Ibuprofen: functions, dosage, side effects, how to use it

What Drug Ibuprofen?

What is ibuprofen for?

Ibuprofen is a drug with a function to relieve pain, due to various conditions such as:

• headache
• tooth ache
• back pain
• menstrual pain
• muscle ache
• uric acid
• arthritis
• other inflammation of the body

This medication is also used to reduce fever and relieve minor aches and pains due to colds or flu. Ibuprofen is a class nonsteroidal anti-inflammatory drugs (NSAID). These drugs work by blocking the production of natural substances in the body that cause inflammation.

When you feel pain, pain, or inflammation, your body naturally produces chemicals called prostaglandins. Ibuprofen has the ability to stop the production of prostaglandins by the body, so that pain is relieved.

If you are treating a chronic condition such as arthritis, talk to your doctor about non-drug therapy and / or using other medications to treat your pain.

How do you take ibuprofen?

Read the drug manual and the Patient Information Leaflet provided by the pharmacy if you have one, before you get this medication and each time you buy again. If you have questions, ask your doctor or pharmacist.

Take ibuprofen, usually every 4-6 hours, with a glass of water (240mL) unless your doctor recommends otherwise. Do not lie down for at least 10 minutes after taking the medicine. If you experience stomach upset while using this medicine, take it with food, milk, or antacids.

The dosage is always given based on your health condition and how you respond to therapy. To reduce the risk of stomach bleeding and other side effects, use the lowest possible dose of the effective drug.

Do not increase your dose or use it more frequently than your doctor or packaging label recommends. For certain conditions, such as arthritis, it can take up to 2 weeks of regular use for the benefits to be felt.

Remember that pain medications work best if they are taken when the pain occurs. Don't wait for the pain to become intense. Medicines may not work well.

If your condition does not improve or gets worse, consult a doctor immediately. If you are taking non-prescription ibuprofen (over-the-counter drugs) to treat fever or pain in yourself / your child, consult a doctor if the fever does not go away after 3 days. Immediately to the doctor too if the pain you feel lasts more than 10 days.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store this drug?

Ibuprofen is best stored at room temperature, away from direct light and damp places. Do not store this medication in the bathroom or freeze it. Other brands of this drug may have different storage rules.

Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Ibuprofen dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for ibuprofen for adults?

The following are the recommended dosages of ibuprofen for adults:

Menstrual pain

To treat menstrual pain, the required dose is 200-400 mg orally every 4-6 hours as needed.

Osteoarthritis patients

The recommended dose for osteoarthritis patients is 400-800 mg orally every 6-8 hours as needed.

Sufferers rheumatoid arthritis

People with rheumatoid arthritis are encouraged to take 400-800 mg orally every 6-8 hours as needed.

Mild to moderate aches or pains

• Oral: 200-400 mg orally every 4-6 hours as needed.
• By infusion: 400-800 mg intravenously for 30 minutes every 6 hours as needed.

Fever

• Oral: 200-400 mg orally every 4-6 hours as needed.
• By infusion: the initial dose is 400 mg by infusion for 30 minutes. A follow-up dose of 400 mg every 4-6 hours, or 100-200 mg every 4 hours as needed.

What is the dosage for ibuprofen for children?

The following are the recommended dosages of ibuprofen for children:

Fever in children

6 months to 12 years of age: 10 mg / kg / dose orally every 6-8 hours as needed.

Pain in children

6 months to 12 years of age: 4-10 mg / kg orally every 6-8 hours as needed. The maximum recommended daily dose is 40 mg / kg.

Rheumatoid arthritis in children

Age 6 months to 12 years

Normal: 30-40 mg / kg / day in 3-4 divided doses. Starting from the lowest dose and titration. Patients with milder disease can be treated at a dose of 20 mg / kg / day.

Cystic fibrosis in children

• Dosage of ibuprofen for children with cystic fibrosis. Oral: chronic / chronic (more than 4 years) 2 times daily adjusted to maintain serum concentrations of 50-100 mcg / mL associated with delayed disease progression in pediatric patients with mild pulmonary disease.
• The dosage of ibuprofen for children with Patent Ductus Arteriosus. Ibuprofen lysine: gestational age ≤32 weeks, birth weight: 500-1500 g, initial dose: 10 mg / kg, followed by 2 doses of 5 mg / kg after 24 and 48 hours

In what dosage is this drug available?

