Hyoscyamine: functions, dosage, side effects, how to use

Functions & Usage

What is Hyoscyamine used for?

Hyoscyamine is a medicine to treat various stomach problems / intestinal problems such as cramps and irritable bowel syndrome. This medication is also used to treat other conditions such as problems with bladder control and bowel problems, abdominal cramping pain caused by kidney stones and gallstones, and Parkinson's disease. In addition, Hyoscyamine is also used to reduce the side effects of certain drugs (drugs used to treat myasthenia gravis) and insecticides.

Hyoscyamine works by reducing acid production in the stomach, slowing down the natural movement of the intestines, and relaxing muscles in many organs (eg, stomach, intestines, bladder, kidneys, gall bladder). Hyoscyamine can also reduce the amount of certain body fluids (eg, saliva, sweat). This drug belongs to a class of drugs known as anticholinergics / antispasmodics.

What are the rules for using Hyoscyamine drugs?

Take this medication as prescribed, usually 30-60 minutes before meals, or as directed by your doctor.

Dosage is based on your medical condition and response to therapy. Do not increase your dose or take it more often than prescribed without consulting your doctor. Adults and children 12 years and over should not drink more than 1.5 milligrams in 24 hours. Children 2 to 12 years of age should have no more than 0.75 milligrams in 24 hours. Ask your doctor or pharmacist for more information.

Antacids decrease Hyoscyamine absorption. If you are taking antacids, then take them after eating and take Hyoscyamine before meals; or take Antacids at least 1 hour after taking Hyoscyamine.

Drink plenty of fluids while taking this medicine unless your doctor directs you to do otherwise.

Tell your doctor if your condition persists or gets worse.

How to store Hyoscyamine?

Store at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Precautions & Warnings

What should be considered before using Hyoscyamine drugs?

Before taking Hyoscyamine, tell your doctor and pharmacist:

• If you are allergic to Hyoscyamine, other drugs, or any of the ingredients contained in tablets, capsules, or Hyoscyamine. Ask your doctor or pharmacist for a list of ingredients in these drugs.
• Regarding prescription drugs and non-prescription drugs, vitamins, nutritional supplements, and herbal products that you use or have ever used. Be sure to name one of the following medications: amantadine (Symadine, Symmetrel), amitriptyline (Elavil), chlorpromazine (Thorazine), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), fluphenazine (Haldolixin), haloperidol ), imipramine (Tofranil), medicines containing belladonna (Donnatal), mesoridazine (Serentil), nortriptyline (Pamelor), perphenazine (Trilafon), phenelzine (Nardil), prochlorperazine (Compazine), promazine (Sparine), promethazine ), protriptyline (Vivactil), thioridazine (Mellaril), tranylcypromine (Parnate), trifluoperazine (Stelazine), triflupromazine (Vesprin), trimeprazine (Temaril), and trimipramine (Surmontil). Your doctor may need to change the dose of your medication or may monitor you more carefully so that the side effects you will get are not too big.
• You have to understand that Antacids can interfere with the work of Hyoscyamine, becoming less effective. Take Hyoscyamine 1 hour before or 2 hours after antacids.
• If you have or have ever had glaucoma; heart, lung, liver, or kidney disease; urinary tract or intestinal obstruction; enlarged prostate; ulcerative colitis A condition that causes swelling and injury of the lining of the large intestine and rectum); or myasthenia gravis.
• If you are pregnant, planning to become pregnant, or are breastfeeding. If you become pregnant while taking Hyoscyamine, contact your doctor.
• Talk to your doctor about the risks and benefits of taking Hyoscyamine if you are over 65 years of age. Older adults should not take Hyoscyamine because it is unsafe and may not be as effective as other drugs that can be used to treat the same condition.
• If you are having surgery, including dental surgery, tell your doctor or dentist that you are taking Hyoscyamine.
• You should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how Hyoscyamine effects you.
• Ask your doctor about the safe use of alcohol during your treatment with Hyoscyamine. Alcohol can make the side effects of this drug worse,

Is Hyoscyamine safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This medicine is included in the pregnancy risk category C. (A = No risk, B = No risk in some studies, C = Possible risk, D = There is positive evidence of risk, X = Contraindicated, N = unknown)

Hyoscyamine passes into breast milk and could harm a nursing baby of mothers who are taking this medicine. Do not use this medication without telling your doctor if you are breastfeeding while breastfeeding a baby.

Side effects

What are the possible side effects of Hyoscyamine?

