Hydromorphone: functions, dosage, side effects, how to use it

What Medication Hydromorphone?

What is hydromorphone for?

This medication is used to help relieve moderate to severe pain. Hydromorphone is part of a class of drugs known as narcotic (opiate) analgesics. It works in the brain to change how the body feels and responds to pain.

How do I use hydromorphone?

You can take this medication with or without food. If you experience nausea, take this medication with food. Ask your doctor or pharmacist about ways to reduce nausea (such as lying down for 1 to 2 hours with as little head movement as possible).

If you are using the liquid form of this medicine, always measure the dose using a special measuring device. Don't use a home spoon as you may not get the correct dose. Don't be confused if the dose of hydromorphone liquid is in milligrams (mg) with doses in milliliters (ml). Ask your pharmacist or doctor if you are unsure how to check or measure a dose. If your liquid is a suspension, shake the bottle with each dose.

Dosage is based on your medical condition and response to treatment. Do not increase your dose, take the medicine more often, or use it for a longer time than prescribed. This medication works best if it is used when the first signs of pain begin to occur. If you wait until the pain gets too bad, the medicine may not work very well.

If you experience ongoing pain (such as from cancer), your doctor may direct you to take more narcotic drugs. In this case, this drug can be used only as needed when you feel pain. Other non-narcotic pain relievers (such as acetaminophen, ibuprofen) may also be prescribed with this medication. Ask your doctor or pharmacist if you have questions about using hydromorphone safely with other medicines.

This medicine may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as restlessness, watery eyes, runny nose, nausea, sweating, muscle aches) may occur if you suddenly stop using this medicine. To prevent this reaction, your doctor may reduce the dose gradually. Ask your doctor or pharmacist for more details, and report any withdrawal reactions immediately. If this medicine is used for a long time, it may not work well. Talk with your doctor if this drug stops working.

Along with its benefits, this drug may be addictive. This risk may increase if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to reduce your risk of addiction. Tell your doctor if your pain persists or gets worse.

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets. Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Hydromorphone dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for hydromorphone for adults?

Follow the dosage that has been determined by the doctor or according to what is written on the medicine package.

What is the dosage of hydromorphone for children?

The dosage for children has not been determined. Consult your doctor for further details.

In what dosage is hydromorphone available?

Liquid, Oral, as hydrochloride: 1mg / mL (473 mL)
Solution, injection, as hydrochloride: 1mg / mL, 2 mg / mL, 4 mg / mL, 10 mg / mL, 50 mg / 5mL, 500 mg / 5 mL
Reconstituted solution, injection, as hydrochloride: 250 mg
Suppository, Rectal, as hydrochloride: 3 mg
Tablet, Oral, as hydrochloride: 2 mg, 4 mg, 8 mg
ER Tablet 24 Hour Abuse-Deterrant, Oral, as hydrochloride: 8 mg, 12 mg, 16 mg, 32 mg

Hydromorphone side effects

What side effects can be experienced due to hydromorphone?

Call for emergency medical help if you have any of these signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have serious side effects such as:

• shallow breathing or weakness
• the heart beats erratically
• chest tightness, difficulty breathing
• seizures
• confusion, severe weakness, or drowsiness
• feel like passing out

The more serious side effects are:

• blurred vision, double vision
• increased temperature (heat, redness, or tingling feeling)
• nausea, vomiting, constipation, diarrhea, stomach pain
• dizziness, drowsiness
• dry mouth
• sweating
• itchy
• sleep problems (insomnia), or strange dreams.

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Hydromorphone Drug Warnings and Cautions

What should be known before using hydromorphone?

