Tresiba: functions, dosage, side effects, how to use it

Uses

What is Tresiba?

Tresiba is insulinlong-acting artificial (recombinant DNA) which helps the body's cells work in capturing insulin. The main active ingredient in it is insulin degludec. This insulin starts working a few hours after eating with a working period of up to 24 hours. Tresiba is used to help control blood sugar in patients who have been diagnosed with diabetes mellitus for one year or more, both type 1 diabetes and type 2 diabetes.

The use of this drug is not recommended for patients with diabetic ketoacidosis and pediatric diabetic patients requiring less than five Tresiba units.

Rules of use Tresiba

This drug is insulin that is injected into the subcutaneous tissue, which is the fat layer under the skin. The Tresiba prescribed to you has adapted to your need for insulin, so do not change the dose without consulting your doctor. To prevent lipodystrophy, change your injection point. You can still do the injection in the same area.

Giving injection can not only be done in the abdominal area. Injection can also be done in the thigh or upper arm area. Do not inject it directly into a vein and muscle as this can cause hypoglycemia.

Use this built-in insulin injection tool and don't forget to always replace the needle with a new one before injection. Do not share syringes with other people even if you have changed needles. Sharing syringes increases the risk of transmitting infections and other diseases.

What are the rules for saving Treasury?

Store this drug in a container that is protected from heat and direct sunlight. Don't freeze it inside freezer or near the cooling element in the refrigerator. Store in a temperature of 2-8 degrees Celsius. Throw away the frozen Tresiba, do not use it even though it has been re-adjusted to room temperature.

Save the unopened Tresiba

Unopened receipts can be stored up to their expiration date. Or if you keep it at room temperature, you can use it for up to eight weeks or the next 56 days.

Save the already opened Tresiba

Store the injection pen at room temperature. Do not store in the refrigerator and with the needle attached. Use it for a period of eight weeks.

Do not use Tresiba if the liquid looks cloudy or changes color. Contact your pharmacist for a new one.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the recommended dose of Tresiba?

The dosage given to people with diabetes depends on the patient's needs and how their body responds to it. In general, Tresiba injection is given once a day at any time for adult diabetic patients. Meanwhile, the administration of Tresiba for pediatric diabetic patients is carried out once a day at the same time.

Adults with type 1 diabetes

For those who have never had an insulin injection before, the initial dose given is one-third or half of the total insulin requirement once a day. In general, the total recommended daily dose of insulin is 0.2-0.4 units per kilogram of body weight. As for those on insulin therapy, equate the initial dose of Tresiba with another subcutaneous insulin injection once a day. The new dose can be increased after 3 to 4 days of routine injection done in consultation with a doctor.

Adults with type 2 diabetes

The initial dose of Tresiba for patients who have never received insulin therapy is 10 units in one injection a day. If you are on insulin therapy, start with the same amount as insulin long acting that is being used.

Children one year of age or older with diabetes

Use Tresiba with a starting dose of 80 percent of insulin requirements long acting to minimize the possibility of hypoglycemia.

Side effects

What side effects might occur due to using Tresiba?

Some of the side effects that may occur due to using Tresiba are:

• Hypoglycemia
• Allergic reactions
• Rash, pain, irritation, or redness and swelling at the injection site
• Itchy
• Headache
• Sinusitis
• Upper respiratory tract infection
• Upper abdominal pain
• Diarrhea
• Runny nose
• Weight gain

Lipodystrophy is also one of the side effects that may arise due to injection of this drug. Lipodystrophy occurs due to continuous injection at the same point, causing the appearance of fat lumps or grooves that can prevent insulin from working. This can be prevented by changing the injection point.

Not all possible side effects have been listed above. Other side effects that have not been mentioned above are possible. Talk to your doctor about the possible side effects that you are worried about will occur. Immediately contact your doctor if you find anything strange after injection of this drug.

Drug Interactions

What drugs may interact with Tresiba?

Several drugs cannot be used simultaneously because it will cause drug interactions. Drug interactions can increase the risk of side effects or prevent one drug from working optimally. Even so, the use of both drugs at the same time may sometimes be necessary. When your doctor decides to give two drugs that may interact at the same time, your doctor may make a dose adjustment.

Here are some lists of drugs that interact with the use of Tresiba:

• Antidepressants
• Antipsychotics
• Lithium
• Sympathomimetics
• Disopramid
• Diuretic
• Corticosteroids
• Somatropin
• Hypoglycemic
• Salicylates
• NSAID class drugs
• Sulfonamide
• Tetracycline
• Antimalarial
• Mebendazole
• Pentamidine
• Thyroid hormone
• Danazol
• Anabolic steroids
• Cyclophosphamide

Overdose

What should I do in an emergency or overdose?

Call 119 for emergency medical assistance. You can also go to the nearest hospital emergency room immediately if you find signs of an overdose. One sign of an overdose is hypoglycemia. The doctor may also prescribe glucagon along with Tresiba as a precaution for hypoglycemia. Make sure the people closest to you are aware of the use of this glucagon injection.

What should I do if I miss the injection?

Do the injection as soon as you remember. Make sure that the injection schedule has a gap of at least eight hours from the next schedule. Do not double the dose to make up for a missed injection.