Creatinine phosphokinase & bull; hello healthy

Definition

What is creatinine phosphokinase?

Creatinine is a biochemical test that is done to diagnose liver damage. Creatine phosphokinase or Creatine Phosphokinase (CPK) is found in heart muscle, skeletal muscle and brain. The serum CPK concentration will increase when the muscles in the nerve cells are injured. CK levels will increase within 6 hours after injury. If this damage occurs repeatedly, the CK level will increase sharply after 18 hours of injury and return to normal within 2-3 days.

CK is the main enzyme in the heart studied in patients with heart disease. To check the specifications for myocardial lesions, three different CK isoenzymes were tested, including: CK-BB (CK1), CK-MB (CK2), CK-MM (CK3). Since the characteristics of the enzyme metabolism are known to the doctor, the timing, levels and instructions for treatment will be determined.

When should I take creatinine phosphokinase?

This test is done to diagnose injury to the heart (myocardial infarction). This test can also indicate neurological pathologies or diseases of the skeletal muscles. When CPK levels are high, usually skeletal muscle tissue, heart, or brain muscle tissue is injured or stressed. Identifying the type of CPK can help the doctor determine which type of wound you had.

Your doctor will recommend this test, if your doctor needs to:

diagnosing myocardial infarction
diagnosing chest pain
determine muscle breakdown
identify dermatomyositis, muscle inflammation, and other diseases
differentiate between malignant hyperthermia and postoperative infection

Precautions & warnings

What should I know before taking creatinine phosphokinase?

Here are a few factors that affect the test results:

intramuscular injection can increase CPK levels
strenuous exercise or surgery in the near future can also increase CPK levels
people who have high muscle mass also tend to have high CPK levels than others, so that the CPK levels in men are usually higher than in women
young pregnant can reduce levels of CPK concentrations
Some drugs can increase CPK concentrations including wine, amphotericin, ampicillin, some anesthetics, anticoagulants, aspirin, ACE inhibitors, colchicine, dexamethasone, fibrates, furosemide, lidocaine, lithium, morphine, propranolol, statins, and succinylcholine.

Your doctor may order tests to check for myocardial infarction or injury to your muscles. If you have a heart attack, your doctor will check the levels of troponin in your blood. This is another type of protein found in the heart muscle. Recently, the troponin test has been replaced by the CPK test in diagnosing myocardial infarction because the troponin test is sensitive and has high specificity.

Blood tests and other EKGs can also be prescribed. Because CPK might increase your risk of thyroid problems, alcohol abuse, or kidney failure, your doctor will order other tests to check for any disorders you have.

It is very important to understand the warnings and precautions before carrying out this test. If you have any questions, please ask your doctor for more information.

Process

What should I do before taking creatinine phosphokinase?

The doctor will explain the procedure for carrying out this test. The doctor will also discuss the reasons and importance of drawing blood through this vein to diagnose myocardial infarction. There are no restrictions on eating or drinking for you prior to this test.

How does creatinine phosphokinase process?

The doctor will take a sample of your blood and put it in a red-closed tube. Usually a blood sample will be drawn every day for three days then once a week. The doctor will replace the area where the blood sample is drawn. You must follow your doctor's instructions closely to prevent hemolysis. You should record the date and time of the test, which is done intramuscularly. You should also record the date and time when you did the blood test on a special note. This will help you interpret an increase or decrease in the enzyme.

What should I do after taking creatinine phosphokinase?

You should put a bandage on your hand and gently press the area where the injection was taken to stop the blood. If you have any questions about this process, please consult a doctor for more information.

Explanation of the Test Results

What do my test results mean?

Normal result

Total CPK:

adults and parents (men): 55-170 units / L or 55-170 units / L (SI units)
adults and people (women): 30-135 units / L or 30-135 units / L (SI units). Figures are higher after exercise
babies: 68-580 units / L (SI units)

Other Isoenzyme:

CK-MM: 100%
CK-MB: 0%
CK-BB: 0%

Abnormal results

increased CK concentration: pain or injury that affects the heart muscle, skeletal muscle, and brain
increased concentration of CK-BB isoenzymes: diseases of the central nervous system, adenocarcinoma (especially breast and lung), pulmonary embolism
increased levels of CK-MB isoenzymes; acute myocardial infarction, cardiac aneurysm surgery, defibrillation, heart muscle inflammation, ventricular arrhythmias, ischemic heart disease
increased concentration of CK-MM isoenzymes: rhabdomyolysis, muscular dystrophy, muscle inflammation, recent surgery, electromechanical, intramuscular, internal injuries, rapturous delirium alcohol levels, malignant hyperthermia, recent shock, electrical therapy for convulsions, shock, hypokalemia, hypothyroidism, trauma

Depending on the laboratory of your choice, the normal range of this test may vary. Discuss any questions you have about your medical test results with your doctor.