Iopromide: functions, dosage, side effects, how to use

What drug Iopromide?

What is iopromide used for?

Iopromide is a type of injection drug. This drug belongs to the type of drug radiographic contrast agent which is used for the following:

• Cerebral arteriography and peripheral arteriography
• Coronary arteriography and left ventriculography, visceral arteriography and aortography
• Peripheral venography
• Excretory urography

This medication is generally used to help diagnose or find problems with the brain, heart, head, blood vessels, and other parts of the body. This drug is an iodinated contrast agent. Contrast agents are used to create clear images of different parts of the body during medical procedures such as CT scans and angiography.

Iopromide is only used or under the direct supervision of a doctor. Therefore, this drug is included in prescription drugs because you cannot buy it freely in pharmacies.

How is iopromide used?

If you want to use this drug, you must know how to use it, as follows:

• This medication cannot be used alone at home, therefore it will be administered by a doctor or other health professional. This medicine will be given to you or your child in the hospital. Iopromide is given by injection.
• Before using this medicine you must drink extra fluids because you will urinate more while using Iopromide. This can help prevent kidney problems.
• The dose that your doctor gives you is usually adjusted to your health condition.

How is iopromide stored?

The following are procedures for storing drugs that you should pay attention to:

• This medication is best stored at room temperature, away from direct light and damp places.
• Do not store in the bathroom and do not freeze in the freezer.
• Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist.
• Keep all medicines away from children and pets.
• Keep this medication away from exposure to sunlight and direct light.

If you are no longer using this medicine, you must dispose of this medicine in a manner that is safe for environmental health. Do not flush medicines down the toilet or down the drain unless instructed to do so.

Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or staff from your local waste disposal agency about how to safely dispose of your product.

Iopromide dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the iopromide dosage for adults?

Adult dosage for contrast-enhanced computerized tomography

• 300 mg iodine / ml.
• Head: 50-200 ml;
• max dose for procedure: 200 ml.
• Body: 50-200 ml as bolus injection, rapid infusion or both (usual dose for infusion: 100-200 ml);
• max dose for procedure: 200 ml.
• Max iodine dose: 86 g.

Adult dosage for excretory urography

• Adults: 300 mg iodine / ml.
• Max dose for the procedure: 100 ml.
• Max iodine dose: 86 g.

Adult dosage for peripheral venography

• Adults: 240 mg iodine / ml.
• Max dose for the procedure: 250 ml.
• Max iodine dose: 86 g.

Adult dosage for aortography and visceral angiography

• Adults: 370 mg iodine / ml.
• Max dose for the procedure: 225 ml.
• Max iodine dose: 86 g.

Adult dosage for cerebral arteriography

• Adults: 300 mg iodine / ml.
• Max dose for the procedure: 150 ml.
• Carotid artery: 4-12 ml.
• Vertebral artery: 4-12 ml.
• Aortic arch injection: 20-50 ml.
• Max iodine dosage: 86 g.

Adult dosage for coronary arteriography and left ventriculography

• Adults: 370 mg iodine / ml.
• Max dose for the procedure: 225 ml.
• Leaving coronary: 3-14 ml.
• Coronary right: 3-14 ml.
• Left ventricle: 30-60 ml.
• Max iodine dose: 86 g.

Adult dosage for Intra-arterial digital subtraction angiography

• Adults: 150 mg iodine / ml.
• Max dose for the procedure: 250 ml.
• Carotid artery: 6-10 ml.
• Vertebral: 4-8 ml.
• Aorta: 20-50 ml.
• The main branches of the abdominal aorta: 2-20 ml.
• Max iodine dose: 86 g.

Adult dosage for peripheral arteriography

• Adults: 300 mg iodine / ml.
• Max dose for the procedure: 250 ml.
• Arteries need flow to be injected.
• Subclavian or femoral artery: 5-40 ml.
• Aortic bifurcation for distal states: 25-50 ml.
• Max iodine dosage: 86 g.

What is the iopromide dosage for children?

Child dosage for contrast agents for cardiac chambers and associated arteries

• Children:> 2 years: 370 mg iodine / ml with 1-2 ml / kg.
• Max dose for the procedure: 4 ml / kg.

