Thiamphenicol: functions, dosage, side effects, how to use

Uses

What is thiamphenicol used for?

Thiamphenicol is a drug for treating bacterial infections. Thiamphenicol is a class of antibiotic drugs used to treat typhoid fever (typhoid), paratyphoid fever, Salmonella sp, influenza, meningitis, and pneumonia. This drug is also useful for treating infections in the reproductive organs such as gonorrhea, chlamydia, and so on.

The way thiamphenicol antibiotics work is to stop the growth of bacteria and prevent their spread from moving to other parts of the body. Deliberately taking antibiotics when they are not needed will make your body more susceptible to infection later in life. So, use this medication as directed by your doctor.

Thiamphenicol dosage and side effects of thiamphenicol are detailed below.

How to use the drug thiamphenicol?

Thiamphenicol is a strong drug that must use a doctor's prescription. Therefore, always follow the rules given by your doctor or pharmacist before starting taking this drug.

Make sure you read the medication manual that is listed on the packaging label or the Patient Information Brochure provided by your pharmacy, if any, before you get this medication or each time you buy it again. If you have any questions, consult your doctor or pharmacist.

In general, some rules that you should know before taking the antibiotic thiamphenicol are:

• Thiamphenicol is taken usually once or twice a day, or as directed by your doctor.
• You can take this medication at the same time as food or after food. Drink plenty of water while using this medicine, unless your doctor says otherwise.
• The drug thiamphenicol works best when the amount in your body remains at the same level. Therefore, always make sure the time interval between one dose of drug and the next dose is the same. So as not to forget, you can take this drug at the same hour to optimize treatment.
• Do not crush, chew, or cut the medicine into pieces unless your doctor recommends it.
• The duration of treatment and the dose of thiamphenicol are based on the medical condition and response to treatment.
• Do not double your dose of thiamphenicol if you are late or forget to take it because it can trigger disturbances in the body.
• If you forget to take this drug, take it immediately if the distance to the next consumption is not too close. However, if the next consumption is close, ignore it and do not double the thiamphenicol dose.
• Continue treatment until the medication wears off even though symptoms disappear after a few days. Stopping treatment too quickly allows bacteria to continue growing, resulting in a re-infection.
• Tell your doctor if your condition doesn't change, gets worse, or if you experience new symptoms. If you think you may have a serious medical problem, get medical help right away.

How to store the drug thiamphenicol

Thiamphenicol is a drug that should be stored at room temperature. Keep this drug away from direct sunlight and damp places. Don't keep it in the bathroom. Don't freeze it.

Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal agency about how to dispose of your product.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of thiamphenicol for adults?

To treat sexually transmitted infections susceptible infections, the dosage of thiamphenicol is:

1.5 grams daily divided into several doses according to doctor's recommendations. The maximum dose is 3 grams per day for severe infections.

To treat gonorrhea, the dosage of thiamphenicol is:

• 2.5 grams per day for 1-2 days

or

• 2.5 grams on the first day followed by 2 grams per day for the next 4 days

What is the dose of thiamphenicol for children?

For susceptible infections, the dosage of thiampohenicol is:

• 30-100 mg / kg body weight / day

In what dosage is thiamphenicol available?

Thiamphenicol is available in the following dosage forms and strengths:

• 250 mg and 500 mg capsules
• 1 gram tablet
• Dissolved medicine (powder)

Overall, the dosage of thiamphenicol will be adjusted to the age, severity of the disease, the patient's health condition, and the body's response to the drug.

There may be several doses of thiamphenicol not listed above. If you are in doubt about the dosage of this drug, please consult a doctor for more information. Your doctor may give you a dose of medicine that suits your condition.

Side effects

What side effects can be experienced due to the use of thiamphenicol drugs?

Thiamphenicol side effects are mild, such as:

• Allergic reactions.
• Nausea, vomiting, stomach pain, mild diarrhea.
• Stiff muscles.
• Joint pain.
• Feelings of restlessness or hyperactivity.
• Unusual or unpleasant taste in the mouth.
• Mild itching or skin rash.
• Vaginal itching or vaginal discharge.

Tell your doctor right away if you experience serious side effects of lhiamphenicol, such as:

• Diarrhea in the form of fluid or blood.
• Fever, chills, pain, flu symptoms.
• Unusual bleeding or bruising (on the nose, mouth, vagina, or rectum), purple or red spots under the skin.
• Seizures.
• Pale or yellowing skin.
• Dark urine.
• Inflammation of the eye nerves.
• Gray baby syndrome in babies.
• Confusion or fatigue.
• Fever, swollen glands, rash and itching, joint pain, or a general feeling of pain.
• Increased thirst, loss of appetite, swelling, weight gain, difficulty breathing, or not passing urine less than usual.
• Severe allergic reactions such as swelling of the face or tongue, burning eyes, sore skin, followed by a red or purple rash that spreads (especially to the face or upper body) and blisters and peeling skin.

