Table of contents:
- What Drug Repaglinide?
- What is repaglinide for?
- How do I use repaglinide?
- How do I store repaglinide?
- Repaglinide dosage
- What is the dose of repaglinide for adults?
- What is the dose of repaglinide for children?
- In what dosage is repaglinide available?
- Repaglinide side effects
- What side effects can be experienced due to repaglinide?
- Repaglinide Drug Warnings and Cautions
- What should be known before using repaglinide?
- Is repaglinide safe for pregnant and lactating women?
- Repaglinide Drug Interactions
- What medicines might interact with repaglinide?
- Can food or alcohol interact with repaglinide?
- What health conditions can interact with repaglinide?
- Repaglinide overdose
- What should I do in an emergency or overdose?
- What should I do if I miss a dose?
What Drug Repaglinide?
What is repaglinide for?
Repaglinide is used to treat type 2 diabetes. Repaglinide can be used alone or in combination with other medicines to control high blood sugar with a diet and exercise program. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and problems with sex organ function. Diabetes control can reduce the risk of heart disease or stroke. Repaglinide stimulates the body to produce insulin. Insulin is a natural substance that makes the body use the maximum sugar in your diet.
Repaglinide belongs to a class of antidiabetic drugs, known as meglitinides. It works by stimulating the pancreas to produce insulin, a hormone used to reduce glucose in the blood.
How do I use repaglinide?
Follow the medication instructions provided by your doctor or pharmacist before using the medicine. If you have questions, ask your doctor or pharmacist. Read the patient information leaflet the pharmacist provides before using repaglinide and each time you refill it. If you have any questions, consult your doctor or pharmacist.
Take this medication 15 minutes before meals, usually 2-4 times a day depending on the amount of food or according to your doctor's instructions. Use this medicine a maximum of 30 minutes before eating. You may be able to use it right before eating, if needed. Do not use doses of medication if you are not eating or your blood sugar is low.
The dose given is adjusted to your health condition and response to treatment.
If you are switching anti-diabetes drugs (such as chlorpropamide) to repaglinide, follow your doctor's instructions carefully when stopping your old medication and using this medicine.
For optimal results, use this medication regularly according to your doctor's instructions. Follow the treatment plan, meal plan, and exercise program your doctor has recommended carefully.
Check your blood sugar regularly as directed by your doctor. Follow the progress of the results and tell your doctor. It is very important to determine the correct dosage. Tell your doctor if your blood sugar is too high or too low. Your treatment plan may be changed.
How do I store repaglinide?
This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.
Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.
Repaglinide dosage
The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.
What is the dose of repaglinide for adults?
Dosage for type 2 diabetes for adults:
Patients who have not used oral hypoglycemia or patients with HbA1c or less than 8%: 0.5 mg orally with a meal.
Patients who have used oral hypoglycemia or patients with HbA1c greater than or equal to 8%: 1-2 mg taken with food.
All doses should be used within 15 minutes before eating or a maximum of 30 minutes before eating. If you don't eat, don't use repaglinide. Conversely, if you are increasing the time you eat, you should increase the dose of repaglinide.
What is the dose of repaglinide for children?
There is no prescribed dosage for this drug for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use.
Consult your doctor or pharmacist for more information.
In what dosage is repaglinide available?
0.5 mg tablet; 1mg; 2 mg.
Repaglinide side effects
What side effects can be experienced due to repaglinide?
Seek medical help immediately if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.
Stop using riluzole and call your doctor if you experience serious side effects such as:
- convulsions
- pain in the upper abdomen spreading to the back, nausea and vomiting, fast heart rate
- pale or yellowish skin, dark urine color, fever, confusion, or weakness
- fever, sore throat, and headache with severe blistering, peeling and reddening of the skin
Less serious side effects include:
- runny nose, sneezing, cough, or flu symptoms
- diarrhea, nausea
- back pain, headache
- dizzy
- blurred vision
- bone pain
- hair loss
Not everyone experiences the above side effects. There may be some unspecified side effects. If you have concerns about certain side effects, consult your doctor or pharmacist.
Repaglinide Drug Warnings and Cautions
What should be known before using repaglinide?
