Gliquidone: functions, dosage, side effects, how to use it

What Medicine Gliquidone?

What medicine is Gliquidone?

Maybe you are curious about what drug gliquidone. Gliquidone is a drinking drug that has a tablet form.

This drug belongs to the sulfonylurea class, which is an antidiabetic drug that works by stimulating the body to produce natural insulin from the pancreas.

The main function of gliquidone is to treat diabetes, especially type adult maturity onset or non insulin dependent diabetes mellitus (NIDDM). This type is also known as type 2 diabetes.

This drug is used to control excess blood sugar levels in the body. This drug also helps distribute the supply of sugar to the cells in the body that need it, so that the amount of sugar in the blood is low.

This drug is part of a series of treatments that doctors give to treat your health condition. Usually, the use of this drug goes hand in hand with a healthy diet and regular exercise.

You can use this drug by buying it at a pharmacy, but it must be accompanied by a prescription from a doctor considering this drug is included in the class of prescription drugs.

How do you use gliquidone?

After knowing what drug gliquidone is, of course you should use gliquidone appropriately. There are several things that you must pay attention to, including the following.

• Use this medication according to the instructions given by the doctor via prescription notes.
• The right time to use gliquidone is right after eating.
• If the dose given is still low enough, this medicine may be taken before meals. However, if the dose is high enough, drink it after eating.
• This medicine includes a series of diabetes treatments that will be effective if accompanied by the adoption of a healthy lifestyle.

How to save gliquidone?

Given that gliquidone is the same as other drugs, do you know there is a proper drug storage procedure? The following are things you should pay attention to when storing medicine.

• Store this medication at room temperature, not too hot or too cold.
• Keep this medication away from exposure to sunlight or direct light.
• Also keep this drug away from damp places, such as in the bathroom.
• Do not store medicine in the freezer until it freezes.
• Other brands of this drug may have different storage rules.
• Keep this medication out of reach of children and pets.

If you no longer use this medication, or its validity period has expired, you should throw it away immediately. As with storing medicines, you also have to dispose of medicines according to the proper and safe manner.

This must be done so as not to pollute the environment. For example, medicinal waste should not be mixed with ordinary household waste. Medicinal waste should also not be flushed down toilets or other drains.

If you are unsure about how to dispose of a drug that is appropriate and safe for environmental health, ask your pharmacist or staff from your local waste disposal agency for more information.

Gliquidone dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of gliquidone for adults?

Adult dosage for type 2 diabetes mellitus

• Recommended dose: 15 milligrams (mg) taken before breakfast.
• Your doctor may adjust the dosage after seeing how your body reacts to the initial dose given.
• The dose will be added 15 mg again gradually.
• The dosage you use each day may be as high as 45-60 mg divided into 2-3 daily uses. The distribution of doses does not have to be balanced, but the largest dose should be used in the morning.
• A single dose can be up to 60 mg.
• Maximum daily dose: 180 mg.

What is the dose of gliquidone for children?

The dosage for this drug has not been determined. If you want to give this medication to children, check with your doctor first. Make sure that you know the benefits and risks of using this medicine in children.

In what dosage form is gliquidone available?

Tablet, oral: 30 mg

Gliquidone side effects

What side effects can be experienced due to gliquidone?

If you already understand what drug gliquidone is, you should also study the risk of side effects. As with the use of other drugs, this drug also has a risk of side effects.

When using this drug, of course you should be aware of these risks. The risk of side effects can be mild or serious health conditions.

The side effects that are quite serious due to the use of this drug are:

• Hypoglycemia, which is a condition when the body actually lacks blood sugar due to a drastic decrease.
• Jaundice, characterized by yellow eyes and skin. Usually, this is also a sign of a liver problem.
• Steven-Johnson syndrome, which is a disease condition that causes itching. Usually, this also causes the skin to blister until it peels off.
• Exfoliative dermatitis, which is a reddened layer of skin that peels off in a large area on the body.
• Blood cell disorders.

If you experience serious side effects as mentioned above, you should immediately contact your doctor and get medical care.

Meanwhile, there are also minor side effects that you may experience, such as:

• Headache
• Indigestion such as diarrhea, constipation, nausea, vomiting, or stomach pain.
• Gaining weight for no reason
• Skin rash
• Loss of taste, or any food you eat doesn't taste good.
• The skin becomes more sensitive to sunlight. We recommend that, when using this medicine, wear more closed clothing so that the skin does not come into direct contact with the sun.
• Facial skin tends to be red

When your doctor recommends that you use this drug, of course your doctor has weighed the benefits and risks of using gliquidone for your condition.

