Home Drug-Z Clorazepate: functions, dosage, side effects, how to use it
Clorazepate: functions, dosage, side effects, how to use it

Clorazepate: functions, dosage, side effects, how to use it

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What Drug Clorazepate?

What is clorazepate for?

Clorazepate is a drug commonly used to treat feelings of anxiety, acute alcohol dependence, and seizures.

The clorazepate drug is a type of benzodiazepine drug. This drug acts on the brain and nerves (central nervous system) to produce a calming effect by increasing the effects of a certain natural chemical in the body (GABA).

How do I use clorazepate?

Read the drug's guide and the Patient Information Leaflet provided by the pharmacy, if available, before you get this medication and each time you buy again. If you have questions, ask your doctor or pharmacist.

Take this medication as directed by your doctor. Dosage is based on your age, health condition, and response to therapy.

Use this medication exactly as prescribed. Do not increase the dose, take it more often or take it for a longer period than prescribed because this drug can cause dependence. If used for a long period of time, do not stop suddenly without a doctor's approval. In some conditions it can get worse when this drug is suddenly stopped. The dose can be reduced gradually.

When used long-term, this drug may not work very well and may require a different dosage. Talk to your doctor if this medication stops working optimally.

How do I store clorazepate?

Clorazepate is a drug that is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Clorazepate dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of clorazepate for adults?

For restless feelings, the dosage of clorazepate is:

  • The initial dose is 15 mg orally once a day at bedtime or 7.5 mg orally 2 times a day
  • Maintenance dose 15-60 mg in separate doses
  • The usual dose is 15 mg taken 2 times a day

To treat alcohol dependence, the dosage of clorazepate is:

  • 1st day dosage. 30 mg followed by 30-60 mg in separate doses
  • 2nd day dosage. 45-90 mg in separate doses
  • 3rd day dosage. 22.5-45 mg in separate doses
  • 4th day dosage. 15-30 mg in separate doses

Then gradually reduce the daily dose to 7.5-15 mg. Immediately stop medication therapy when the patient's condition is stable. The total daily recommended dose is 90 mg. Avoid excessively reducing the total amount of the drug in succession.

To treat seizures, the dose of clorazepate is:

  • The initial dose is 7.5 mg orally 3 times a day
  • The maintenance dose is 7.5 mg weekly and should not exceed 90 mg per day

What is the dose of clorazepate for children?

Age of children over 13 years

  • The initial dose is 7.5 mg orally 2 times a day
  • The maintenance dose can be increased per week and should not exceed 60 mg per day

Children less than 13 years of age

  • The initial dose is 7.5 mg orally 3 times a day
  • The maintenance dose can be increased to no more than 7.5 mg per week and not to exceed 90 mg per day

In what dosage is clorazepate available?

The drug availability for clorazepate is 3.75 mg, 7.5 mg, and 15 mg tablets.

Clorazepate side effects

What side effects can be experienced due to clorazepate?

The side effects of clorazepate are:

  • Sleepy
  • Feeling weak, lethargic, and not feeling energized
  • Dizzy
  • Blurred vision
  • Lack of balance or coordination
  • Skin rash
  • Nausea or vomiting
  • Stomach ache
  • Constipation
  • Dry mouth
  • Headache

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Clorazepate Drug Warnings and Cautions

What should be known before using clorazepate?

Before using certain drugs, consider the risks and benefits first. This is a decision you and your doctor will have to make. Some things that you should consider before taking clorazepate are:

  • Allergy. Tell your doctor if you have any unusual or allergic reactions to this or any other medicine. Also tell your doctor if you have any other types of allergies such as to food, coloring, preservatives, or animal allergies.
  • Children. The safety and effectiveness of this drug have not been determined for children.
  • Elderly.To date, studies have not demonstrated a specific problem that will limit the usefulness of clorazepate in the elderly. Elderly patients may require lower doses to help reduce unwanted effects. Please consult a doctor for more information.

Is clorazepate safe for pregnant and lactating women?

There is not yet sufficient information about the safety of using this medicine during pregnancy and breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Clorazepate Drug Interactions

What medicines may interact with clorazepate?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

The use of Clorazepate with any of the medicines below is not recommended. Your doctor may decide not to treat you with this drug or change some of the medicines you take.

- Flumazenil

Using this medication with any of the following medicines is not usually recommended, but may be necessary in some cases. If both drugs are prescribed together, your doctor may change the dose or the frequency with which you use one or both drugs.

  • Alfentanil
  • Amobarbital
  • Anileridine
  • Aprobarbital
  • Buprenorphine
  • Butabarbital
  • Butalbital
  • Carbinoxamine
  • Carisoprodol
  • Chloral Hydrate
  • Chlorzoxazone
  • Codeine
  • Dantrolene
  • Ethchlorvynol
  • Fentanyl
  • Phospropofol
  • Hydrocodone
  • Hydromorphone
  • Levorphanol
  • Meclizine
  • Meperidine
  • Mephenesin
  • Mephobarbital
  • Meprobamate
  • Metaxalone
  • Methadone
  • Methocarbamol
  • Methohexital
  • Mirtazapine
  • Morphine
  • Morphine Sulfate Liposome
  • Omeprazole
  • Orlistat
  • Oxycodone
  • Oxymorphone
  • Pentobarbital
  • Phenobarbital
  • Primidone
  • Propoxyphene
  • Remifentanil
  • Secobarbital
  • Sodium Oxybate
  • Sufentanil
  • Suvorexant
  • Tapentadol
  • Thiopental
  • Zolpidem

Using this medication with any of the medicines below may cause an increased risk of side effects, but using both drugs may be the best treatment for you. If both drugs are prescribed at the same time, your doctor may change the dose or frequency of use of one or both drugs.

  • Amprenavir
  • Ginkgo
  • Perampanel
  • St. John's Wort
  • Theophylline

Can food or alcohol interact with clorazepate?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with clorazepate?

Any other health conditions you have can affect the use of this drug. Some of the conditions that may interact with the drug clorazepate are:

  • Glaucoma
  • Mental illness or depression
  • Abuse of certain drugs
  • Kidney illness
  • Liver disease

Clorazepate overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Clorazepate: functions, dosage, side effects, how to use it

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