Suspension, Oral: 100 mg / 5 mL.

Ibuprofen side effects

What side effects can I experience due to ibuprofen?

Most medicines can cause side effects in certain people after consumption. This also applies to the drug ibuprofen.

Common and mild side effects of ibuprofen are:

• stomach pain, ulcer, diarrhea, constipation
• bloating
• dizziness, headache, nervousness
• itching or skin rash
• ringing in the ears

In addition to the side effects above, it is possible that Antalgin can trigger an allergic drug reaction. Seek medical help right away if you experience an allergic reaction:

• itchy rash
• severe skin rash
• difficulty breathing
• swelling of the face, lips, tongue, or throat

Stop using the drug and contact your doctor immediately if you experience serious side effects from ibuprofen, such as:

• chest pain, weakness, tightness, slurred speech, vision problems or loss of balance
• The stool is black, bloody, or has a liquid and sticky texture, coughs up blood or vomits like coffee
• swelling or rapid weight gain
• difficulty or infrequent urination
• nausea, upper abdominal pain, itching, no appetite, dark urine, putty bowel movements, jaundice (yellowing of the skin or eyes)
• fever, sore throat, and headache with blisters, peeling, and red skin rash
• bruising, severe tingling, numbness, pain, muscle weakness; or
• severe headache, neck stiffness, chills, increased sensitivity to light, and / or seizures (convulsions)

Not everyone experiences the following side effects. There may be some side effects not listed above.

If you have concerns about certain side effects, consult your doctor or pharmacist.

Warnings and Cautions

What should be known before using ibuprofen?

Before using certain drugs, consider the risks and benefits first. This is a decision you and your doctor will have to make. For this drug, pay attention to the following:

1. Allergies

Tell your doctor if you have any unusual or allergic reactions to this or any other medicine. Also tell your doctor if you have any other types of allergies such as to food, coloring, preservatives, or animal allergies. For over-the-counter products, read the labels on the packaging carefully.

2. Elderly

Sufficient research to date has shown no specific problems in elderly patients that will limit the effectiveness of ibuprofen in the elderly. However, elderly patients are more likely to suffer from muscle-related problems, which elderly patients taking ibuprofen may need to pay attention to.

Is this drug safe for pregnant and lactating women?

There is no adequate research on whether ibuprofen is safe for pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

This medicine falls into a category C (possibly risky) pregnancy risk according to US Food and Drug Administration (FDA). The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = May be risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

Ibuprofen Drug Interactions

What medicines may interact with ibuprofen?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Tell your doctor all medicines you use, in particular:

• aspirin or other NSAIDs (naproxen, celecoxib, diclofenac, meloxicam)
• heart and blood pressure medications (benazepril, enalapril, lisinopril, quinapril)
• lithium (Eskalith, Lithobid)
• diuretics such as furosemide (Lasix)
• methotrexate (Rheumatrex, Trexall)
• steroid (prednisone)
• blood thinners such as warfarin (Coumadin, Jantoven)

Can food or alcohol interact with this drug?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur.

Smoking or consuming alcohol with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with ibuprofen?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems.

Some of the medical conditions of a person taking ibuprofen must be monitored, even if the person has certain diseases, he should not take ibuprofen.

You should not take ibuprofen if you have:

• severe heart failure
• acute liver disease
• have a history of inflammation or sores in the digestive tract
• have a history of allergies to NSAID-type drugs

You should be under the supervision of a doctor when taking ibuprofen if you experience:

• asthma
• have kidney or liver disorders
• lupus
• Crohn's disease
• hypertension
• stroke
• have heart problems, such as having had a heart attack or having angina pectoris
• have experienced bleeding in the stomach

Ibuprofen overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Overdose symptoms include:

• dizzy
• lips, mouth and nose are blue
• slow breathing or brief stops
• rapid, uncontrolled eye movements

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.