteriological changes have occurred and maximum clinical improvement has occurred, generally over a period of 18 to 24 months.

What is the dose of cycloserine for children?

To treat tuberculosis in children, the dose of cycloserine is:

• 10 to 15 mg / kg / day in 2 divided doses. The maximum dose is 1 g / day

In what dosage is cycloserine available?

The available cycloserine dosages are:

• 125 mg and 250 mg tablets
• 125 mg and 250 mg capsules

Cycloserine side effects

What side effects can be experienced due to cycloserine?

Call your doctor if you have any of the following serious side effects:

• Allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives)
• Seizures
• Numbness or tingling in the hands or feet
• Skin rash
• Confusion or unusual behavior
• Tremor (shaking)
• Headache
• Sleepy
• Dizzy
• Trouble speaking
• Irritability

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Cycloserine Drug Warnings and Cautions

What should be known before using cycloserine?

In deciding to use this drug, the risks of using the drug must be weighed against its benefits. The decision is up to you and your doctor. For this drug, the following should be considered:

• Allergy.Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. In addition, tell your doctor if you have any other types of allergies, such as allergies to foods, dyes, preservatives or animals. For non-prescription medicinal products, read the label or list of ingredients that make up the drug carefully.
• Children.Although there is no specific information comparing cycloserine use in children with those used in other age groups. However, it is hoped that this drug does not cause the different side effects or problems in children as it does in adults.
• Elderly.Many drugs have not been studied specifically in older people. Therefore, it may not be known whether this drug works in the same way as it does in young adults. Ask your doctor for more information.

Is cycloserine safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA) of the United States, or the equivalent of the Indonesian Food and Drug Administration Agency.

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = Maybe risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

Cycloserine Drug Interactions

What medicines may interact with cycloserine?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Although certain drugs should not be used at the same time, in other cases two different drugs can be used together even if interactions are possible. In this case, your doctor may want to change the dose or take other precautions that may be needed. Tell your health care professional if you are taking any other prescription or nonprescription drugs on the market.

Can food or alcohol interact with cycloserine?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with cycloserine?

The presence of other health problems in your body may affect the use of this drug. Some of the conditions that may interact with the drug cycloserine are:

• Alcohol abuse or a history of alcohol abuse
• Seizure disorders such as seizures or epilepsy
• Kidney illness
• Mental disorders such as mental depression, psychosis, or severe anxiety

Cycloserine overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.