Demeclocycline: functions, dosage, side effects, how to use

What Drug Demeclocycline?

What is demeclocycline for?

Demeclocycline is a drug used to treat a wide variety of bacterial infections, including those that cause acne. This drug is known as a tetracycline antibiotic. It works by stopping bacterial growth.

This antibiotic treats only bacterial infections. This medicine will not work for viral infections (eg, cold, flu). unnecessary use of antibiotics or misuse of any antibiotics can cause their effectiveness to decrease.

Note This section lists uses for this drug that are not listed on the label of any medicine approved by a health care professional but may have been prescribed by your doctor. Use this medication for the conditions listed in this section if only it has been prescribed by your doctor.

This medication can also be used to treat a certain hormonal imbalance (Syndrome of Inappropriate Antidiuretic Hormone-SIADH) which causes your body to retain water and urine so that it becomes more concentrated than normal. Demeclocycline works by increasing the amount of water in your urine to a more normal level.

Demeclocycline dosage

How do I use demeclocycline?

Take this medication 2 to 4 times daily or as directed by your doctor. Demeclocycline is a drug that works best when taken on an empty stomach at least 1 hour before or 2 hours after a meal.

Take each dose with a glass of water (8 ounces or 240 milliliters) unless your doctor directs you otherwise. Do not lie down for 10 minutes after taking this medicine. For this reason, do not take this medication right before bedtime.

If stomach pain occurs, ask your doctor if you can take this medication with food.

Take this medication 2 to 3 hours before or after taking medications containing magnesium, aluminum, or calcium. Some examples of drugs include quinapril, certain forms of ddl drugs (chewables / dispersed tablets or children's oral solutions), vitamins / minerals, and antacids. Dairy products (eg, milk, yogurt), calcium-fortified juices, sucralfate, subsalicylates, iron, and zinc are also included. The product binds with demeclocycline, preventing full absorption.

Dosage is based on your medical condition and response to treatment. When treating children over 8 years of age, dosage is also based on body weight. For the treatment of infections, children should not take more than 600 milligrams of this medicine per day.

This drug works best when the amount of medicine in your body is at a constant level. Therefore, take this drug regularly.

If you are taking this medication to treat an infection, continue to use it until the prescribed amount is used up, even if symptoms have disappeared after a few days. Stopping treatment too early can result in the infection returning.

Tell your doctor if your condition does not improve or gets worse. If you are taking this medication to treat SIADH, you will notice an increase in the amount of urine within 5 days.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to save demeclocycline?

Democlocyline is this drug is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Demeclocycline side effects

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the demeclocycline dosage for adults?

The usual adult dose for SIADH is:

• Initial dose: 900-1200 mg / day orally in divided doses.
• Maintenance dose: 600-900 mg / day orally in divided doses

Usual adult dose for infection

• 600 mg per day in 2 or 4 divided doses

Usual adult dose for infection

• 900 mg per day in 3 divided doses for 6 days

What is the dose of demeclocycline for children?

This medicine is not recommended for children <12 years.

In what dosage is demeclocycline available?

Demeclocycline is a drug that is available in tablets, orally as hydrochloride 150 mg, 300 mg.

Demeclocycline Drug Warnings and Cautions

What side effects can be experienced due to demeclocycline?

Common side effects of Declomycin include sores or swelling in your rectal or genital area, nausea, vomiting, diarrhea, loss of appetite, white patches or sores in the mouth, swollen tongue, difficulty swallowing, and vaginal itching or discharge.

Get emergency medical help if you have signs of an allergic reaction such as: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Stop using demeclocycline and call your doctor if you have serious side effects such as:

• fever, chills, body aches, flu symptoms
• easy bruising, unusual bleeding (on the nose, mouth, vagina, or rectum), purple or red spots under your skin;
• pale skin, dark urine, jaundice (yellowing of the skin or eyes)
• confusion, mood changes, weakness, thirst or increased urination
• swelling, weight gain, less or no urinating than usual
• chest pain, wheezing, dry cough, rapid breathing, feeling short of breath
• tingling, numbness, pain, severe muscle weakness
• headache, ringing in the ears, dizziness, nausea, visual disturbances, pain behind your eyes
• sore throat and severe headache, peeling skin, and red skin rash
• severe pain in the upper abdomen and spreading to the back, nausea and vomiting, fast heart rate.

