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Streptomycin: functions, dosage, side effects, how to use

Streptomycin: functions, dosage, side effects, how to use

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What drug streptomycin?

What is Streptomycin for?

Streptomycin is a drug commonly used to treat tuberculosis (TB) and certain bacterial infections.

Streptomycin is an aminoglycoside. Works by killing sensitive bacteria that stop the production of essential proteins needed by bacteria to survive.

How to use Streptomycin?

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

Use streptomycin as directed by your doctor. Check the label on the medicine to confirm the dosage instructions.

  • Drinking more fluids while using streptomycin is recommended. Ask your doctor for instructions.
  • Streptomycin is usually given as an injection at your doctor's office, hospital, or clinic. If you are using streptomycin at home, carefully follow the procedure as instructed by your healthcare professional.
  • In adults, the recommended area for injection is the upper right side near the buttocks or the middle part of the thigh. In children, the recommended area for injection is the middle of the thigh.
  • The parts of the body being injected must vary
  • If streptomycin contains particles or changes color, or if the vial breaks or breaks, do not use it.
  • Keep this product, including syringes, out of reach of children and pets. Do not reuse needles or other materials. Discard immediately after use. Ask your doctor or pharmacist to explain local regulations for the correct disposal of this product.
  • To completely cure your infection, continue using streptomycin for its full treatment even if you feel well within a few days
  • If you forget a streptomycin dose, call your doctor right away

Ask a healthcare professional if you have questions about how to use streptomycin.

How is Streptomycin stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Streptomycin dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the Streptomycin dosage for adults?

Tuberculosis

IM 15 mg / kg / day (maximum, 1 g) or 25 to 30 mg / kg 2 or 3 times a week (maximum, 1.5 g)

Use with other Agents

IM 1 to 2 g divided doses every 6 to 12 hours for moderate to severe infections (maximum, 2 g / day)

What is the Streptomycin dosage for children?

Tuberculosis

IM 20 to 40 mg / kg / day (maximum, 1 g) or 25 to 30 mg / kg 2 or 3 times a week (maximum, 1.5 g).

Use with other Agents

IM 20 to 40 mg / kg / day divided doses every 6 to 12 hours, avoiding excessive doses.

In what dosage is Streptomycin available?

Streptomycin is available in the following dosages.

Injection 1 g (1 ea)

Streptomycin side effects

What side effects can be experienced due to Streptomycin?

If the following side effects occur during streptomycin use, check with your doctor or nurse immediately:

General symptoms

  • Dark stool
  • Feeling burning, itching, numbness, prickling, tingling sensations
  • Chest pain
  • Shivering
  • Clumsy
  • Cough
  • Dizziness or lightheadedness
  • Feel your surroundings keep moving
  • Fever
  • Itching, swelling of the face, eyelids, lips, tongue, throat, hands, feet, soles of the feet, or genital organs
  • Nausea
  • Pain or difficulty urinating
  • Feel spinning
  • Shortness of breath
  • Sore throat
  • Stomach sores, or there are white spots on the lips or mouth
  • Swollen glands
  • Not balanced
  • Unusual bleeding or bruising
  • Unusual feeling of fatigue or weakness
  • Throws up

Rare side effects

  • Pain in the back, legs, or stomach
  • Bleeding gums
  • Bloody urine / urine
  • Blurred vision
  • Changes in vision
  • Dark urine
  • Didn't hear
  • Difficulty breathing
  • Difficulty swallowing
  • Dry mouth
  • Fast heart rate
  • The whole body is swollen
  • Headache
  • Itchy rash
  • Vision deteriorates
  • Loss of appetite
  • Muscle weakness
  • Bloody nose
  • Back pain
  • Red spots on the skin
  • Swelling of the eyelids or around the eyes, face, lips, tongue
  • Skin rash
  • Thirsty
  • Chest tightness
  • Breath sounds
  • Yellowing of the eyes or skin

Rare conditions:

  • Changes in the frequency or amount of urine
  • Sleepy
  • Increased thirst
  • Swelling on the soles of the feet or lower legs
  • limp

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Streptomycin Drug Warnings and Cautions

What should be known before using Streptomycin?

Tell your doctor or pharmacist if you have any medical conditions, especially if the following conditions happen to you:

  • if you are pregnant, planning to become pregnant, or are breastfeeding
  • if you are using prescription or nonprescription drugs, herbal products, or nutritional supplements
  • if you have an allergy to drugs, food, or other substances.

Is Streptomycin safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category D according to the US Food and Drug Administration (FDA). The following references the pregnancy risk categories according to the FDA:

A = No risk,

B = not at risk in several studies,

C = May be risky,

D = There is positive evidence of risk,

X = Contraindicated,

N = Unknown

Streptomycin Drug Interactions

What medicines may interact with Streptomycin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Although several drugs should not be used simultaneously, in other cases two different drugs may be used simultaneously even if interactions are possible. In this case, your doctor may change the dose, or other precautions may be needed. Tell your doctor if you are taking any other prescription or over-the-counter drugs.

Tell your doctor if you are using any of the following drugs:

  • Fludarabine, indomethacin, or polypeptide antibiotics (for example, polymyxin B) because streptomycin side effects can increase
  • Cyclosporine, methoxyflurane, nonsteroidal anti-inflammatory drugs (NSAIDs) (for example, ibuprofen), nitrosoureas (for example, streptozocin), parental cephalosporins (for example, cephalexin), or parenteral vancomycin because toxicity to the kidneys can occur.
  • Loop diuretics (for example, furosemide) due to severe damage to the eighth cranial nerve, causing permanent hearing loss.
  • Nondepolarizing muscle relaxants (eg pancuronium), antibiotic polypeptides (eg polymyxin B), or succinylcholine because the side effects of these drugs can increase.

Can food or alcohol interact with Streptomycin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with Streptomycin?

The presence of other health problems in your body may affect the use of this medicine. Tell your doctor if you have other health problems, especially:

  • Diarrhea, damage to the eighth cranial nerve, infection of the stomach or intestines, or kidney failure
  • Dehydration (diarrhea, nausea or vomiting causes electrolyte imbalance)
  • Muscle weakness or Parkinson's disease.

Streptomycin overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Streptomycin: functions, dosage, side effects, how to use

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