Seek immediate medical help if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Stop using Hyoscyamine and contact your doctor if you experience serious side effects such as the following:

• Diarrhea
• Confusion, hallucinations
• Unusual thoughts or behavior
• A fast, pounding, or uneven heartbeat
• Rash or flushing (feeling warm, reddish, or tingling)
• Sore eyes

Less serious side effects may include:

• Dizziness, drowsiness, feeling nervous
• Blurred vision, headaches
• Sleep problems (insomnia)
• Nausea, vomiting, bloating, heartburn, or constipation
• Change in taste
• Problems with urinating
• Less sweat
• Dry mouth
• Impotence, loss of interest in sex, or difficulty having an orgasm

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Interactions

What drugs can interfere with the work of the drug Hyoscyamine?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

• Amantadine (Symmetrel);
• Haloperidol (Haldol);
• MAO inhibitors such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);
• Phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Pentazine, Phenergan, Anergan, Antinaus), thioridazine (Compazine, Compro), promethazine (Pentazine, Phenergan, Anergan, Antinaus), thioridazine (Mellarelazine); or
• Antidepressants such as amitriptyline (Elavil, Vanatrip), doxepin (Sinequan), desipramine (Norpramin), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others.

Can certain foods and drinks interfere with the work of Hyoscyamine drugs?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Hyoscyamine?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• Heart disease, congestive heart failure
• Heart rhythm disturbances
• High blood pressure
• Overactive thyroid
• Hiatal hernia with GERD (gastroesophageal reflux disease).

Dose

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of Hyoscyamine for adults?

Usual Adult Dose for Irritable Bowel Syndrome:

Tablet immediate-relase: 0.125-0.25 mg orally or sublingually every 4 hours or as needed. Do not take more than 12 tablets in 24 hours.

Tablet extended-release: 0.375-0.75 mg orally every 12 hours. Do not exceed 4 tablets in 24 hours.

Timecaps: 0.375-0.75 mg orally every 12 hours. Do not exceed 4 capsules in 24 hours

Biphasic Tablets: 0.375-0.75 mg orally every 12 hours. The dose can be adjusted to 0.375 mg every 8 hours, if needed. Do not exceed 4 tablets in 24 hours.

Elixir: 5 to 10 mL (0.125-0.25 mg) every 4 hours or as needed. Don't drink more than 12 teaspoons in 24 hours.

Drops: 1 to 2 mL (0.125-0.25 mg) every 4 hours as needed. Do not use more than 12 mL in 24 hours.

Usual Adult Dose for Anesthesia: 5 mcg / kg given 30-60 minutes before induction of anesthesia or given when preanesthetic or narcotic sedatives are given.

Usual Adult Dose for Endoscopy or Radiology of Premedication:

parenteral: 0.25-0.5 mg (0.5-1 mL) IV 5 to 10 minutes before the diagnostic procedure

Oral Spray: Endoscopic retrograde cholangiopancreatography: 2 sprays (0.25 mg) 20 minutes before the procedure.

What is the dosage of Hyoscyamine for children?

Usual children's dose for urinary incontinence: 2 years to less than 12 years:

Tablet immediate-release:, 0625-0.125 mg sublingually, orally, chewed, every 4 hours or as needed. Do not take more than 6 tablets in 24 hours.

Elixir: 1.25-5 mL (children weighing 10 kg to 50 kg) every 4 hours or as needed. Increase dose gradually 1.25 mL for children weighing 20 kg, and again for children weighing 40 kg. Don't take more than 6 teaspoons in 24 hours.

Drops: 0.25-1 mL (, 0312-, 125 mg) every 4 hours as needed. Do not give more than 6 mL in 24 hours.

Biphasic Tablets: 0.375 mg orally every 12 hours. Do not exceed 2 tablets in 24 hours.

Less than 2 years:

Drops: 4 drops for children 3.4 kg (Do not give more than 24 drops in 24 hours)

5 drops for a child of 5 kg (Do not give more than 30 drops in 24 hours),

6 drops for children 7 kg (Do not give more than 36 drops in 24 hours),

8 drops for a child of 10 kg (Do not give more than 48 drops in 24 hours)

Usual children's dosage for Irritable Bowel Syndrome : Studies (n = 28)

Age 9 years and over: 0.375 mg orally at bedtime, up to 0.75 mg, for up to 6 months.

Usual children's dosage for anesthesia : 5 mcg / kg given 30-60 minutes before induction of anesthesia or given when preanesthetic or narcotic sedatives are given.

In what dosages and preparations is Hyoscyamine available?

Hyoscyamine is available in the following dosages

Elixir, Oral, as sulfate: 0.125 mg / 5 mL (473 mL)

Solution, Injection, such as sulfate: 0.5 mg / mL (1 mL)

Solution, Oral, as sulfate: 0.125mg

Tablet, Oral, as sulfate: 0.125 mg

Dispersible Tablets, Oral, as sulfate: 0.125 mg

Extended Release Tablets, Oral

12 Hour Extended Release Tablets, Oral, as sulfate: 0.375 mg

Sublingual, sublingual, as sulfate: 0.125 mg

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine or forget to take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.