Table of contents:
- What Drug Bucillamine?
- What is bucillamine for?
- How do you use bucillamine?
- How is bucillamine stored?
- Bucillamine dosage
- What is the dosage of bucillamine for adults?
- What is the dosage of bucillamine for children?
- Bucillamine side effects
- What side effects can be experienced due to bucillamine?
- Bucillamine Drug Warnings and Cautions
- What should be known before using bucillamine?
- Is bucillamine safe for pregnant and lactating women?
- Bucillamine Drug Interactions
- What medicines may interact with bucillamine?
- Can food or alcohol interact with bucillamine?
- What health conditions may interact with bucillamine?
- Bucillamine overdose
- What should I do in an emergency or overdose?
- What should I do if I miss a dose?
What Drug Bucillamine?
What is bucillamine for?
Bucillamine is a drug used to treat rheumatoid arthritis, Wilson's disease, and certain disorders that cause kidney stones (cystinuria). Not only that, bucillamine is a type of disease-modifying antirheumatic drug (DMARD) which functions to relieve pain / swelling in joints.
For the treatment of Wilson's disease, penicillamine binds to copper and helps to remove it from the body. Decreased levels of copper help to improve liver function and psychiatric / mood / nervous problems (such as confusion, difficulty speaking / walking) caused by the disease. Meanwhile, for the treatment of cystinuria, the function of bucillamine is to help reduce the amount of certain substances (cystine) in the urine that can cause kidney stones.
OTHER USES: This section lists uses for this drug that are not listed on approved labels, but may be prescribed by your healthcare professional. Use this medication for the conditions listed below only if it has been prescribed by your doctor and health care professional.
Another function of bucillamine is to treat poisoning.
How do you use bucillamine?
Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.
Take this medication on an empty stomach (1 hour before or 2 hours after eating) as directed by your doctor. Take this medication at least 1 hour apart from other medicines (especially acid reflux drugs), milk, or food. The dosage is based on the medical condition and response to treatment.
Take this medicine regularly for optimal results. To help you remember, drink it at the same times each day.
Your doctor will also advise you to take vitamin B6 (pyridoxine) and iron. Follow your doctor's instructions carefully. If you need to consume iron or other products that contain minerals (such as zinc), take it at least 2 hours before or after taking Bucillamine. Consult your doctor before using other products that contain minerals as they can block the absorption of Bucillamine. For the treatment of rheumatoid arthritis, it can take about 2 to 3 months before you notice any improvement in your condition.
For the treatment of Wilson's disease, follow the nutritional intake recommendations given by your doctor for optimal benefit from this medication. Your condition may not improve for 1 to 3 months and may get worse when you start this treatment. Tell your doctor right away if your condition gets worse after a month of treatment.
For cystinuria treatment, follow the nutritional recommendations given by your doctor for optimal benefit from this medication. Drink enough water unless your doctor advises otherwise. Tell your doctor if your condition does not improve or gets worse.
How is bucillamine stored?
This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.
Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.
Bucillamine dosage
The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.
What is the dosage of bucillamine for adults?
For adults who have rheumatoid arthritis, the dose of bucillamine is 100 mg / day
What is the dosage of bucillamine for children?
There is no provision for the dosage of this drug for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use. Consult your doctor or pharmacist for more information.
Bucillamine side effects
What side effects can be experienced due to bucillamine?
Common side effects that may arise when using bucillamine are stomach pain, nausea / vomiting, loss of appetite, diarrhea, and decreased sense of taste.
Meanwhile, there could be serious side effects, so you should call for medical help or contact a doctor. The serious side effects of bucillamine include the following:
- Allergic reactions (shortness of breath, choking throat, difficulty breathing, swelling of your lips, face, or throat or hives)
- Fever or chills
- Sore throat
- Unusual bleeding or sores
- Blood in urine
- Unexplained shortness of breath, coughing, or sneezing
- Stomach ache
- Yellowing of the skin or eyes (jaundice / jaundice
- Muscle weakness
- Double vision
Less serious side effects are less likely to occur. Continue to use Bucillamine and tell your doctor if you experience:
- Hives or rash
- Nausea, vomiting, diarrhea or decreased appetite
- Ring in ears
- Decreased sense of taste
- Mouth pain
- wounds heal slowly, or
- increased wrinkles on the skin
Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.
Bucillamine Drug Warnings and Cautions
What should be known before using bucillamine?
What you should do before using bucillamine is tell your doctor or pharmacist if you are allergic to this drug, or penicillin, or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially previous severe reactions to Bucillamine (eg, aplastic anemia, agranulocytosis), kidney disease, blood or bone marrow disorders (such as thrombocytopenia).
Before performing surgery, tell your doctor or dentist all the products you use (including prescription / nonprescription drugs, and herbal products).
Is bucillamine safe for pregnant and lactating women?
There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category D according to the US Food and Drug Administration (FDA).
The following references the pregnancy risk categories according to the FDA:
- A = No risk,
- B = not at risk in several studies,
- C = May be risky,
- D = There is positive evidence of risk,
- X = Contraindicated,
- N = Unknown
There are not adequate studies in women determining the risk to the baby when using this medicine during breastfeeding. Consider the benefits against the risks before using this medication during breastfeeding.
Bucillamine Drug Interactions
What medicines may interact with bucillamine?
Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. When you are using this medication, it is important for your doctor to know if you are taking any of the drugs in the following list.
Taking this drug with any of the following medicines is not recommended. Your doctor may not prescribe this medicine to you or will replace some of the drugs you are already taking.
- Aurothioglucose
Using this medication with some of the medicines below is not usually recommended, but in some cases it may be necessary. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.
- Auranofin
- Gold Sodium Thiomalate
Taking this medication with the drugs below may increase your risk of side effects, but in some cases, a combination of these two drugs may be the best treatment. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.
- Iron
Can food or alcohol interact with bucillamine?
Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.
What health conditions may interact with bucillamine?
Any other health conditions you have can affect the use of this drug. Health conditions that must be notified to the doctor when you are going to use bucillamine are:
- have a history of blood diseases caused by Bucillamine treatment
- have a history of kidney disease (only in patients with rheumatoid arthritis) —the risk of developing side effects may increase.
Bucillamine overdose
What should I do in an emergency or overdose?
In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.
What should I do if I miss a dose?
If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.