Carboprost: functions, dosage, side effects, how to use

What medicine is Carboprost?

What is carboprost for?

Carboprost is a form of prostaglandin (a hormone substance that occurs naturally in the body). Prostaglandins help to control functions in the body such as blood pressure and muscle contraction.

Carboprost is a drug used to treat heavy bleeding after childbirth (postpartum). Carboprost drugs are also often used to induce abortion by causing uterine contractions. This medication is usually given between the 13th and 20th weeks of pregnancy, but may be given at other times for medical reasons.

Carboprost is a drug that is often used when other methods of abortion. This occurs when the woman has not completely emptied the uterus, or when complications of pregnancy will cause the baby to be born too early to survive. Carboprost can also be used for purposes not listed in the medication guide.

How do I use Carboprost?

Carboprost is a drug that is given as an injection into a muscle. You will receive this injection at a clinic or hospital. You may be given medicine to prevent nausea, vomiting, or diarrhea while you receive carboprost.

To make sure this medicine is working effectively, your cervix (opening of the uterus) will need to be checked after undergoing a treatment procedure. Don't miss any follow-up visits scheduled with your doctor.

In some cases, carboprost may not trigger a complete abortion and the procedure will have to be repeated.

How do I store Carboprost?

Carboprost is a medicine that can be stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Carboprost dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the carboprost dosage for adults?

• Initial dose: 250 mcg (1 mL) simultaneously by injection into the muscle with a tuberculin syringe.
• Subsequent doses of 250 mcg (1 mL) may be given at 1.5–3.5 hour intervals depending on uterine response.
• An optional test dose of 100 mcg (0.4 ml) can be given initially. The dose may be increased to 500 mcg (2 mL) if uterine contractility is judged to be inadequate after multiple doses of 250 mcg (1 mL).

The maximum total dose is 12 mg. Meanwhile, the duration of therapy is not more than 2 days continuously

Normal Adult Dose for Postpartum Bleeding:

• Initial dose: 250 mcg (1 mL) simultaneously by injection into muscle in additional doses may be given at 15 to 90 minute intervals, if necessary. Maximum total dose: 2 mg (8 doses).

What is the dosage of Carboprost for children?

Safety and effectiveness in pediatric patients (less than 18 years) have not been determined.

In what dosages is Carboprost available?

Carbprost drugs are available in injection form.

Carboprost side effects

What side effects can be experienced due to carboprost?

Get emergency medical help if you have any of the following signs of an allergic reaction: hives, difficulty breathing swelling of the face, lips, tongue, or throat.

Call your doctor right away if you have any of the serious side effects as below:

• severe pelvic pain, cramping, or vaginal bleeding
• high fever
• dizziness or shortness of breath
• severe nausea, vomiting, or diarrhea
• increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizures).

Carboprost is a drug that can cause common side effects including:

• low-grade fever that may come and go
• chills, numbness, or a tingling feeling
• mild nausea or diarrhea
• cough
• headache
• breast pain
• pain such as menstrual pain
• ears buzzing

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Carboprost Drug Warnings and Cautions

What should be known before using carboprost?

You should not use this medication if you are allergic to carboprost, or have certain conditions. Tell your doctor if you have:

• pelvic inflammatory disease
• lung disorders or breathing problems
• heart disease
• kidney disease or
• liver disease.

Before using carboprost, it's a good idea to tell your doctor if you are allergic to any medications, or if you have:

• high or low blood pressure
• diabetes
• epilepsy or other seizure disorder
• any scar tissue in your uterus
• history of asthma
• history of heart, kidney, or liver disease.

If you have this condition, you may not be able to use carboprost, or you may need a dose adjustment or special tests during treatment.

Is Carboprost safe for pregnant or breastfeeding women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C (according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Carboprost Drug Interactions

What medicines may interact with carboprost?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Before you use carboprost, tell your doctor if you have been treated with other drugs that can cause uterine contractions, such as:

• dinoprostone (Prostin E2)
• mifepristone (Mifeprex (RU-486)
• misoprostol (Cytotec)
• oxytocin (Pitocin).

Carboprost is a drug that can increase the effects of other medicines, and they do not have to be taken together.

Can food or alcohol interact with Carboprost?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with Carboprost?

Carboprost is a drug that can affect your health condition. Always tell your doctor if you have other health problems, including:

• adrenal gland disease - Carboprost can stimulate the body to produce more steroids
• anemia - in some patients, abortion by injecting Carboprost can result in blood loss which may require transfusion
• asthma (history)
• lung disease - Carboprost is a medicine that can cause narrowing of the blood vessels in the lungs or narrowing of the lung passages
• type 2 diabetes mellitus
• epilepsy (or history) - rarely, seizures occur with carboprost use
• uterine fibroid tumor
• uterine surgery - this medication can increase the risk of uterine rupture
• glaucoma - rarely, the pressure inside the eye has increased during carboprost use
• heart or vascular disease
• high blood pressure
• low blood pressure - Carboprost is a medication that can cause changes in heart function or changes in blood pressure
• jaundice
• Kidney illness
• liver disease - may make medications work longer or cause toxic effects

Carboprost overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.