Before consuming hydromorphone,

• tell your doctor and pharmacist if you are allergic to hydromorphone, other drugs, sulfites, or any of the ingredients in hydromorphone tablets, liquid, or extended-release tablets. Ask the pharmacist or see the Medication Guide to see the ingredients.
• tell your doctor and pharmacist what medications, vitamins, nutritional supplements, and herbal products you use or plan to use. Be sure to mention the drugs listed in the IMPORTANT WARNING section and one of the following: buprenorphine (Buprenex, Butrans, at Suboxone, at Zubsolv) butorphanol ipratropium (Atrovent) medication for glaucoma, irritable bowel disease, Parkinson's disease, ulcers, and nalbuphine and pentazocine (Talwin). Also tell your doctor or pharmacist if you are taking any of the following medicines or have stopped taking them in the past two weeks: isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). Your doctor may need to change the dose of your medication or monitor you carefully for side effects.
• tell your doctor if you have any of the conditions listed in the IMPORTANT WARNING section or paralytic ileus (condition in which food doesn't move through the intestines), or a blockage in the stomach or intestines. Your doctor may tell you not to use hydromorphone.
• if you are going to take the extended-release tablet, tell your doctor if you have had surgery that caused a change in the way food moves through your stomach or intestines or if you have a condition that causes narrowing of the esophagus (the tube that carries food from the mouth to the stomach), stomach , or intestines such as cystic fibrosis (a condition that causes the body to produce thick, sticky mucus that can clog the pancreas, lungs, and other parts of the body), peritonitis (inflammation of the lining of the stomach (stomach area), Meckel's diverticulum (a bulge on the lining of the small intestine that is present at birth), chronic intestinal pseudo-obstruction (a condition in which the muscles in the intestines don't move food smoothly through the intestines), or inflammatory bowel disease.Your doctor may tell you not to use the extended-hydromorphone tablet. release.
• tell your doctor if you have or have ever had low blood pressure, Addison's disease (a condition in which the adrenal glands produce less than normal hormones), seizures, any condition that causes difficulty urinating, such as an enlarged prostate (male reproductive gland) or urethral stricture (blockage of the tube that makes it difficult for urine to pass out of the body), or disease of the gallbladder, pancreas, liver, thyroid, or kidneys.
• tell your doctor if you are breastfeeding
• if you are having surgery, including dental surgery, tell your doctor or dentist if you are using hydromorphone
• You should know that hydromorphones can make you sleepy. Do not drive a car or operate machinery until you know how this drug affects you.
• You should know that hydromorphone can cause lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
• You should know that hydromorphone can cause constipation. Talk with your doctor about changing your diet or using other medications to prevent or treat constipation while you are taking hydromorphone.

• Is Gestrinone safe for pregnant or breastfeeding women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Studies show that this drug can change the production or composition of breast milk. If no alternative to this medication is found, you should monitor your baby for side effects and adequate milk intake.

Hydromorphone Drug Interactions

What medicines may interact with hydromorphone?

Interactions with other drugs can affect how the drug works and increase the risk of dangerous side effects. This article does not list all possible drug interactions. Record all medicinal products you use (including prescription, non-prescription and herbal medicines) and show them to your doctor and pharmacist. Do not start, stop, or change the dose of any medication without your doctor's permission. Some of the products that may interact with this medication include: certain pain medications (a mixture of narcotic agonists / antagonists such as pentazocine, nalbuphine, butorphanol), narcotic antagonists (such as naltrexone).

The risk of serious side effects (such as shallow breathing, drowsiness, dizziness) may increase if this medicine is taken with other products that can also affect breathing or cause drowsiness. Therefore, tell your doctor or pharmacist if you are taking other products such as alcohol, allergy medications, or cough-and-cold medicines, anti-seizure medications (such as phenobarbital), sleep or anxiety medications (such as alprazolam, diazepam, zolpidem), muscle relaxants, other narcotic pain relievers (such as codeine, hydrocodone), and psychiatric drugs (such as risperidone, amitriptyline, trazodone). Your medication or medication dose may need to be changed.

This medication may interfere with certain laboratory tests (including amylase / lipase levels), and possibly cause false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Does food or alcohol interact with the Hydromorphone?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

Avoid consuming ethanol if you are on Hydromorphone medication.

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• Sddison's disease (adrenal gland problem)
• alcohol abuse, history
• brain tumor
• breathing or lung problems (eg, chronic obstructive pulmonary disease, cor pulmonale, hypercapnia, hypoxia, sleep apnea)
• CNS depression
• drug dependence, especially narcotic abuse or dependence
• enlarged prostate (BPH, prostate hypertrophy)
• gallbladder disease
• head injury
• hyporthyroidism (underactive thyroid)
• mental illness
• obesity
• bowel problems
• debilitated condition - use with caution. May increase the risk of more serious side effects.
• allergic to sulfites
• opioid intolerant
• paralytic ileus (blockage of the intestine)
• stomach or intestinal problems
• surgery involving the stomach or intestines
• swallowing problems - Exalgo® and Palladone® should not be given to patients with this condition
• breathing problems
• respiratory depression (hypoventilation or slow breathing) - should not be used in patients with this condition
• hypotension (low blood pressure)
• pancreatitis (inflammation of the pancreas)
• seizures - use with caution. It might make things worse.
• Kidney illness
• liver disease - use with caution. The effect can be increased due to slower release of the drug from the body.
• stomach or digestive problems - this medication may be able to mask the diagnosis of this condition.

Hydromorphone overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Overdose symptoms may include:

• breath slows or stops
• sleepy
• coma (loss of consciousness for a period of time)
• muscle weakness
• cool, moist skin
• narrowing or dilation of the pupil (dark circle in the center of the eye)
• heart rate slows or stops
• dizzy
• passed out
• What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose. If you are using an extended-release tablet, skip the missed dose and stick to your regular dosing schedule. Do not take more than one dose of the extended-release tablet in 24 hours.

Hello Health Group does not provide medical advice, diagnosis or treatment.