Renabetic: function, dosage, side effects, how to use

Use

Renabetic for what?

Renabetic is a drug to control blood sugar which is intended for diabetic patients who are not yet dependent on insulin (non-insulin dependent diabetes mellitus / NIDDM). Its use in conjunction with a proper diet and exercise program can help prevent kidney damage, blindness, nerve problems, amputations, and problems with sexual function. Good diabetes control can also reduce the risk of heart attack or stroke.

Renabetic is an oral drug consisting of the main active ingredient glibenclamide. This drug belongs to the sulfonylurea group. Renabetic works to lower blood sugar by stimulating the release of insulin by the pancreas in your body. Renabetic is not intended for patients who are already dependent on insulin as in patients with type one diabetes.

Renabetic drinking rules

Renabetic is an oral medication that is taken by mouth together with a little drinking water. Renabetic is usually taken once a day at the same time as your meal schedule or as recommended by your doctor.

Some people who need blood sugar control are more likely to get a higher dose and be able to take it twice a day.

Renabetic is a trademark of glibenclamide. Glibenclamide has several other brands besides Renabetic. Do not use or change Renabetic to another brand of glibenclamide without discussing it with your doctor.

Tell your doctor if you have used other diabetes medications, such as chlorpropamide. Your doctor will likely make a dosage adjustment. Do not change your dose or stop medication without discussing it with your doctor. the dose given takes into account your health condition, body response, and other drugs you are taking.

What are the Renabetic storage rules?

This medication is best stored at room temperature, no more than 30 degrees Celsius. Avoid storing this medicine in a place exposed to direct sunlight and hot temperatures. Do not freeze this drug. Do not store this medication in damp places, such as in the bathroom. Renabetic is a trademark of glibenclamide. Other brands of glibenclamide may require different treatments in storage. Read the storage instructions on the medicine packaging. Keep all medicines out of reach of children.

Do not flush this medication in a toilet or drain, unless instructed to do so. Throw this medicine out if it is no longer used or has entered its expiration date. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Renabetic for adults?

• Initial dose: 2.5 mg (use half a tablet)
• Dose adjustment: may be increased by half a tablet every 3 - 5 days until metabolic control is achieved
• Maximum dose: 20 mg per day
• For doses of more than 10 mg per day it needs to be given in two separate doses

What is the dosage of Renabetic for children?

The dosage for children has not been established. This medicine can be dangerous if given to children. Consult your doctor regarding this before giving it to your child.

What is the dosage of Renabetic for the elderly and patients with impaired liver and kidney function?

Initial dose: 1.25 mg per day

Renabetic administration in excess of 10 mg per day should be given in divided doses

In what dosages and preparations is Renabetic available?

Tablet, Oral: 5 mg

Side effects

What side effects can the consumption of Renabetic cause?

Keep in mind that your doctor prescribes certain medications because they rate their benefits as large against the risk of possible side effects. Basically, almost all drugs have side effects, but rarely cause serious reactions in many people.

You may experience nausea, vomiting,heartburn, feeling tight as a common side effect that occurs due to consumption of Renabetic. Hypoglycemia can also occur, especially if you are taking other diabetes medications or don't get enough calories or do strenuous activities that day.

Some of the other side effects that may occur due to the consumption of glibenclamide contained in glibenclamide are as follows:

• Nausea, stomach pain, fever, loss of appetite, dark colored urine, pale stool color, jaundice (yellowing of the skin or eyes)
• Pale, dazed, or limp skin
• Easy bruising or bleeding, reddish or purplish rash
• Headaches, difficulty concentrating, having trouble remembering, feeling lightheaded, hallucinations, fainting, seizures, slow breathing or stopping breathing

You may also get an allergic reaction as a side effect of taking this drug. Tell your doctor right away if you notice signs of a serious allergic reaction, such as itching, reddish rash, swelling of the face / eyes / lips / tongue / throat area, dizziness, and difficulty breathing.

Stop treatment and contact your doctor immediately if you find the symptoms above. Not everyone experiences the side effects that have been described. Not all side effects are listed above. Consult your doctor if you have concerns about the risk of side effects that can occur.

Warnings and Precautions

What should I know before taking Renabetic?

• Tell your doctor and pharmacist if you are allergic to glibenclamide (the active ingredient in Renabetic) or any other medicines. Renabetic may contain other ingredients that have the potential to cause an allergic reaction
• Tell your doctor about your medical history, including past or current illnesses, especially if you have severe kidney problems, liver and heart disease, diabetic coma, have G6PD deficiency (a genetic condition that causes the breakdown of red blood cells to be more fast), hormonal disorders related to the adrenal or thyroid glands
• Tell your doctor all the products you use, including nonprescription drugs, vitamins, and herbal medicines. Some products may interact to decrease how the drug works. A list of interactions can be seen in the next section
• If you are going to have surgery, such as dental surgery, tell your doctor or dentist that you are using Glibenclamide
• The glibenclamide contained in Renabetic can make you more sensitive to sun exposure. Avoid yourself from exposure to the sun for too long and use sun cream and clothes that are sufficient to protect when going out of the house. Call your doctor if you find skin burns or sores
• Tell your doctor if you are planning a pregnancy or are pregnant and need blood sugar control. Your doctor may provide alternative treatment

Is Renabetic safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. Giving this drug is only done if the benefits provided to pregnant or nursing mothers are greater than the risks that might be to the fetus. This drug is in the category C pregnancy risk (possibly risky) according to the United States Food and Drug Administration.

Drug Interactions

What drugs may interact with Renabetic?

Certain drugs cannot be prescribed together because they may cause drug interactions. Drug interactions can change how one drug works or increase the risk of side effects. The following are some of the drugs that may interact with Renabetic:

• Betablockers, such as metoprolol, propranolol, and timolol
• Biguanid diabetes drugs
• Chloramphenicol
• Clofibrate
• Salicylates and tetracycline
• Corticosteroids
• Laxatives
• Estrogen hormone
• Thyroid hormone
• Insulin

Not all possible drug interactions are listed above. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medicine without your doctor's approval.

Overdose

What should I do in an emergency or overdose?

Immediately call for emergency medical assistance (119) or to the emergency room of the nearest hospital if you see signs of an emergency or an overdose of glibenclamide contained in Renabetic. Symptoms of an overdose can include hypoglycemia, which is characterized by body shaking, excessive hunger, decreased consciousness, and seizures.

What if I miss my medication schedule?

If you forget to take medication, take this medicine as soon as you remember. If it is too close to the next schedule, skip the missed dose and continue the dose according to the predetermined schedule. Do not double your dose on a single medication schedule.