Tolinase: function, dosage, side effects, how to use

Uses

What is Tolinase for?

Tolinase is a drug intended for type two diabetes patients who are not yet dependent on insulin injection. Tolazamide, which is the active ingredient in Tolinase, helps the body of type two diabetes patients to better control their blood sugar levels. Tolinase is prescribed when diet and exercise programs, which are the mainstays of therapy in type two diabetes patients, do not show a satisfactory decrease in blood sugar levels.

Tolinase is an oral drug whose use can be combined with drugs antidiabetics agent others if needed. Tolinase is not intended for patients with type one diabetes. Tolazamide contained in Tolinase is a sulfonylurea class drug that works by stimulating your pancreas to release your body's natural insulin.

What are the rules for using Tolinase?

This medication is an oral medication that is usually taken once a day before breakfast or the first big meal of the day. Follow the instructions given by your doctor or pharmacist regarding taking Tolinase. Do not add or subtract them without consulting your doctor.

The initial dose given by your doctor may increase over time by taking into account your body's response and the condition of your sugar levels. Routine blood sugar level checks while taking this medicine are recommended to find out the extent to which Tolinase is working in your body. If you are taking other diabetes medications, such as chlorpropamide, follow your doctor's instructions carefully to avoid the risk of hypoglycemia.

How are the Tolinase storage rules?

Store this drug at room temperature between 20-25 degrees Celsius in a closed container. Keep away from damp places and direct sunlight. Do not freeze this medication or store it in the bathroom.

Dose

What is the Tolinase dosage for adults?

Adult patients with type 2 diabetes:

• 100-250 mg at baseline, once daily, in the morning.
• Increase the dosage by 100-250 mg daily if needed
• Maintenance dose: 250-500 mg daily
• Maximum dose per day: 1,000 mg per day

For doses up to 500 mg, this is done in the morning before the first meal of the day. If the dose given exceeds 500 mg per day, it is possible to break it down into two times a day.

Elderly patients: 100 mg daily in the morning

In what dosage and preparation is Tolinase available?

Tablet, oral: 100 mg, 250 mg, 500 mg.

Side effects

What side effects may occur due to Tolinase consumption?

Tolinase is a drug that affects blood sugar levels. Hypoglycemia can occur, recognize the signs to take anticipatory steps. Stomach cramps, flatulence, heartburn, loss of appetite, constipation, diarrhea, nausea, vomiting, and weight gain may occur due to consumption of this drug. Tell your doctor right away if these symptoms persist or get worse.

Tell your doctor right away if you have any serious side effects, including skin discoloration (darkening or thickening), unusual fatigue, easy bruising or bleeding, mood swings, sudden weight gain, swelling of the hands and feet, muscle pain. , yellowing of the eyes and skin, severe pain in the stomach, dark urine, to seizures. Hemolytic anemia and aplastic anemia have also been reported due to the use of sulfonylureas.

Although it causes some serious side effects, the use of this drug is generally considered to be safe. Clinical studies conducted on 1,784 diabetics (people with diabetes) who took Tolinase, only 2.1 percent who then stopped the therapy due to side effects caused. Talk to your doctor about your body condition and other possible side effects that you are concerned about to minimize the risk.

Warnings and Precautions

What should I know before taking Tolinase?

• Tell your doctor if you have an allergy to Tolazamide (the main active ingredient in Tolinase) and other drugs, including non-prescription drugs and herbal medicines. This medicine may contain other ingredients that have the potential to cause allergies.
• Tell your doctor about any drug therapy you are currently taking to take Tolinase. Also inform your medical history, such as diseases that you have suffered (kidney disease, thyroid problems, liver problems).
• Limit alcohol use while taking this drug as this will increase the risk of a drastic drop in blood sugar. Although rare, the Tolazamide interactions in this drug can cause nausea, vomiting, dizziness, or pain in the stomach.
• This medication may also make you more sensitive to the sun. Limit yourself from direct sun exposure by using sun cream or clothing that protects you. Contact your doctor if you find signs of skin burning or sores / redness.

Is Tolinase safe for pregnant women?

The Food and Drug Administration, United States classifies this drug into category C drugs (may be risky). Animal trials suggest a risk, but no studies have been conducted in humans. Consult your doctor if you have any plans or are pregnant and breastfeeding.

Drug Interactions

What drugs may interact with toolinase?

The use of certain drugs at the same time is not recommended because they can cause drug interactions. Drug interactions can increase the risk of side effects or decrease the performance of one drug. Even so, sometimes doctors prescribe two drugs that interact simultaneously if needed. Pay close attention to the instructions given by your doctor regarding taking drugs that interact with each other.

Concomitant use of Tolinase with other diabetes medications can increase the chances of developing hypoglycemia. Follow your doctor's instructions if your doctor does prescribe these two drugs at the same time.

Talk to your doctor about all the products you are currently using or have used in the past. This is useful for knowing the possibility of drugs that interact with Tolinase.