Table of contents:
- What Drug Neomycin?
- What is Neomycin for?
- How to use Neomycin?
- How is Neomycin stored?
- Neomycin dosage
- What is the Neomycin dosage for adults?
- What is the dosage of Neomycin for children?
- In what dosage is Neomycin available?
- Neomycin side effects
- What side effects can be experienced due to Neomycin?
- Neomycin Drug Warnings and Cautions
- What should be known before using Neomycin?
- Is Neomycin safe for pregnant and lactating women?
- Neomycin Drug Interactions
- What medicines may interact with Neomycin?
- Can food or alcohol interact with Neomycin?
- What health conditions can interact with Neomycin?
- Neomycin overdose
- What should I do in an emergency or overdose?
- What should I do if I miss a dose?
What Drug Neomycin?
What is Neomycin for?
Neomycin is a drug used to reduce the risk of infection after certain intestinal surgeries. Neomycin belongs to a class of drugs known as aminoglycoside antibiotics. It works by stopping the growth of bacteria in the intestines.
Neomycin can also be used in conjunction with a special diet program to treat certain serious brain problems (hepatic encephalopathy). This condition is caused by too much of a certain natural substance (ammonia). Normally, the liver gets rid of ammonia, but liver disease can cause too much ammonia to build up in the body. This medication helps treat encephalopathy by killing certain gut bacteria that make ammonia.
This antibiotic treats only bacterial infections. This medicine will not work for viral infections (such as cold, flu). The unnecessary use of antibiotics or the abuse of any antibiotics can cause their effectiveness to decrease.
How to use Neomycin?
Take this medication as prescribed by your doctor.
To reduce the risk of infection after bowel surgery, this medication is usually used for 3 or 4 doses a day before surgery, or as directed by your doctor. Carefully follow your doctor's instructions for dietary restrictions and use of this medicine or other products before surgery.
To treat hepatic encephalopathy, this medication is usually used four times daily for 5-6 days, or as directed by your doctor.
Dosage is based on your medical condition and response to treatment. To reduce the risk of hearing loss and other side effects, take this medication at the lowest effective dose for the shortest possible time. Do not increase your dose, take it more frequently, or use it for a longer time than recommended. The manufacturer recommends that this drug should not be used for more than 2 weeks during any treatment period.
If you are taking this medication for encephalopathy, use it regularly for optimal benefit. To help you remember, drink it at the same times each day. Tell your doctor if your condition does not improve or gets worse.
Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.
How is Neomycin stored?
This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.
Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.
Neomycin dosage
The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.
What is the Neomycin dosage for adults?
Usual Adult Dose for Intestinal Surgery Preparation
1 g orally every hour for 4 doses followed by 1 g every 4 hours for 5 doses.
Alternative dose: 6 g / day orally divided every 4 hours for 2 to 3 days.
Usual Adult Dose for Hepatic Encephalopathy
4 to 12 g / day orally divided every 4 to 6 hours for 5 to 6 days.
Usual Adult Dose for Hepatic Coma
4 to 12 g / day orally divided every 4 to 6 hours for 5 to 6 days.
Usual Adult Dose for Diarrhea
3 g / day orally divided into 4 doses
What is the dosage of Neomycin for children?
Usual Children's Dose for Intestinal Preparation
The safety and efficacy of neomycin in children younger than 18 years have not been established. However, the use of neomycin may be appropriate in some situations.
Less than 1 month: 50 mg / kg / day orally divided every 6 hours
1 year to 18 years: 50 to 100 mg / kg / day orally divided every 6 hours.
Usual Children's Dose for Hepatic Encephalopathy
The safety and efficacy of neomycin in children younger than 18 years have not been established. However, the use of neomycin may be appropriate in some situations.
1 month to 18 years: 50 to 100 mg / kg / day orally divided every 6 to 8 hours for 5 to 6 days.
Usual Children's Dose for Hepatic Coma
The safety and efficacy of neomycin in children younger than 18 years have not been established. However, the use of neomycin may be appropriate in some situations.