Less serious side effects may include:

• sores or swelling in the rectum or genital area
• mild nausea, vomiting, diarrhea, loss of appetite
• white patches or sores inside your mouth or lips
• swollen tongue, difficulty swallowing or
• vaginal itching or discharge

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Demeclocycline Drug Interactions

What should be known before using demeclocycline?

Demeclocycline is a drug that must be used under a doctor's supervision. Before using demeclocycline, tell your doctor and pharmacist if you are allergic to demeclocycline, tetracycline, minocycline, doxycycline, or any other medication.

Tell your doctor and pharmacist about prescription and nonprescription drugs, vitamins, nutritional supplements, and herbal products that you are using or will be using. Be sure to mention the following: antacids, anticoagulants ("blood thinners") such as warfarin (Coumadin), and penicillins. Demeclocycline reduces the effectiveness of some oral contraceptive medicines. Other forms of birth control medication should be used while using this medication.

Be aware that antacids, calcium supplements, iron products, and laxatives that contain magnesium interfere with demeclocycline, making them less effective. Take demeclocycline 1 hour before or 2 hours after antacids (including sodium bicarbonate), calcium supplements, and laxatives containing magnesium. Take demeclocycline 2 hours before or 3 hours after taking iron and vitamin products that contain iron.

Tell your doctor if you have or have ever had diabetes or kidney or liver disease. Also tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. If you become pregnant while using demeclocycline, contact your doctor immediately. Demeclocycline can be harmful to the fetus.

If you are having surgery, including dental surgery, tell your doctor or dentist about using demeclocycline.

Plan to avoid unnecessary or prolonged sun exposure and wear protective clothing, sunglasses, and sunscreen. Demeclocycline can make your skin sensitive to sunlight.

You should know that when demeclocycline is used during pregnancy or in infants or children up to 8 years of age, it can cause permanent staining of teeth. Demeclocycline should not be used in children under 8 years of age unless your doctor determines that the patient really needs it.

Is demeclocycline safe for pregnant and breastfeeding women?

Demeclocycline is a drug that has been put into pregnancy category D by the Food and Drug Administration (BPOM) in America, aka "there is evidence of risk."

Animal studies have shown evidence of fetal toxicity and teratogenic effects associated with tetracycline use. Demeclocycline flows through the placenta at an average concentration of 65% of the maternal blood level. There are no research data on human pregnancy. However, congenital defects associated with tetracycline use have been reported, including a toxic effect on bone formation.

When used during tooth development (other than during pregnancy) tetracyclines can cause permanent gray-brown discoloration of teeth and enamel hypoplasia.

Demeclocycline should be given with extreme caution during pregnancy. Demeclocycline is only recommended for use during pregnancy if alternatives are not available and if the benefits outweigh the risks. Pregnant patients or patients who have recently become pregnant while using demeclocycline should be informed about the potential harm to the fetus.

There are no data regarding the excretion of demeclocycline into human milk. However, tetracyclines are excreted into human milk in small amounts. The tetracycline concentration in milk averages 0.6 mcg / mL when the blood level is around 1.2 mcg / mL.

There is a theoretical risk of tooth staining and inhibition of bone growth, although they are rare. In one study, tetracycline levels were undetectable in breastfeeding infants. Tetracyclines, and other related drugs, are considered suitable for breastfeeding mothers by the American Academy of Pediatrics.

Because of the potential for serious side effects in a nursing infant, the manufacturer recommends that a decision should be made to stop breastfeeding or stop using the drug considering the importance of the drug's benefit to the mother.

Demeclocycline overdose

What medicines might interact with demeclocycline?

Some DRUGS MAY INTERACT with demeclocycline. Tell your doctor if you are taking other drugs, especially any of the following:

Acitretin, anticoagulants (eg, warfarin), digoxin, isotretinoin, methotrexate, or methoxiflurane because the risk of side effects and toxic effects can be increased with demeclocycline

• Penicillin (for example, amoxicillin) or hormonal birth control (for example, birth control pills) because the effectiveness of birth control pills may decrease due to demeclocycline

This list may not be a complete list of all possible interactions. Ask your doctor if demeclocycline can interact with other medicines you use. Check with your doctor before you start, stop, or change the dose of any medication.

Can food or alcohol interact with demeclocycline?

Demeclocycline is a drug that can react if you eat or drink beverages such as alcohol. Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with demeclocycline?

The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems.

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.