Granon: functions, dosage, side effects, how to use it

Use

What is granon used for?

Granon is a brand of medicine that is available in injection liquid. This drug contains the main ingredient granisetron.

Granisetron is a drug that belongs to the 5-HT3 antagonist class, which is commonly used to reduce symptoms of nausea and vomiting.

Generally, granon drugs are given to cancer patients who are undergoing chemotherapy or radiation to prevent symptoms of nausea and vomiting.

Granon medicine works by blocking serotonin, a natural substance present in the body that can cause nausea and vomiting.

This drug is included in prescription drugs, so you cannot buy it over the counter at a pharmacy.

How do you use granon?

The following are some of the things you should pay attention to when using granon. Among them:

• This medication will be administered by a doctor or medical professional at the hospital.
• Usually, this drug is injected 30 minutes before chemotherapy. It can also be given before, during, or after surgery.
• This drug is given for 30 seconds or mixed into the intravenous fluid and given for 5 minutes.
• If your doctor recommends that you use this medicine at home, first understand how to use the product properly
• Don't forget to check the medicinal fluid; whether experiencing a change in color or appearing small particles in it.
• Do not mix other medicinal fluids when injecting this drug.
• The dose of this drug is determined based on your health condition or your reaction to administration of this medicine.
• If you are undergoing chemotherapy, a second dose of this drug is sometimes given 12 hours after the first dose.

How to store granon?

To store this drug, the following things can be used as a reference, such as:

• Store this medication at room temperature.
• Keep away from damp places.
• Don't keep it in the bathroom.
• Don't also store it frozen in the freezer.
• Keep away from direct sunlight or light.
• Keep this medication out of reach of children to pets.

If you are not using this drug, or the drug is not suitable for use, or the drug has expired, then you should immediately throw away the granon. However, follow the rules for disposing of medicinal waste according to the proper procedure.

Make sure that you do not mix medicinal waste with household waste. Do not also throw this medication in the toilet or other drains. If this is done, the medicinal waste will pollute the environment.

If you are not sure about the proper procedure for disposal of drugs, you should ask a medical professional such as a pharmacist or to the officer about the proper and safe procedure for disposing of the drug.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for granon for adults?

Adult dosage for nausea and vomiting after chemotherapy

• Preventive dose (IV):
  • 1-3 milligrams (mg) given by injection for 30 seconds
  • If dissolved into intravenous fluids, 20-50 milliliters (mL) are infused for 5 minutes before starting chemotherapy
• Maintenance dosage:
  • 1-3 mg given by injection for 30 seconds
  • If dissolved in intravenous fluids, 20-50 milliliters (mL) are infused for 5 minutes before starting chemotherapy.
  • If needed, an additional dose can be given at least 10 minutes after the previous dose.
  • Maximum dose: 9 mg / 24 hours.
• Preventive and maintenance (IM) dosage:
  • 3 mg injected through a muscle 15 minutes before starting chemotherapy.
  • If needed, additional doses can be given twice over a 24 hour period.

Adult dose for nausea and vomiting after radiotherapy

• Preventive dose (IV):
  • 1-3 mg given by injection for 30 seconds
  • If dissolved into intravenous fluids, 20-50 milliliters (mL) are infused for 5 minutes before starting radiotherapy

Adult dosage for postoperative nausea and vomiting

• Preventive dose (IV):
  • 1 mg given by injection for 30 seconds before induction of anesthesia.
• Maintenance dose (IV):
  • 1 mg given by injection slowly for 30 seconds
  • Maximum dose: 3 mg daily before induction of anesthesia before surgery
  • Maximum dose: 2 times the dose.

What is the dosage for granon for children?

Children's dosage for nausea and vomiting after chemotherapy

• A dose of 10-40 micrograms (mcg) / kg dissolved in 10-30 mL of intravenous fluid and given for 5 minutes before starting chemotherapy.

In what dosages is granon available?

Granon is available in doses of 1 mg / mL and 3 mg / mL

Side effects

What are the possible side effects of using granon?

As with using other medicines, the use of granon can also cause side effects of use. Side effects that occur are usually mild to severe health conditions.

