Home Drug-Z Cinacalcet: functions, dosage, side effects, how to use it
Cinacalcet: functions, dosage, side effects, how to use it

Cinacalcet: functions, dosage, side effects, how to use it

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Anonim

What medicine Cinacalcet?

What is cinacalcet for?

Cinacalcet is a drug that is often used to treat increased amounts of certain hormones (parathyroid) in people with chronic kidney disease. This drug is also used to treat increased amounts of calcium in people with hyperthyroidism or in people with cancer of the parathyroid glands.

Cinacalcet is a drug that works by reducing the amount of parathyroid hormone, calcium, and phosphorus in your body. Adequate intake of these substances in the body helps prevent you from developing bone disease in the future.

How to use cinacalcet?

Take this medicine after meals or according to the instructions given by your doctor. Don't cut the medicine in half. Always follow your doctor's directions on how to take this drug.

Dosage is based on your medical condition, response to treatment, and laboratory tests. Take this medicine regularly for the most optimal benefits. Remember to take this medication at the same time every day.

How to save cinacalcet?

Cinacalcet is a drug that should only be stored at room temperature. Keep this drug away from direct sun exposure and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Cinacalcet dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the cinacalcet dosage for adults?

To treat secondary hyperparathyroidism, the dose of cinacalcet is:

  • Initial dose: 30 mg once daily orally
  • Maintenance dose: 30 to 180 mg once daily, orally
  • Maximum dose: 180 mg once daily

To treat malignant hyperkalemia, the dosage of cinacalcet is:

  • Initial dose: 30 mg orally twice a day
  • Maintenance dose: 60 mg to 360 mg orally per day
  • Maximum dose: 90 mg four times a day

To treat primary hyperparathyroidism, the dosage of cinacalcet is:

  • Initial dose: 30 mg orally twice a day
  • Maintenance dose: 60 mg to 360 mg orally per day
  • Maximum dose: 90 mg four times a day

What is the dose of cinacalcet for children?

The safety and effectiveness of this drug have not been established in children under 18 years of age.

In what dosage is cinacalcet available?

30 mg, 60 mg, and 90 mg tablets

Cinacalcet side effects

What side effects can be experienced due to cinacalcet?

Some of the most common side effects of using the drug cinacalcet are:

  • Nausea
  • Gag
  • Diarrhea
  • Loss of appetite
  • Muscle ache
  • Chest pain
  • Dizzy
  • Fatigue

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Cinacalcet Drug Warnings and Cautions

What should be known before using cinacalcet?

When deciding to take this drug, you must consider the possible risks. This is up to you and your doctor. Here are some things to consider:

  • Allergy

Tell your doctor if you have ever had an allergy to this or any other medicine. Also tell your doctor if you also have any other allergies such as food, coloring, preservatives, or animals. For over-the-counter products, read ingredients labels or packages carefully.

  • Children

Appropriate studies have not been carried out regarding the relationship of age and the effects of cinacalcet in the pediatric population. Safety and efficacy are unknown.

  • Elderly

Appropriate studies to date have not demonstrated the specific problems of seniors that will limit the benefits of cinacalcet in the elderly.

Is cinacalcet safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is pregnancy risk category C according to the Food and Drug Administration (FDA).

The following FDA reference pregnancy risk categories:
• A = No risk,
B = No risk in some studies,
• C = There may be some risks,
• D = positive evidence of risk,
X = Contraindicated,
• N = unknown.

Cinacalcet Drug Interactions

What medicines may interact with cinacalcet?

Although several drugs should not be taken at the same time, in other cases several drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Taking this drug with any of the following medicines is not recommended, but it may be necessary in some cases. If both drugs are prescribed together, your doctor may change the dose or how often you take one or both drugs.

  • Aripiprazole
  • Clozapine
  • Doxorubicin
  • Eliglustat
  • Fluoxetine

Taking this drug with any of the following medicines may cause an increased risk of side effects, but using both drugs may be the best treatment for you. If both drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

  • Desipramine
  • Itraconazole
  • Ketoconazole

Can food or alcohol interact with cinacalcet?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with cinacalcet?

The presence of other medical problems may affect the use of this drug. Make sure you tell your doctor if you have any other medical problems, especially:

  • bone pain
  • heart disease
  • heart failure
  • heart rate problems
  • hypotension (low blood pressure)
  • Seizures
  • kidney disease. The effect can result in an increased risk of kidney disease due to the slow removal of the drug from the body.

Cinacalcet overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Symptoms of an overdose include:

  • Tingling, or uncomfortable feeling in the lips, tongue, fingers, or feet
  • Muscle pain or cramps
  • Tense muscles in the hands, feet, face, or throat
  • Seizures

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Cinacalcet: functions, dosage, side effects, how to use it

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