Brotizolam: functions, dosage, side effects, how to use

What Drug Brotizolam?

What is brotizolam for?

Brotizolam is a benzodiazepine type drug that works to increase the effects of the chemical compound GABA to calm the central nervous system of the brain. The function of the drug brotizolam is to treat anxiety, acute alcohol withdrawal, and seizures. In addition, it is used to relieve muscle spasms and as an anesthetic before medical procedures.

OTHER USES: This section lists uses for this drug that are not listed on approved labels, but may be prescribed by your healthcare professional. Use this medication for the conditions listed below only if it has been prescribed by your doctor and health care professional.

Another function of brotizolam is to prevent extreme nightmares (terror at night).

How to use brotizolam?

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

Take this medication as directed by your doctor. The dosage is based on medical condition, age, and response to treatment. If you are using the liquid form of this medicine, use a special measuring device to measure the dose. Don't use a tablespoon as you may not get the right dose. If you are using a concentrated solution, use a dropper to measure the dose and mix it in a liquid or soft food (eg applesauce, pudding) before consumption.

Use this medication exactly as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed as this medicine can become addictive. Also, if it is used for a long period of time or to control seizures, do not discontinue use without a doctor's approval. Some conditions can get worse when the use of this drug is stopped suddenly. Your dose will need to be decreased slowly.

When used for a long period of time, this drug may not work very well and may require a different dosage. Talk with your doctor if this drug stops working.

The prohibition that must be done when taking brotizolam is to avoid eating fruit grapefruit or drink grapefruit juice unless the doctor instructs otherwise. Juice grapefruit increase the amount of certain drugs in the bloodstream. Consult your doctor or pharmacist for more details. Tell your doctor if your condition remains the same or gets worse.

How to store brotizolam?

The correct storage of the drug Brotizolam is stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Brotizolam dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the brotizolam dosage for adults?

The dosage for using brotizolam is as follows:

• Adults: 250 mcg per day at night before bed, up to 2 weeks.
• Elderly: 125 mcg before bed, up to 2 weeks.
• Maximum dose: 500 mcg.

What is the dose of brotizolam for children?

There is no provision for the dose of this drug for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use. Consult your doctor or pharmacist for more information.

Brotizolam side effects

What side effects can be experienced due to brotizolam?

Common side effects of using brotizolam are drowsiness, fatigue, constipation, and ataxia (loss of balance).

Seek immediate medical help if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Some of the conditions you should be aware of when taking brotizolam are:

• Confusion, hallucinations, unusual thoughts or behavior
• Unusual risk-taking behavior, not afraid of harm
• Depressed mood, thoughts of suicide or hurting yourself
• Hyperactivity, agitation, aggression
• The convulsions got worse
• Hard to breathe
• You feel like you might pass out
• Muscle twitching, tremors
• Loss of bladder control
• Urinating rarely or not at all

Less serious side effects include:

• Memory problems
• Drowsiness, feeling tired
• Dizziness, spinning sensation
• Feeling restless or irritated
• Muscle weakness
• Nausea, constipation
• Dry mouth, unclear speech
• Blurred, or double vision
• Mild skin rash, hives
• Decreased sex drive

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Brotizolam Drug Warnings and Cautions

What should be known before using brotizolam?

Before using Brotizolam:

• Tell your doctor and pharmacist if you are allergic to Brotizolam, alprazolam (Xanax), chlordiazepoxide (Librium, Librax), clonazepam (Klonopin), clorazepate (Tranxene), estazolam (ProSom), flurazepam (Dalmane), lorazepam (Ativan) Serax), prazepam (Centrax), temazepam (Restoril), triazolam (Halcion), or other drugs.
• Tell your doctor and pharmacist what prescription and nonprescription drugs you use, especially antihistamines: disulfiram (Antabuse); fluoxetine (Prozac); isoniazid (INH, Laniazid, Nydrazid); ketoconazole (Nizoral); levodopa (Larodopa, Sinemet); medications for depression, seizures, pain, Parkinson's disease, asthma, hay fever, or allergies; metoprolol (Lopressor, Toprol XL); muscle relaxant; family planning pills; probenecid (Benemid); propoxyphene (Darvon); propranolol (Inderal); ranitidine (Zantac); rifampin (Rifadin); sedatives; sleeping pills; theophylline (Theo-Dur); tranquilizers; valproic acid (Depakene); and vitamins. This medicine can increase the drowsiness caused by Brotizolam.
• If you are taking an antacid, use Brotizolam first then wait 1 hour before using an antacid.
• Tell your doctor if you have had or are suffering from glaucoma, seizures, or lung, heart, and liver disease.
• Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you find yourself pregnant while using Brotizolam, call your doctor right away.
• Talk with your doctor about the risks and benefits of using Brotizolam if you are 65 years or older. Seniors should not use Brotizolam as it is not as safe as other drugs that can be used to treat the same condition.
• If you are having surgery, including dental surgery, tell the doctor or dentist that you are using Brotizolam.
• You should know that this drug can make you drowsy. Do not drive a vehicle or operate machinery until you know how this drug affects you.
• Note that alcohol can add to the drowsiness caused by this drug.
• tell your doctor if you use tobacco products. Smoking can decrease the effectiveness of this drug.

Is brotizolam safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category D according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Research in breastfeeding women shows harmful effects on babies. You may want to prescribe another substitute for this medicine or you should stop breastfeeding while using this medicine.

Brotizolam Drug Interactions

What medicines may interact with brotizolam?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. While you are using this medication, it is very important for your doctor to know if you are taking any of the drugs from the following list. The following interactions are selected on the basis of their potential significance and are not necessarily all inclusive.

Using this medication with some of the medicines below is not usually recommended, but in some cases it may be necessary. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.

• Alfentanil
• Amobarbital
• Anileridine
• Aprobarbital
• Buprenorphine
• Butabarbital
• Butalbital
• Carbinoxamine
• Carisoprodol
• Chloral Hydrate
• Chlorzoxazone
• Cobicistat
• Codeine
• Dantrolene
• Eslicarbazepine Acetate
• Ethchlorvynol
• Etravirine
• Fentanyl
• Fosphenytoin
• Phospropofol
• Hydrocodone
• Hydromorphone
• Itraconazole
• Ketorolac
• Levorphanol
• Meclizine
• Meperidine
• Mephenesin
• Mephobarbital
• Meprobamate
• Metaxalone
• Methadone
• Methocarbamol
• Methohexital
• Mirtazapine
• Morphine
• Morphine Sulfate Liposome
• Orlistat
• Oxycodone
• Oxymorphone
• Pentobarbital
• Phenobarbital
• Phenytoin
• Primidone
• Propoxyphene
• Remifentanil
• Secobarbital
• Sodium Oxybate
• Sufentanil
• Suvorexant
• Tapentadol
• Thiopental
• Zolpidem

Taking this medication with the drugs below may increase your risk of side effects, but in some cases, a combination of these two drugs may be the best treatment. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.

• Amitriptyline
• Amprenavir
• Clarithromycin
• Dalfopristin
• Disulfiram
• Erythromycin
• Fluvoxamine
• Ginkgo
• Isoniazid
• Perampanel
• Quinupristin
• Rifapentine
• Roxithromycin
• St. John's Wort
• Theophylline
• Troleandomycin

Can food or alcohol interact with brotizolam?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with brotizolam?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• Have a history of alcohol abuse
• Have a history of substance abuse or dependence
• Respiratory problems or severe lung disease
• Glaucoma
• Severe liver disease
• Myasthenia gravis
• Apnea (pauses in breathing while sleeping) - should not be used in patients with this condition
• Have a history of depression - use with caution. Can make this condition worse
• Kidney illness
• Liver disease, mild to moderate - use with caution. The effect of the drug can be increased because the drug leaves the body slowly.

Brotizolam overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.