Mild side effects that may arise are:

• Headache
• Constipation
• Sleep disturbances, such as insomnia or insomnia

However, if the mild side effects you are experiencing don't get better or get worse, contact your doctor immediately. However, there are also serious side effects that may occur, such as:

• Skin rash
• Skin feels itchy
• Hard to breathe
• Gasping for breath
• Swelling of the eyes, face, tongue and throat
• Chest tightness
• The area of ​​the skin that was injected turns red, bruised, or feels sore
• The stomach hurts and swells
• Changes in heart rate
• Tremors, loss of coordination, body stiffness
• Fever
• Excessive sweating
• Nausea, vomiting and diarrhea
• Seizures
• Hallucinations, changes in mental state, to coma

Not all side effects are listed above. In fact, you probably won't experience any side effects at all. However, if you experience other side effects after using granon, tell your doctor.

Warnings & Precautions

What to know before using granon?

Before using granon, there are a few things you should know, such as:

• Do not use this medication if you have an allergy to granon or the main active ingredient in it, namely granisetron.
• Tell your doctor if you:
  • have other allergies to drugs, food, dyes, preservatives, and even allergies to animals.
  • There is a history of heart disease, heart rhythm disorders, long QT syndrome, electrolyte imbalance.
  • recently had stomach or intestinal surgery.
  • are pregnant, planning to become pregnant, or are breastfeeding.
• Do not give this medicine to anyone under 18 years of age unless a doctor instructs you to do so.
• This medicine may make you feel dizzy. Avoid doing activities that require concentration.
• The elderly may be more susceptible and sensitive to the side effects of this drug.

Is granon safe to use for pregnant and lactating women?

It is not certain whether this drug can have a negative impact on the mother and the fetus.

However, if you are going to use this drug, consult your doctor first about the risks and benefits of using the drug. Only use medication if you absolutely need it.

In addition, it is still not known whether granon can pass through breast milk and is accidentally consumed by a nursing infant.

If you are using this medication while breastfeeding, check with your doctor first. Only use this medication if the benefits outweigh the risks.

Interaction

What medicines can interact with granon?

Drug interactions can occur if you use more than one drug at the same time. The interactions that occur can cause an increased risk of side effects or a change in how the drug works.

However, it is possible that drug interactions can increase drug action. Therefore, record all types of drugs you use, from prescription drugs, non-prescription drugs, herbal medicines, dietary supplements, to multivitamins. Then, give the note to the doctor so he can help you determine the dosage of the medication.

Do not start, stop, or change the dose of medication without your doctor's knowledge. Granon can interact with 293 types of drugs. However, the following are the types of drugs that interact most frequently, including:

• Demerol (meperidine)
• Dilaudid (hydromorphone)
• Emend (aprepitant)
• Fentanyl Transdermal System (fentanyl)
• Lexapro (escitalopram)
• MiraLax (polyethylene glycol 3350)
• Vitamin B12 (cyanocobalamin)
• Vitamin C (ascorbic acid)
• Vitamin D3 (cholecalciferol)
• Zofran (ondansetron)

What foods and alcohol can interact with granon?

Certain medications should not be consumed at mealtimes or when eating certain types of food because interactions may occur. Consuming alcohol or tobacco-derived products with certain drugs can also cause interactions.

When using granon, you should avoid using alcohol because it can increase one of the risks of drug side effects, namely headaches. Discuss with your health care professional the use of drugs with food, alcohol, or products derived from tobacco.

What health conditions can interact with granon?

Apart from interactions between drugs and interactions between drugs and food and alcohol, these drugs can also interact with various health conditions in your body.

The interactions that occur can affect how the drug works, increase the side effects of the drug, and worsen your health condition. It's best to tell your doctor about any health conditions you have or currently have so that the doctor can determine whether this drug is safe to use.

The following are diseases that you should tell your doctor about if you are going to use granon:

• Allergy to 5-HT3 antagonists
• Electrolyte imbalance
• Heart disease
• Heart rhythm disturbances

Overdose

What should I do in an emergency or overdose?

When using this drug, the chances of you having an overdose are very small. The reason is, this drug is given by professional medical experts. However, if you have an emergency case or overdose, contact your local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you miss a dose of medication, tell your doctor at least an hour before undergoing chemotherapy or radiation. Do not increase the dose to make up for a missed dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.