Lisinopril + hydrochlorothiazide: functions, dosage, side effects, how to use

Lisinopril + Hydrochlorothiazide What Drug?

What is lisinopril + hydrochlorothiazide for?

This drug is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two drugs: lisinopril and hydrochlorothiazide. Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of excess salt and water. This product is used when one drug can't control your blood pressure. Your doctor may direct you to take an individual medication first, and then switch to this combination product. Do not continue to take individual drugs (lisinopril and / or hydrochlorothiazide) after you have started this medication.

OTHER USES: This section lists uses for this drug that are not listed on approved labels, but may be prescribed by your healthcare professional. Use this medication for the conditions listed below only if it has been prescribed by your doctor and health care professional. This drug can only be used to treat heart failure.

How to use lisinopril + hydrochlorothiazide?

Take this medication by mouth as directed by your doctor, usually once daily in the morning with or without food. If this medicine causes you to urinate more frequently, it is best to take it at least 4 hours before bed to prevent urinating while you are asleep.

If you are also taking certain medications to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take lisinopril / hydrochlorothiazide at least 4 hours before or at least 4 to 6 hours after taking these medications. Dosage depends on your medical condition and your response to treatment. Take this medicine regularly to get optimal benefits. To help you remember, take this medication at the same time each day. Do not stop using this drug even though you feel better.

Tell your doctor if your condition does not improve or gets worse (for example, your blood pressure has risen).

How to store lisinopril + hydrochlorothiazide?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets. Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Lisinopril + Hydrochlorothiazide dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of lisinopril + hydrochlorothiazide for adults?

Adult dosage for congestive heart failure

Initial dose: 1 tablet (hydrochlorothiazide-lisinopril 12.5 mg / 10 mg) once a day. Determine the dosage according to individual titrations.
Follow-up dose: Can be increased to a maximum of 2 tablets of (hydrochlorothiazide-lisinopril 25 mg / 20 mg) twice a day.

What is the dosage of lisinopril + hydrochlorothiazide for children?

The dosage for children is still unknown. Ask your doctor for more information.

In what dosage is lisinopril + hydrochlorothiazide available?

Tablets, Oral: 10 mg lisinopril and 12.5 mg hydrochlorothiazide, 20 mg lisinopril and 12.5 mg hydrochlorothiazide, 20 mg lisinopril and 25 mg hydrochlorothiazide.

Lisinopril + Hydrochlorothiazide side effects

What side effects can I experience due to lisinopril + hydrochlorothiazide?

Seek immediate medical help if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Call your doctor if you experience any of the following serious side effects:

⇒ felt like passing out
⇒ eye pain, vision problems
⇒ high potassium (slow heart rate, weak pulse, muscle weakness, tingling feeling)
⇒ low potassium (confusion, unstable heart rate, extreme thirst, increased urination, discomfort in the legs, muscle weakness or weakness)
⇒ dry mouth, thirst, nausea, vomiting
⇒ feeling weak, sleepy, or restless
⇒ skin red, blistering, rash
⇒ psoriasis (removes silvery peeling skin)
⇒ jaundice (yellowing of the skin or eyes)
⇒ urinating less than usual or not at all
⇒ weight swelling, feeling short of breath

⇒ fever, chills, body aches, flu symptoms.

Less serious side effects include:
⇒ cough
⇒ dizziness, feeling tired, depression
⇒ headache, blurred vision
⇒ diarrhea, constipation, stomach pain
⇒ mild skin rash, sweating.

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Drug Cautions and Warnings Lisinopril + Hydrochlorothiazide

What should be known before using lisinopril + hydrochlorothiazide?

Before using this medication, tell your doctor if you are allergic to lisinopril, hydrochlorothiazide, benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), moexipril (Univasc), quinapril (Accupril), ramipril (Altace) , trandolapril (Mavik), sulfa drugs, or other medications.

Tell your doctor if you have diabetes (high sugar levels) and you are taking aliskiren (Tunjukna, in Amturnide, Tekamlo, Tesorna HCT). Your doctor may ask you to stop taking lisinopril and hydrochlorothiazide if you have diabetes and are also taking Aliskiren. Tell your doctor and pharmacist what prescription or non-prescription drugs, vitamins, nutritional supplements, and herbal products you are taking. Be sure to name one of the following: aspirin and nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin), indomethacin (Indocin), and naproxen (Aleve, Naprosyn); barbiturates such as phenobarbital (Luminal, Solfoton); cholestyramine (Questran); colestipol (Colestid); digoxin (Lanoxin); insulin or oral medications for diabetes; lithium (Eskalith, Lithobid); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); other diuretics; other medications for high blood pressure; pain medication; and potassium supplements. Dokder can change the dose of your medication or monitor your side effects.

Tell your doctor if you are being treated with desensitization (a process to reduce reactions to allergens) and if you have or have ever had allergies. asthma; diabetes; gout; High cholesterol; collagen vascular diseases such as lupus or scleroderma (a condition in which extra tissue grows on the skin and some organs); heart failure; any condition that causes you to urinate less than usual; stroke or 'mini-stroke'; heart, kidney, or liver disease; and angioedema, a condition that causes difficulty swallowing or breathing and painful swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs.