Not everyone experiences the above side effects. There may be some side effects not listed above but that you are experiencing. If you have concerns about certain side effects after using gliquidone, consult your doctor or pharmacist.

Gliquidone Drug Warnings and Cautions

What should be known before using the drug gliquidone?

Do you know what you should know before using the drug gliquidone? Here are the things you must understand.

• Tell your doctor if you have an allergy to gliquidone.
• Also tell if you have allergies to other drugs, food, dyes and preservatives, and even allergies to animals.
• Tell your doctor about any medications you are currently using, whether prescription drugs, nonprescription drugs, herbal products, or multivitamins.
• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Tell me about any health conditions you are experiencing or have had, especially type 1 diabetes, ketoacidosis, severe infections, trauma, porphyria, hypersensitivity, pre-diabetic states, and kidney or liver problems.
• If you are going to have an operation, whether major or minor, even if it's only dental surgery, tell your doctor or dentist if you are under the influence of the drug gliquidone.

Is the drug gliquidone safe for pregnant and breastfeeding women?

It is still not determined whether the drug gliquidone is safe to use for pregnant and lactating women, because there is no adequate research on the risks of using the drug in pregnant or breastfeeding women and their babies.

If you want to use this drug while pregnant, consult your doctor first. Ask about the benefits and risks of using this medicine for you and your baby. Only use this medication if the benefits outweigh the risks.

This medicine can pass through breast milk (ASI), and may be accidentally consumed by a nursing infant. Given that gliquidone cannot be used for toddlers and children, you should avoid using this drug while breastfeeding. If it's urgent, you may have to stop breastfeeding for a while.

Gliquidone Drug Interactions

What other medicines may interact with gliquidone?

Drug interactions can change how the drug works or increase the risk of serious side effects that may occur. However, drug interactions may also be one of the best forms of treatment for your condition.

However, not all possible drug interactions are listed in this article. Therefore, keep a list of all the products you use (including prescription and nonprescription medicines and herbal products) and notify your doctor and pharmacist. Do not start, stop, or change the dose of any medicine without your doctor's approval.

Here are some types of drugs that can interact with gliquidone. Among others are:

• ACE inhibitors
• allopurinol
• Analgesics, or drugs used to relieve pain
• Anticoagulants, which are drugs used to inhibit blood clotting
• Beta blockers
• Antifungal drugs such as miconazole
• Cimetidine, which is a drug used to treat digestive problems
• Clofibrate, which is a drug used to lower cholesterol levels in the body
• Antidepressant drugs
• Warfarin, heparin, and coumarin, which are blood thinners. When used together, it can change the blood thinning effect
• Mono-amino oxidase inhibitors (MAOI)
• The hormone testosterone

Meanwhile, the following drugs can reduce the effects of gliquidone so that it can increase your blood sugar levels, including:

• diuretics (loop and thiazide diuretics);
• corticosteroid
• birth control pills or oral contraceptive drugs
• phenytoin
• chlorpromazine

Can food or alcohol interact with the drug gliquidone?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with the drug gliquidone?

Not only drugs and food can interact with gliquidone, health conditions in your body can also affect the use of this drug. Tell your doctor about any other health conditions you have or have experienced, in particular:

• Diabetes mellitus type 1
• Ketoacidosis, in which the body lacks blood sugar, so instead of burning sugar and converting it into energy, the body burns fat into energy, thus forming ketone acids in the body.
• Severe infection
• Trauma
• Another condition that is quite severe, in which the use of gliquidone cannot control the increase in blood sugar in the body.
• Pregnancy and breastfeeding
• Porphyria, also known as vampire disease. This condition occurs because of a genetic disorder that arises from the process of forming heme, or an important part of the protein in red blood cells, occurring imperfectly in the body.
• Hypersensitivity
• Chronic liver or kidney problems
• Lack of adrenal or pituitary hormones

Gliquidone overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department. Overdosage can occur if you take more than you should. Therefore, do not use a dose more than what your doctor has prescribed for you.

What should I do if I miss a dose?

If you forget a dose of this medicine, take the missed dose as soon as possible. However, if it turns out that when you are about to take the missed dose, it is time to tell you to take the next dose, skip the missed dose and return to your usual dosing schedule.

Do not double the dose because a double dose will not guarantee whether you can feel the benefits of the drug gliquidone faster than not doubling it. Also, you do not know whether doubling the dose will not increase the risk of side effects from taking the drug or not.

Always consult your doctor about the dosage of drug use, because the doctor who checks your condition will know more about using the dose that is more appropriate and in accordance with your health condition.