Insulin glulisine: functions, dosage, side effects, how to use it

Uses of Insuline Glulisine

What is insulin glulisine?

Insuline glulisine is a drug given to patients with type 1 diabetes. Those with type 1 diabetes have a condition in which the body produces little, or even zero, insulin so that it is unable to control the amount of blood sugar circulating in the blood. Glulisine insulin is also used as a medicine for people with type 2 diabetes.

In patients with type 1 diabetes, insulin glulisine is usually used in conjunction with other types of insulin unless an insulin pump is used. Meanwhile, in patients with type 2 diabetes, insulin glulisine is used in conjunction with oral medication.

Glulisine insulin is insulin that belongs to the type long acting or also known as rapid acting insulin. That is, this insulin starts working 15 minutes after consumption. Glulisine insulin reaches its peak working period after 30-90 minutes and will last for 3-5 hours.

Rules for using insulin glulisine

Glulisine insulin is available as a liquid that is injected into the subcutaneous (lower layer of the skin). Insulin glulisine is usually injected at 15 minutes before a meal or within 20 minutes after starting the eating process. When injecting insulin glulisine, give it a different place each time you inject it. Do not inject in the same place twice in succession as this can cause skin problems (lipodystrophy).

If you are taking this medication with an insulin pump, do not mix it with other types of insulin. Change the infusion pump, catheter, and syringe every other day, as well as any remaining insulin in the insulin tube. Do not use a pen or syringe at the same time even after changing the needle. Sharing needles increases the risk of infection and disease transfer from one body to another.

How to store insulin glulisine

Read all instructions on the instruction sheet carefully. Store insulin in its original container (don't move it). Protect from heat and direct sunlight. Do not put insulin from the vial into the injection if it is not going to be used right away.

For insulin that has not been opened, store it in the refrigerator at a temperature of 2-8 degrees Celsius.

Don't freeze insulin. Throw out frozen insulin and don't use it even when it's liquid again. When opened, store at less than 25 degrees Celsius and use within 28 days. Meanwhile, for the injection pen storage, remove the needle when storing. Do not use the medicine if it looks cloudy, changes color, or has other particles in it.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

The dose given depends on each patient's needs.

Adult dosage for patients with type 1 diabetes:

• The total daily insulin requirement is 0.5-1 unit / kg / day
• For intravenous use, dissolve to a concentration of 0.05-1 unit / mL in normal brine for intravenous systems using a PVC bag

Adult dosage for patients with type 2 diabetes:

• Combine with insulin intermediate-acting or long-acting basal insulin or anti–diabetics agent the other for prandial insulin
• For intravenous use, dissolve to a concentration of 0.05-1 unit / mL in normal brine for intravenous systems using a PVC bag.

Dosage for children with type 1 diabetes:

This insulin can be given to children who are at least four years old or older with the same dosage as in adult patients with type 1 and type 2 diabetes.

Side effects

What side effects may arise from using insuline glulisine?

Seek emergency medical help immediately if you experience signs of insulin allergy: redness or swelling in the area where the injection was given, rash all over your body, difficulty breathing, fast heartbeat, feeling like you might pass out or swelling in your tongue or throat.

Insulin can indeed provide side effects in line with the properties it provides. The following are some of the common side effects that you should consult your doctor immediately, namely:

• Restless
• Blurred vision
• Seizures
• Pain
• Difficulty
• Cold and pale skin
• Fast heart rate
• Runny nose
• Unnatural fatigue
• Loss of consciousness

Some of the side effects of insulin glulisine may occur but do not require serious attention. These side effects will disappear on their own as the body adjusts to the drug. Talk to your doctor about other side effects that may arise.

Warnings and Precautions

What should I know before using insulin glulisine?

• Tell your doctor about allergic reactions to any medications you have, including insulin glulisine.
• Tell your doctor about all medicines you take. Other drugs that you are taking may cause drug interactions.
• Tell your doctor about any medical history you have or are suffering from, especially heart failure, kidney problems, fluid retention
• Glulisine insulin can cause hypoglycemia when taken with other diabetes medications, skipping meals, or excessive physical activity. It is best to avoid doing jobs that require high alertness (driving for example) after using this medicine before knowing the reaction in your body.
• Do not mix this insulin with the type of insulin. Glulisine insulin can only be mixed together with NPH insulin. when mixing it, make sure that you withdraw the insulin glulisine first into the syringe before withdrawing the NPH insulin. Do not mix insulin if it is not already being used. Consult with your doctor about the correct way to mix this insulin.

Drug Interactions

What drugs may interact with insulin glulisine?

Insulin can lower blood sugar, even to a fairly low limit. Avoid driving and operating machines that require high concentration after taking insulin before you know how insulin works in your body. Also stay away from alcohol consumption because it can further lower your blood sugar levels and can interfere with the work of your diabetes medication.

Avoid the effects of hypoglycemia with the use of corticosteroids, danazol, diazoxide, diuretics, glucagon, isoniazid, phenothiazine derivatives, somatropine, sympathomimetic agents, thyroid hormones, estrogens, progestins (such as the contraceptive pill), protease inhibitors, and atypical antipsychotics.

Overdose

What happens if you overdose on insulin glulisine?

If you have overdosed on this drug the symptom that appears is hypoglycemia. Overcome by giving sugar drinks to the body. In some cases of hypoglycemia which causes the patient to lose consciousness, treat with glucagon injection through the subcutaneous layer (0.5-1 mg) or intravenous glucose. When the patient is conscious, give extra carbohydrates to prevent fainting again. Call emergency medical help right away (119) if you are in a state of emergency.

What should I do if I forget to have an injection?

Insulin glulisine should be injected within 15 minutes before eating, or 20 minutes after starting the eating process. If you forget, follow the instructions given by your doctor. Do not do two injections to make up for forgetting the previous schedule of injections.