Tell your doctor if you plan to become pregnant or breastfeeding. If you are having surgery, including dental surgery, tell your doctor or dentist that you are taking lisinopril and hydrochlorothiazide. Ask your doctor about using alcoholic beverages that are safe while you are taking lisinopril and hydrochlorothiazide. Alcohol can make the side effects of lisinopril and hydrochlorothiazide worse.

Diarrhea, vomiting, not drinking enough fluids, and sweating profusely can all cause a drop in blood pressure, which can lead to fainting.

Lisinopril and hydrochlorothiazide can cause dizziness and fainting when you get up too quickly from a lying position. It is more common when you first start taking lisinopril and hydrochlorothiazide. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

Is lisinopril + hydrochlorothiazide safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

This drug is included in the risk of pregnancy category D according to the US Food and Drug Administration (FDA). The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

There are not adequate studies in women to determine infant risk when using this medicine during breastfeeding. Consider the potential benefits against potential risks before taking this medication while breastfeeding.

Lisinopril + Hydrochlorothiazide Drug Interactions

What medicines may interact with lisinopril + hydrochlorothiazide?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

• Digoxin, dofetilide, or ketanserin can increase the risk of abnormal heart disease
• Everolimus or sirolimus because the risk of angioedema can increase
• Eplerenone, potassium preparations, potassium-sparing diuretics (such as triamterene), salt substitutes containing potassium, or trimethoprim because of the increased risk of high potassium levels.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) (such as celecoxib, ibuprofen, indomethacin) because they can decrease the effectiveness of lisinopril / hydrochlorothiazide and increase the risk of kidney problems.
• Adrenocorticotropic hormone (ACTH), barbiturates (such as phenobarbital), corticosteroids (such as prednisone), dextran sulfate, diazoxide, diuretics (such as furosemide), narcotic pain medicine (such as codeine), or other high blood pressure medications because the risk of low blood pressure can increase.
• Aliskiren or angiotensin receptor blockers (ARBs) (such as losartan) because of the risk of some side effects (eg kidney problems, high potassium levels, low blood pressure) can increase.
• Gold-containing drugs (such as sodium aurothiomalate) because flushing, nausea, vomiting, and low blood pressure can occur
• Cholestyramine, colestipol, or salicylates (such as aspirin) because they can decrease the effectiveness of lisinopril / hydrochlorothiazide
• Lithium or thiopurines (eg azathioprine) due to increased risk of side effects by lisinopril / hydrochlorothiazide
• Insulin or other diabetes drugs (such as glyburide) may decrease their effectiveness by lisinopril / hydrochlorothiazide

Can food or alcohol interact with lisinopril + hydrochlorothiazide?

Certain drugs should not be used with meals or around meals at certain foods or foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with lisinopril + hydrochlorothiazide?

The presence of other medical problems may affect the use of this drug. Make sure you tell your doctor if you have any other medical problems, especially:

Angioedema (swelling of the face, lips, tongue, throat, arms, or legs), this risk can recur
⇒ anuria (unable to pass stool)
⇒ diabetic patients who are also taking Aliskiren (Tesorna®)
⇒ hereditary or idiopathic angioedema
⇒ patients who have kidney problems and are also taking Aliskiren (Tesorna®)
⇒ allergy drugs Sulfa (eg, sulfamethoxazole, Bactrim®, Septra®) should not be used in patients with this condition
⇒ asthma. May increase the chance of having an allergic reaction.
⇒ collagen vascular disease (autoimmune disease) together with kidney disease - Increased risk of blood problems.

Congestive heart failure, the use of this drug can cause kidney problems.
⇒ diabetes
⇒ kidney problems. Increased risk of potassium levels in the body becoming too high.
⇒ electrolyte imbalance (for example, low magnesium, potassium, or sodium in the blood)
⇒ fluid imbalance (caused by dehydration, vomiting, or diarrhea)
⇒ glaucoma, secondary closed or angle
⇒ gout
⇒ heart or blood vessel disease (eg, aortic stenosis, hypertrophic cardiomyopathy)
⇒ hypercalcemia (high calcium in the blood)
⇒ hypercholesterolemia (high cholesterol in the blood)
⇒ liver disease
⇒ acute myopia (changes in the eyeball causing vision problems)
⇒ systemic lupus erythematosus (SLE). Use with care. Can make conditions worse.

Lisinopril + Hydrochlorothiazide overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (115) or immediately to the nearest hospital emergency department.

Symptoms of an overdose include:

⇒ dizzy
⇒ passed out
⇒ blurred vision
⇒ dry mouth
⇒ thirsty

⇒ tired
⇒ sleepy
⇒ restless
⇒ confused
⇒ convulsions
⇒ muscle pain or cramps
⇒ frequent urination
⇒ stomach ache
⇒ vomiting
⇒ fast or pounding heart rate

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.