1 month to 18 years: 50 to 100 mg / kg / day orally divided every 6 to 8 hours for 5 to 6 days.
Usual Children's Dose for Diarrhea
The safety and efficacy of neomycin in children younger than 18 years have not been established. However, the use of neomycin may be appropriate in some situations.
Less than 1 month: 50 mg / kg / day orally divided every 6 hours.
1 year to 18 years: 50 mg / kg / day orally divided every 6 hours for 2 to 3 days
In what dosage is Neomycin available?
Tablet, Oral: 500 mg
Solution, Oral: 125 mg / 5 mL
Neomycin side effects
What side effects can be experienced due to Neomycin?
Get emergency medical help if you have any of these signs of an allergic reaction: nausea, vomiting, sweating, hives, difficulty breathing, swelling of your face, lips, tongue, or throat, or feel like you might pass out.
Stop using Neomycin and call your doctor if you have any of the following serious side effects:
- hearing problems, ringing in your ears, or a feeling of fullness in your ears
- a spinning sensation, nausea, a feeling like you might pass out
- loss of balance or coordination, difficulty walking
- numbness or tingling feeling under your skin
- muscle twitching, spasms
- urinating less than usual or not at all
- drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting
- swelling, weight gain, feeling short of breath
- Weak breathing or shallow breathing or
- severe stomach cramps diarrhea that is watery or bloody
Less serious side effects may include:
- mild nausea, vomiting
- mild diarrhea
Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.
Neomycin Drug Warnings and Cautions
What should be known before using Neomycin?
Before using neomycin,
- tell your doctor and pharmacist if you are allergic to neomycin or any other medications
- tell your doctor and pharmacist about any prescription and nonprescription drugs you are taking, including vitamins
- tell your doctor if you have or have ever had kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using neomycin, call your doctor.
Is Neomycin safe for pregnant and lactating women?
There are no adequate studies regarding the risks of using this drug in pregnant or nursing women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category D according to the US Food and Drug Administration (FDA).
The following references the pregnancy risk categories according to the FDA:
- A = No risk,
- B = not at risk in several studies,
- C = May be risky,
- D = There is positive evidence of risk,
- X = Contraindicated,
- N = Unknown
There are not sufficient studies in women to find out the risk to the baby when the mother takes this drug during breastfeeding. Consider the potential benefits and potential risks before taking this medication during breastfeeding.
Neomycin Drug Interactions
What medicines may interact with Neomycin?
Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval
Neomycin can harm the kidneys, and this effect is increased if you are also taking certain other drugs that are harmful to the kidneys. Before using neomycin, tell your doctor about all other medicines you use. Many other drugs (including some drugs on the market) can be harmful to the kidneys.
Before you use neomycin, tell your doctor if you are using other antibiotics, such as:
- amikasin (amikin)
- amphotericin-B (Amphotec)
- bacitracin (Baci IM)
- colistimethate (Coly Mycin M)
- gentamicin (Garamycin)
- kanamycin (Kantrex)
- paromomycin (Humatin, Paromycin)
- polymyxin B sulfate
- penicillin V (PC Pen VK)
- streptomycin
- tobramycin (Nebcin, Tobi) or
- vancomycin (Vancocin, Vancoled).
Tell your doctor about all other medicines you use, especially:
- cisplatin (Platinol)
- digoxin (digitalis, Lanoxin, Lanoxicaps)
- methotrexate (Rheumatrex, Trexall)
- vitamin B-12
- antiviral drugs such as adefovir (Hepsera), cidofovir (Vistide), or tenofovir ()
- blood thinners such as warfarin (Coumadin, Jantoven)
- botulism toxin drugs (Botox, Dysport, Myobloc, Xeomin, and others) or
- diuretics (water pills) such as bumetanide (Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), or torsemide (Demadex)
Can food or alcohol interact with Neomycin?
Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.
What health conditions can interact with Neomycin?
The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems, such as:
- Kidney illness
- myasthenia gravis or
- Parkinson's disease
Neomycin overdose
What should I do in an emergency or overdose?
In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.
What should I do if I miss a dose?
If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.