The possible side effects of thiamphenicol vary in each patient. So, not everyone experiences these side effects of thiamphenicol. Not everyone experiences the top thiamphenicodil side effects.

There may be some side effects of thiamphenicol not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist

Precautions & Warnings

What should be known before using thiamphenicol?

Before using the drug thiamphenicol, it is important that you consider all the benefits and risks of this drug. The reason is, the drug Thiamphenicol should not be used carelessly. Some things that are important for you to know before using the clindamycin drug are:

Allergy

Tell your doctor if you have had an allergic reaction or unusual symptoms from using this medicine or other medicines. Also tell your healthcare professional if you have any other types of allergies, such as food, coloring, preservatives, or animals. For over-the-counter medications, read the label or package carefully.

Children

Research on this drug has only been conducted in adults, and there is no specific information comparing the benefits of this drug for children up to 12 years of age with benefits for other age groups. Always consult the safety of this medicine if used for children.

Elderly

Many drugs have not been studied especially in the elderly. So, it is not clear whether this drug is safe or not when consumed by the elderly. Although there is no specific information comparing the benefits of this drug for the elderly with other age groups, it is hoped that this drug does not cause different side effects for the elderly and for the young.

Pregnant and breastfeeding

When you are planning to become pregnant or are breastfeeding, you should only take medication based on a doctor's recommendation.

Any other drugs you are currently taking

It is possible that this drug could interact with other drugs that you are currently taking. These drug interactions can occur with the use of prescription, nonprescription, and herbal drugs. So, always consult a doctor first before using this drug.

There may be other things not mentioned above. If you have other questions, please consult a doctor for more information. The doctor may provide more complete information, including the dosage, safety, and interactions of this drug. Listen carefully to all the information explained by the doctor so that the treatment you are doing runs optimally.

Is thiamphenicol safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

This drug is included in the risk of pregnancy category B according to the Food and Drug Administration (FDA) in the United States, which is equivalent to the POM in Indonesia.

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

It is not known whether this drug can be absorbed by breast milk or could harm the baby. Do not use this medication without telling your doctor if you are breastfeeding.

In essence, don't forget to always consult a doctor first before taking the antibiotic thiamphenicol if you are pregnant, planning to become pregnant, or are breastfeeding.

Interaction

What medicines can interact with thiamphenicol?

Thiamphenicol may interact with other medications you are currently taking by changing the way they work or increasing the risk of serious side effects.

To avoid possible drug interactions, you should keep a list of all the drugs you use (including prescription drugs, non-prescription drugs, and herbal products) and tell your doctor and pharmacist.

The use of thiamphenicol drugs together with the drugs listed below is generally not recommended, but may be needed in some cases. If the two drugs are prescribed together, your doctor may change the dose or how often one or the other drug is used.

• Tolbutamide
• Phenytoin
• Dicoumarol
• Other drugs that are metabolized in the liver

There may be some medicines not listed above. If you are in doubt about the interaction of this drug with other drugs that you are currently taking, please consult your doctor for more information. Your doctor may prescribe other medications that are appropriate for your condition.

For safety reasons, you should never try to start, stop, or change the dose of any medicine without your doctor's approval.

Can food or alcohol interact with drugs?

Certain drugs cannot be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your doctor.

Are there any diseases that can interact with the drug thiamphenicol?

Thiamphenicol may interact with your health condition. These interactions can worsen your health condition or even change how the drug works. Therefore, it is important for you to always tell your doctor or pharmacist about any health conditions you currently have. Some of the health conditions that may interact with the drug thiamphenicol are:

• Hypersensitivity.
• Pre-existing bone marrow depression.
• Impaired kidney function.
• Atopic syndrome.
• Liver disfunction.
• Meningitis.

There may be several health conditions not listed above. If you are in doubt about your health condition, then don't hesitate to consult a doctor. Your doctor may prescribe other medications that are appropriate for your condition.

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (118) or immediately to the nearest hospital emergency department.

Some of the most common symptoms of a drug overdose include:

• Nausea.
• Gag.
• Dizzy.
• Lost balance.
• Numbness and tingling
• Seizures.

There may be some signs and symptoms of a drug overdose not listed above. If you have any doubts regarding this, please consult a doctor for more information.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is near the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.