Lidocaine + epinephrine: functions, dosage, side effects, how to use

Lidocaine + Epinephrine What Drugs?

What is lidocaine + epinephrine for?

Lidocaine Hydrochloride and Epinephrine Injection, USP, are indicated for the production of local or regional anesthetics by infiltration techniques such as percutaneous injection, with peripheral nerve block techniques such as brachial plexus, and intercostal and with central nervous techniques such as lumbar and caudal epidural block, when the procedure is accepted for these techniques are described in standard textbooks.

How should lidocaine + epinephrine be used?

Inject Epinephrine / lidocaine as directed by your doctor. Check the label on the medicine for precise dosing instructions.
If you miss a dose of Epinephrine / lidocaine, call your doctor right away.
Ask your doctor any questions you have about taking Epinephrine / lidocaine.

How is lidocaine + epinephrine stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Lidocaine + Epinephrine dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

Follow your doctor's advice or the dosing instructions provided on the packaging.

Lidocaine + Epinephrine side effects

What side effects can I experience with lidocaine + epinephrine?

The side effects are:
⇒ Severe CNS and CVS side effects are directly related to lidocaine levels
⇒ side effects are more likely after systemic administration than infiltration; dizzy; muscle twitching; local anesthesia from the mouth / throat so that the swallowing process is disturbed and increases the risk of aspiration (eating or drinking for 3-4 hours after anesthesia)
⇒ transient effects on the neonatal hearing system; erythema
⇒pigmentation; pain; headache; palpitations; local necrosis; pulmonary edema; hyperglycemia; bradycardia; reduced cardiac output; anxiety
Epidurals can cause hypotension, bradycardia, nausea and vomiting
⇒ intraoral can cause stress reactions such as diaphoresis, palpitations, hyperventilation, pallor and fainting
⇒ topical: papules, burns, rashes, skin irritation, burning sensation and blanching.

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Drug Cautions and Warnings Lidocaine + Epinephrine

What should be known before using lidocaine + epinephrine?

Before taking this medication, tell your doctor:
⇒ if you are pregnant, planning to become pregnant, or are breastfeeding
⇒ if you are taking prescription or non-prescription drugs, herbal preparations, or dietary supplements
⇒ if you have an allergy to drugs, food or other substances
⇒ if you have a severe allergic reaction (for example, severe rash, hives, difficulty breathing, dizziness) to any anesthetic (for example, benzocaine)
⇒ if you have heart problems, irregular heartbeat, liver problems, kidney problems, blood vessel problems, high blood pressure, poor circulation, or very poor health

Is lidocaine + epinephrine safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is pregnancy risk category B according to the Food and Drug Administration (FDA).

The following FDA reference pregnancy risk categories:
• A = No risk,
B = No risk in some studies,
• C = There may be some risks,
• D = positive evidence of risk,
X = Contraindicated,
• N = unknown.

Lidocaine + Epinephrine Drug Interactions

What medicines may interact with lidocaine + epinephrine?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Phenothiazines (eg chlorpromazine) because of the risk of low blood pressure and heart palpitations can occur
Beta-blockers (eg propranolol), cimetidine, catechol-O-methyltransferase (COMT) inhibitors (eg entacapone), mexiletine, monoamine oxidase inhibitors (MAOIs) (eg phenelzine), or tricyclic antidepressants (eg imipramine) can increase the risk of effects. side of the epinephrine / lidocaine patch's iontophoretic
Antiarrhythmics (eg amiodarone, tocainide), bromocriptine, or other local anesthetics (eg benzocaine) due to the risk of side effects from epinephrine / lidocaine iontophoretic patches
Furazolidone or guanethidine as they may increase the effectiveness of the epinephrine / lidocaine patch.

Can food or alcohol interact with lidocaine + epinephrine?

Certain drugs should not be used with meals or around meals at certain foods or foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with lidocaine + epinephrine?

The presence of other medical problems may affect the use of this drug. Make sure you tell your doctor if you have any other medical problems, especially:
⇒ epilepsy
Cardiac conduction disorders
⇒ CHF
⇒ DM
Angle closure glaucoma
Impaired liver function.
⇒ cerebrovascular insufficiency
⇒ hyperthyroidism