Table of contents:
- Functions & Usage
- What is Bumetanide used for?
- How do you use Bumetanide?
- How to store Bumetanide?
- Dose
- What is the dosage for Bumetanide for adults?
- Adults with swelling of the abdomen (ascites)
- Adults with swelling of the legs (edema)
- Adults with fluid build-up in the lungs (pulmonary edema)
- Adults with liver disorders
- Dosage adjustments
- What is the dosage of Bumetanide for children?
- In what dosages and preparations is Bumetanide available?
- Side effects
- What are the possible side effects of Bumetanide?
- Precautions & Warnings
- What should be considered before using the drug Bumetanide?
- Is Bumetanide safe for pregnant and lactating women?
- Drug Interactions
- What drugs can interfere with the action of the drug Bumetanide?
- Can certain foods and drinks interfere with the work of the Bumetanide drug?
- What health conditions can interfere with the performance of the drug Bumetanide?
- Overdose
- What should I do in an emergency or overdose?
- What should I do if I miss a dose?
Functions & Usage
What is Bumetanide used for?
Bumetanide is a drug to reduce excess fluid buildup in the body (edema) caused by various conditions, such as heart failure, liver disease, and kidney disease. This medication can reduce symptoms such as shortness of breath and swelling in the arms, legs, and stomach. Bumetanide is a "water pill" (diuretic) that causes you to produce more urine. Urinating helps your body get rid of excess water and salt.
OTHER USES: This section contains uses of this medication that are not listed on the label for drugs approved by your health care professional, but may be prescribed by your healthcare professional. Use this medication for the conditions listed in this section if only it has been prescribed by your healthcare professional.
Another function of the drug bumetanide is to treat high blood pressure, especially in people who have heart failure, too much fluid in the lungs, or kidney disease. Lowering your high blood pressure can help prevent strokes, heart attacks, and kidney problems.
How do you use Bumetanide?
Take this medication as directed by your doctor, usually once or twice a day. The recommendation if you are taking bumetanide is not to take this medicine 4 hours before bed to prevent having to get up in the middle of the night to urinate.
Dosage is based on your medical condition and response to treatment. Older adults usually start with lower doses to reduce the risk of side effects. Do not increase your dose or use this medication more often than directed.
Use this remedy regularly to get its benefits. To help you remember, use it at the same times each day as directed. It is important to continue taking this medication even if you are already feeling well. Most people with high blood pressure don't feel sick.
Tell your doctor if your condition does not improve or gets worse. If you are taking this medicine to control high blood pressure, tell your doctor if your blood pressure reading remains high or gets elevated.
Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.
How to store Bumetanide?
This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.
Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.
Dose
The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.
What is the dosage for Bumetanide for adults?
For adults, the following bumetanide dosages are:
Adults with swelling of the abdomen (ascites)
Oral: 0.5-2 mg once a day. IV or IM: 0.5-1 mg once. Continuous IV infusion: 1 mg / hour to 12 mg / day.
Adults with swelling of the legs (edema)
Oral: 0.5-2 mg once a day. IV or IM: 0.5-1 mg once. IV continuous IV infusion: 1 mg / hour to 12 mg / day.
Adults with fluid build-up in the lungs (pulmonary edema)
Oral: 0.5-2 mg once a day. IV or IM: 0.5-1 mg once. IV continuous IV infusion: 1 mg / hour to 12 mg / day.
Adults with liver disorders
Patients with cirrhosis and ascites should be given smaller doses of bumetanide because of the risk of altered electrolyte balance which can lead to hepatic encephalopathy.
Dosage adjustments
The oral dose can be titrated every 4 hours. The IV dose can be titrated every 2 to 3 hours. Patients with edema often benefit from use on alternate days or every 3 to 4 days. Patients with liver disease and renal dysfunction should have carefully adjusted the dosage.
What is the dosage of Bumetanide for children?
Consult your doctor or pharmacist for more information.
In what dosages and preparations is Bumetanide available?
- Solution, Injection: 0.25 mg / mL (2 mL, 4 mL, 10 mL)
- Tablet, Oral: 0.5 mg, 1 mg, 2 mg (Burimex® Dosage form, Canada)
Side effects
What are the possible side effects of Bumetanide?
A common side effect when you take bumetanide is dizziness because your body adjusts to the drug. Tell your doctor if you experience:
- Muscle cramp
- Weakness
- Fatigue
- Confusion
- Dizzy
- Fainting
- Sleepy
- Dry / thirsty mouth
- Nausea
- Gag
- Fast / irregular heartbeat
- an unusual drop in the amount of urine may be a sign of severe dehydration.
Get emergency medical help if you have signs of an allergic reaction such as: hives; hard to breath; swelling of the face, lips, tongue, or throat.
