Streptozocin: functions, dosage, side effects, how to use

Functions & Usage

What is the drug Streptozocin used for?

Streptozocin is a drug for cancer therapy that interferes with the growth and spread of cancer cells in the body.

Streptozocin is used to treat pancreatic cancer.

Streptozocin may also be used for purposes not listed in this medication guide.

How do you use the drug Streptozocin?

Streptozocin is injected into a vein through an IV. A health care provider will provide this injection.

Streptozocin can lower blood cells that help the body fight infection and help blood to clot. Your blood will need to be tested frequently. Treatment of your cancer may be delayed based on the results of this test.

How to store Streptozocin?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Precautions & Warnings

What should be considered before using the drug Streptozocin?

Before using certain drugs, consider the risks and benefits first. This is a decision you and your doctor will have to make. For this drug, pay attention to the following:

Allergy

Tell your doctor if you have any unusual or allergic reactions to this or any other medicine. Also tell your doctor if you have any other types of allergies such as to food, coloring, preservatives, or animal allergies. For over-the-counter products, read the labels on the packaging carefully.

Children

There is no specific information comparing use of Streptozocin in children with use in other age groups.

Elderly

Many drugs have not been studied specifically in older people. Therefore, it may not be known whether the drugs work in the same way as they do in younger adults or if they cause different side effects or problems in the elderly. There is no specific information comparing use of Streptozocin in the elderly with use in other age groups.

Is the drug Streptozocin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or nursing women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category D. (A = No risk, B = No risk in some studies, C = Possible risk, D = There is positive evidence of risk, X = Contraindicated, N = unknown)

Side effects

What are the possible Streptozocin side effects?

If you experience serious side effects of Streptozocin such as the following, then contact your doctor immediately or seek medical help immediately:

• Allergic reaction (difficulty breathing, narrowed throat, swelling of the lips, tongue, or face, or hives)
• Kidney damage (little or no urine production, blood in the urine)
• Liver problems (change in blood test results, stomach pain, yellowing of the skin or eyes, decreased appetite, nausea)
• Decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black or bloody stools, or fever, chills, or signs of infection)
• Severe nausea, vomiting, loss of appetite, or diarrhea
• In some cases, secondary cancer was reported during and after treatment with Streptozocin. Talk to your doctor about the risks and benefits of this drug.

Other, less serious side effects may be more likely. Continue to use Streptozocin and consult your doctor if you experience:

• Mild nausea, vomiting, loss of appetite, or diarrhea
• Sleepy
• Confusion
• Depression
• The area affected by the injection may experience swelling, redness, burning, or tenderness.

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Interactions

What drugs can interfere with the drug Streptozocin?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Using this medication with any of the following medicines is not recommended. Your doctor may not prescribe this medicine to you or will replace some of the drugs you are already taking.

• Rotavirus Vaccine, Live

Using this medication with any of the following medicines is not usually recommended, but may be necessary in some cases. If the two drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

• Adenovirus Vaccine Type 4, Live
• Adenovirus Vaccine Type 7, Live
• Bacillus of Calmette and Guerin Vaccine, Live
• Influenza Virus Vaccine, Live
• Measles Virus Vaccine, Live
• Mumps Virus Vaccine, Live
• Rubella Virus Vaccine, Live
• Vaccine Smallpox
• Typhoid Vaccine
• Varicella Virus Vaccine
• Yellow Fever Vaccine

Can certain foods and drinks interfere with the action of the drug Streptozocin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Streptozocin?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• Smallpox (including recent exposure)
• Shingles (shingles) - Risk of severe disease affecting other parts of the body
• Type 2 diabetes mellitus - May get worse
• Infection - Streptozocin can decrease your body's ability to fight infection
• Kidney illness
• Liver disease - The effects of Streptozocin may be increased due to the slow process of breaking down the drug from the body

Dose

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of the drug Streptozocin for adults?

500 mg / m2 IV by rapid injection or instantaneous / prolonged infusion once daily for 5 consecutive days every 6 weeks until maximum benefit or treatment limit toxicity occurs. A dose escalation is not recommended with this regimen.

Alternatively, 1000 mg / m2 IV by rapid injection or short / prolonged infusion may be given at weekly intervals for the first 2 weeks. This can be followed by a dosage

This may be followed by dose escalation not exceeding a single dose of 1,500 mg / m2 IV in patients who have not achieved a therapeutic response and have not experienced significant toxicity with the previous program.

What is the dosage of the drug Streptozocin for children?

Safety and effectiveness have not been determined in pediatric patients (less than 18 years).

In what dosages and preparations is Streptozocin available?

Powder 1 g

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (118/119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine or forget to take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.