Child dosage for contrast-enhanced computerized tomography

• Children:> 2 years: 300 mg iodine / ml with 1-2 ml / kg.
• Max dose for the procedure: 3 ml / kg.

Child dosage for excretory urography

• Children:> 2 years: 300 mg iodine / ml with 1-2 ml / kg.
• Max dose for the procedure: 3 ml / kg.

In what dosage is iopromide available?

Solution, injection: 240 mg / ml, 300 mg / ml and 370 mg / ml

Iopromide side effects

What side effects can I experience due to iopromide?

Use of this drug can also increase the risk of side effects. Immediately consult a doctor or nurse if the following side effects occur.

• bleeding, blistered skin, burning, cold, discoloration of skin, feeling pressure, hives, infection, inflammation, lump, numbness, pain, rash, redness, scarring, pain, stinging, swelling, tingling, rotting, or warm over the injection site
• chest pain
• feel faint, lightheadedness
• feeling hot
• redness of the skin, especially of the face and neck
• frequent urination
• headache
• sweating

Very rare side effects occur:

• bloating or swelling of the face, arms, hands, lower legs
• bluish lips or skin
• chest tightness
• seizures
• cough
• decreased frequency of urination
• difficult or painful urination or pain when urinating
• difficulty breathing
• excessive thirst
• fever or chills
• nausea or vomiting
• wheezing or wheezing breath
• pain or discomfort in the arms, jaw, back, or neck
• pale skin at the injection site
• irregular heartbeat
• tingling in the hands or feet
• unusual fatigue
• weight gain or loss

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Iopromide Drug Warnings and Cautions

What should be known before using iopromide?

Before using this medication, tell your doctor the following:

• Any health conditions you have or are currently having.
• The drugs you use, ranging from herbal medicines, prescription drugs, non-prescription drugs, multivitamins, and dietary supplements.
• If you are pregnant, planning to become pregnant, or breastfeeding

Is iopromide safe for pregnant and lactating women?

There are no adequate studies to determine the risks of using the medication in women during pregnancy or breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category B according to the Food and Drug Administration (FDA) or the equivalent of the Food and Drug Administration (BPOM) in Indonesia. The following references the pregnancy risk categories according to the FDA:

• A = no risk,
• B = no risk in several studies,
• C = there may be a risk,
• D = tested positive for risk,
• X = contraindicated,
• N = unknown

There have not been adequate studies on the use of this drug in women to determine the risk to the fetus when using the drug during breastfeeding. Consider the benefits and risks before using this medicine during breastfeeding.

Iopromide Drug Interactions

What medicines may interact with iopromide?

Drug interactions can change the performance of the drug or increase the risk of serious side effects. Not all possible drug interactions are listed in this article. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Using iopromide with any of the following medicines is not recommended. Your doctor may not prescribe this medicine to you or will replace some of the drugs you are already taking.

• Metformin

Using Iopromide with the drugs below may increase the risk of side effects, but in some cases, a combination of these two drugs may be the best treatment. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.

• Iocetamic Acid
• Iopanoic Acid
• Ipodate
• Tyropanoate Sodium

Can food or alcohol interact with iopromide?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with iopromide?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• allergic rhinitis (hay fever)
• allergic to contrast agents
• allergies to food
• allergic to iodine
• asthma. Use with care. May increase the risk of an allergic reaction
• blood clotting problems (eg phlebitis, thrombosis)
• heart or blood vessel disease
• hyperthyroidism (overactive thyroid)
• pheochromocytoma (adrenal problem)
• sickle cell anemia (inherited blood disorder). Use with care. It might make things worse.
• vascular disease
• congestive heart failure
• dehydration
• diabetes
• Kidney illness
• multiple myeloma (plasma cell cancer)
• paraproteinemia (high amounts of paraproteins in the blood). May increase the risk of developing kidney failure.
• dehydration (caused by prolonged fasting or use of laxatives). Should not be given to pediatric patients with this condition.
• homocystinuria (genetic disease). Patients with this condition should not undergo angiography because of the increased risk of developing blood clotting problems.
• kidney disorders. Use with care. Side effects will increase due to sluggish removal of drug remnants from the body.

Iopromide overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.