Daptomycin: functions, dosage, side effects, how to use

What is the drug Daptomycin?

What is daptomycin for?

Daptomycin is an antibiotic used to treat serious bacterial infections. This drug works by stopping the growth of bacteria.

Daptomycin is a lipopeptide class antibiotic. This medicine should not be used to treat pneumonia. If it is used to treat pneumonia, you may experience severe side effects (especially heart problems and breathing problems). Consult your doctor for more info.

How is daptomycin used?

This medication is given by injection into a vein as directed by your doctor, usually once daily. If you have severe kidney disease or are on kidney dialysis you should only use this medicine on a different day (that is, every 48 hours). Usually this medication is used for two weeks or as directed by your doctor.

If you are giving this medication to yourself at home, learn all the preparations and directions for use from your doctor. Before using the drug, check the condition of this product visually for the presence of particles or discoloration. If this occurs, do not use this drug. Learn how to store and dispose of medical supplies safely.

Antibiotics work best when the amount of medicine in your body is at a constant level. Therefore, use this drug regularly.

Continue to use the medication until the prescribed amount is finished even if symptoms disappear after a few days. Stopping treatment too early allows bacteria to continue to grow and can result in a recurrence of infection.

Tell your doctor if your condition does not improve within one week (such as having a new fever or getting worse).

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How is daptomycin stored?

Daptomycin is a drug that should be stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Daptomycin dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of daptomycin for adults?

• To treat skin infections and skin tissue infections, the dose of daptomycin is 4 mg / kg intravenously in 30 minutes every 24 hours for 7 to 14 days.
• To treat Staphylococcus aureus bacteremia, the daptomycin dose is 6 mg / kg by infusion in 30 minutes every 24 hours for 2 to 6 weeks.

What is the dose of daptomycin for children?

There is no prescribed dosage for this drug for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use. Consult your doctor or pharmacist for more information.

In what dosage is daptomycin available?

The availability of the drug daptomycin is a liquid dissolved 500 mg.

Daptomycin side effects

What side effects can be experienced due to daptomycin?

Mild side effects that may occur from the drug daptomycin are:

• Nausea
• Gag
• Diarrhea
• Constipation
• Headache
• Body aches
• Restless
• Sleep problems (insomnia)
• Mild itching or skin rash
• Excessive sweating
• Reddish rash, discomfort, or irritation at the injection site

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Daptomycin Drug Warnings and Cautions

What should be known before using daptomycin?

Some things you should know before taking daptomycin are:

• Before using daptomycin, tell your doctor and pharmacist if you are allergic to daptomycin or any other medications.
• Tell your doctor and pharmacist about prescription and nonprescription drugs, vitamins, nutritional supplements, and herbal products that you use or plan to use. Be sure to name one of the following drugs: cholesterol-lowering drugs (statins) such as atorvastatin (Lipitor, in Caduet), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor, di Advicor), pravastatin (Pravachol), rosuvastatin (Crestor), simvastatin (Zocor, in Vytorin). Your doctor may need to change the dose of your medication or watch you carefully for side effects.
• Tell your doctor if you have or have ever had kidney disease.
• Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using daptomycin injections, call your doctor.

Is daptomycin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or nursing women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category B according to the US Food and Drug Administration (FDA) United States, or the equivalent of the POM in Indonesia.

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = May be risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

There are not adequate studies in women who pose a risk to the baby when using this medicine during breastfeeding. Weigh the benefits against the risks before using this medicine while breastfeeding.

Daptomycin Drug Interactions

What medicines might interact with daptomycin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Although certain drugs should not be used together, in other cases two different drugs can be used together even if interactions are possible. In this case, your doctor may want to change the dose or take other precautions that may be needed. When you are using this medicine it is important that your doctor knows if you are currently taking any of the medicines that are listed below. The following interactions are selected on the basis of their potential significance and are not necessarily all inclusive.

Using this medication with any of the following medicines is not usually recommended, but may be necessary in some cases. If the two drugs are prescribed together, your doctor may change the dose or change how often you use one or both drugs.

• Atorvastatin
• Fluvastatin
• Lovastatin
• Pravastatin
• Rosuvastatin
• Simvastatin

Can food or alcohol interact with daptomycin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with daptomycin?

The presence of other health problems in your body may affect the use of this drug. Some of the conditions that may interact with the drug daptomycin are:

• Diarrhea
• Muscle problems
• Nerve problems (for example, neuropathy)
• Kidney illness
• staphylococcus infection, is ongoing or has gone away

Daptomycin overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.