Before using certain drugs, consider the risks and benefits first. This is a decision you and your doctor will have to make. For this drug, pay attention to the following:
Allergy
Tell your doctor if you have an unusual or allergic reaction to this drug, or any other medicine. Also tell your doctor if you have any other types of allergies such as to food, coloring, preservatives, or animal allergies. For over-the-counter products, read the labels on the packaging carefully.
Children
Further studies on the relationship between age and the effects of repaglinide in children have not been found. The safety and efficiency of the drug has not been determined.
Elderly
This drug has only been tested in patients with a limited age of 65 years or more has not shown a difference in the problem of side effects. But early symptoms of low blood sugar are not easily seen or do not occur in all older patients. This may increase the chance of low blood sugar during treatment.
Is repaglinide safe for pregnant and lactating women?
There are no adequate studies regarding the risks of using this drug in pregnant or nursing women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).
The following references the pregnancy risk categories according to the FDA:
- A = No risk,
- B = not at risk in several studies,
- C = May be risky,
- D = There is positive evidence of risk,
- X = Contraindicated,
- N = Unknown
Repaglinide Drug Interactions
What medicines might interact with repaglinide?
Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / nonprescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.
Taking this drug with any of the following medicines is not recommended. Your doctor may not prescribe this medicine to you or will replace some of the drugs you are already taking.
- Gemfibrozil
Use of repaglinide with some of the following drugs is not usually recommended, but in some cases it may be necessary. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.
- Abiraterone Acetate
- Balofloxacin
- Besifloxacin
- Ciprofloxacin
- Enoxacin
- Fleroxacin
- Flumequine
- Gatifloxacin
- Gemifloxacin
- Degludec Insulin
- Itraconazole
- Levofloxacin
- Lomefloxacin
- Metreleptin
- Moxifloxacin
- Nadifloxacin
- Norfloxacin
- Ofloxacin
- Pazufloxacin
- Pefloxacin
- Pixantrone
- Prulifloxacin
- Rufloxacin
- Simeprevir
- Sparfloxacin
- Teriflunomide
- Tosufloxacin
Taking repaglinide with the drugs below may increase your risk of side effects. However, in some cases, a combination of these two drugs may be the best treatment. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.
- Acebutolol
- Alprenolol
- Atenolol
- Betaxolol
- Bevantolol
- Bisoprolol
- Bitter Melon
- Bucindolol
- Carteolol
- Carvedilol
- Celiprolol
- Clarithromycin
- Cyclosporine
- Deferasirox
- Dilevalol
- Eltrombopag
- Esmolol
- Fenugreek
- Glucomannan
- Guar Gum
- Iproniazid
- Isocarboxazid
- Ketoconazole
- Labetalol
- Levobunolol
- Linezolid
- Mepindolol
- Methylene Blue
- Metipranolol
- Metoprolol
- Moclobemide
- Nadolol
- Nebivolol
- Nialamide
- Oxprenolol
- Penbutolol
- Phenelzine
- Pindolol
- Procarbazine
- Propranolol
- Psyllium
- Rasagiline
- Rifampin
- Rifapentine
- Selegiline
- Sotalol
- Talinolol
- Telithromycin
- Tertatolol
- Timolol
- Tranylcypromine
- Trimethoprim
Can food or alcohol interact with repaglinide?
Certain drugs should not be used with meals or at certain foods because they can cause drug interactions. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.
What health conditions can interact with repaglinide?
Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:
- infection
- ketones in the blood (diabetic ketoacidosis)
- operation
- trauma
- type 1 diabetes (insulin)
- unusual stress — insulin can be used to control diabetes with this condition
- Kidney illness
- liver disease — high levels of repaglinide can occur in the blood; this can change the amount of drug needed
- underactive adrenal glands
- inactive pituitary gland
- malnutrition
- physical weakness — patients with this condition will usually be exposed to low blood sugar during repaglinide use
Repaglinide overdose
What should I do in an emergency or overdose?
In case of emergency or overdose, contact your local emergency services provider (112) or immediately to the nearest hospital emergency department.
What should I do if I miss a dose?
If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.