Stop using bumetanide and call your doctor if you experience serious side effects. Some of the serious side effects that can occur when using bumetanide are:
- Feel like passing out
- Low potassium (confusion, uneven heart rate, extreme thirst, increased urination, discomfort in the legs, muscle weakness or a feeling of weakness)
- Headache, difficulty concentrating, memory problems, weakness, loss of appetite, feeling shaky, hallucinations, seizures, shallow breathing or breathing that stops
- Easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin
- Fever, sore throat, and severe headache, peeling skin, and red skin rash
- Hearing problems
Less serious side effects of using bumeta:
- Mild muscle pain
- Dizzy
- Headache
- Stomach pain, mild nausea
- Mild itching or skin rash
Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.
Precautions & Warnings
What should be considered before using the drug Bumetanide?
Things you need to do before using bumetanide are:
- Tell your doctor and pharmacist if you are allergic to bumetanide, sulfa drugs, or any other medications
- Tell your doctor and pharmacist about prescription drugs and nonprescription drugs you are using, especially other drugs for high blood pressure, corticosteroids (eg prednisone), digoxin (Lanoxin), indomethacin (Indocin), lithium (Eskalith, Lithobid), probenecid (Benemid) , and vitamins.
- Tell your doctor if you have or have ever had diabetes, gout, or kidney or liver problems
- Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Do not breastfeed while using this medicine. If you become pregnant while using bumetanide, call your doctor.
- If you are having surgery, including dental surgery, tell your doctor or dentist about using bumetanide.
Is Bumetanide safe for pregnant and lactating women?
There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).
The following references the pregnancy risk categories according to the FDA:
- A = Not at risk
- B = not at risk in several studies,
- C = May be risky
- D = There is positive evidence of risk,
- X = Contraindicated
- N = Unknown
There are not sufficient studies in women to determine the risk to the baby when using this medicine during breastfeeding. Consider the benefits and risks before using this medication while breastfeeding.
Drug Interactions
What drugs can interfere with the action of the drug Bumetanide?
Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval
Although certain drugs should not be used together, in other cases two different drugs can be used together even if interactions are possible. In this case, your doctor may change the dose, or take other precautions that may be needed. When you are using this medicine it is very important that your healthcare provider knows if you are currently taking any of the medicines that are listed below. The following interactions are selected on the basis of their potential significance and are not necessarily all inclusive.
Using this medication with any of the following medicines is not usually recommended, but may be necessary in some cases. If the two drugs are prescribed together, your doctor may change the dose or adjust how often you use one or both drugs.
- Arsenic Trioxide
- Bepridil
- Digitoxin
- Dofetilide
- Droperidol
- Ketanserin
- Levomethadyl
- Lithium
- Metolazone
- Sotalol
Using this medication with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor may change the dose or adjust how often you use one or both drugs.
- Aceclofenac
- Acemetacin
- Alacepril
- Amtolmetin Guacil
- Aspirin
- Benazepril
- Bromfenac
- Bufexamac
- Captopril
- Celecoxib
- Choline Salicylate
- Cilazapril
- Clonixin
- Delapril
- Dexibuprofen
- Dexketoprofen
- Dibekacin
- Diclofenac
- Dislunisal
- Dipyrone
- Enalaprilat
- Enalapril Maleate
- Etodolac
- Etofenamate
- Etoricoxib
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Floctafenine
- Flufenamic Acid
- Flurbiprofen
- Fosinopril
- Germanium
- Ginseng
- Gossypol
- Ibuprofen
- Ibuprofen Lysine
- Imidapril
- Indomethacin
- Kanamycin
- Ketoprofen
- Ketorolac
- Licorice
- Lisinopril
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Meclofenamate
- Mefenamic Acid
- Meloxicam
- Moexipril
- Morniflumate
- Nabumetone
- Naproxen
- Neomycin
- Nepafenac
- Niflumic Acid
- Nimesulide
- Oxaprozin
- Oxyphenbutazone
- Parecoxib
- Pentopril
- Perindopril
- Phenylbutazone
- Piketoprofen
- Piroxicam
- Pranoprofen
- Proglumetacin
- Propyphenazone
- Proquazone
- Quinapril
- Ramipril
- Rofecoxib
- Salicylic Acid
- Salsalate
- Sodium Salicylate
- Spirapril
- Streptomycin
- Sulindac
- Temocapril
- Tenoxicam
- Tiaprofenic Acid
- Tolfenamic Acid
- Tolmetin
- Trandolapril
- Valdecoxib
- Zofenopril
Can certain foods and drinks interfere with the work of the Bumetanide drug?
Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.
What health conditions can interfere with the performance of the drug Bumetanide?
The presence of other health problems in your body may affect the use of this medicine. Tell your doctor if you have other health problems, such as:
- Anuria (unable to form urine)
- Liver disease, severe (for example, hepatic coma) - should not be used in patients with this condition.
- Dehydration
- Gout
- Hyperuricemia (high uric acid in the blood)
- Hypocalcemia (low calcium in the blood)
- Hypokalemia (low potassium in the blood)
- Hypomagnesemia (low magnesium in the blood)
- Hypovolemia (low blood volume)
- Thrombocytopenia (low platelets in the blood) - Use with caution. This medicine can make the condition worse.
- Diabetes - this medication can increase the amount of sugar in the blood.
Overdose
What should I do in an emergency or overdose?
In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.
What should I do if I miss a dose?
If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
