Etonogestrel: functions, dosage, side effects, how to use

What drug Etonogestrel?

What is etonogestrel for?

This medicine is used to prevent pregnancy. This medicine is in the form of a thin plastic stick about the size of a match that is inserted under the skin by a health care professional. The stem slowly releases etonogestrel into the body over the course of 3 years. Stems must be removed after 3 years and can be replaced if family planning is to be continued. The rods can be removed at any time by a trained healthcare professional if birth control is no longer desired or if there are side effects. The stem does not contain any estrogen. Etonogestrel (a form of progestin) is a hormone that prevents pregnancy by preventing the release of an egg (ovulation) and by changing the uterus and cervical mucus to make it difficult for the egg to meet with sperm (fertilization) or for a fertilized egg to attach to the uterine wall (implantation).

This drug may not work well in women who are very obese or those taking certain drugs. (See also the Drug Interactions section.) Discuss your birth control with your doctor.

Using this medicine does not protect you or your partner against sexually transmitted diseases (for example, HIV, gonorrhea).

How is etonogestrel used?

Read the patient information leaflet provided by your pharmacist or health care professional before inserting the rods. Read and sign the Approval Letter provided by your doctor. You will also be issued a User Card with the date and place on your body where the rod was inserted. Save the card and use it to remind yourself of the schedule for releasing the sticks. If you have questions, ask your doctor or pharmacist.

Ask your doctor about the best time to schedule your appointment after the rod is in place. Your doctor may want you to take a pregnancy test first. The medication usually starts working as soon as the stick is inserted on days 1 to 5 after the start of your usual menstrual bleeding. If your appointment is at another time in your menstrual cycle, you may need to use a non-hormonal form of birth control (eg, condom, diaphragm, spermicide) for the first 7 days after the rod is inserted. Ask your doctor about whether you need replacement birth control (birth control) kits.

The rod will be inserted into the skin on your upper arm. It will usually be placed on the arm opposite to the side of the arm you normally write on. Make sure you can feel the stem under your skin after it has been installed.

There will be 2 bandages covering the area where the rod is attached. Remove the top bandage for 24 hours. Leave the small bandage on for 3-5 days or as directed by your doctor. Keep the bandage clean and dry.

How is etonogestrel stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Etonogestrel dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the etonogestrel dosage for adults?

Normal Adult Dose for Contraception

An implant of 68 mg is inserted into the skin. Implants should not be left in place for more than three years.

The insertion time should be done according to the patient's history, as follows:

If there was no previous use of hormonal contraception in the past month, implants should be inserted between Day 1 and 5, (counting the first day of menstruation as “Day 1”), even if there is still bleeding.

If switching from combined hormonal contraceptives, implants can be inserted at any time within seven days after the last active (estrogen plus progestin) oral tablet contraceptive, any time during the NuvaRing seven-day free ring period (etonogestrel / ethinyl estradiol vaginal ring), or at any time. during the seven-day patch-free period of the transdermal contraceptive system.

If switching from a progestin-only method, implants should be inserted as follows: if switching only from the progestin-only pill, any time of the month (do not skip every day between the last insertions); if switching from a progestin-only implant, insert the implant the same day the contraceptive implant was removed; if switching from an IUD containing a progestin, insert the implant the same day the contraceptive implant was removed; if switching from a contraceptive injection, insert the implant on the day the next injection is due.

Here's the first trimester of abortion or miscarriage: the implant can be inserted as soon as the first trimester of the abortion. If it was not included within five days of first trimester abortion, follow directions without using hormonal contraception within the past month.

Postpartum or second trimester abortion: implants can be inserted between 21 to 28 days postpartum if not exclusively breastfeeding or between 21 to 28 days after the second trimester abortion. If more than four weeks have passed, the pregnancy must be excluded and the patient must use non-hormonal birth control methods for the first seven days after insertion. If the patient is exclusively breastfeeding, insert the implant after the fourth post-partum week.

What is the etonogestrel dosage for children?

Appropriate studies on the relationship of age to the effects of etonogestrel implants have not been carried out in the pediatric population. However, specific problems in children that would limit the usefulness of this drug in adolescents are not expected. This medicine can be used to control births in young women but should not be used before the onset of menstruation.

In what dosage is etonogestrel available?

Implanon

- Implant, subdermal 68 mg

Nexplanon

- Implant, subdermal 68 mg

Etonogestrel side effects

What side effects can be experienced due to etonogestrel?

Get emergency medical help if you have any of the following signs of an allergic reaction: hives; hard to breath; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• warmth, redness, swelling, or fluid flowing where the implant is inserted
• sudden numbness or weakness, especially on one side of the body
• severe pain or cramping in your pelvic area (maybe on only one side)
• sudden, severe headache, confusion, pain behind the eyes, problems with vision, ability to speak, or balance
• sudden cough, wheezing, rapid breathing, coughing up blood
• pain, swelling, warmth, or redness in one or both legs
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general feeling of pain
• breast lump
• swelling in your hands, ankles, or feet
• jaundice (yellowing of the skin or eyes)
• depressive symptoms (sleep problems, weakness, tired feeling, mood changes)
• dangerously high blood pressure (severe headache, blurred vision, ringing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeat, seizures).

Less serious side effects may include:

• pain, numbness, or tingling where the implant is inserted
• small bleeding or scar tissue where the implant was inserted
• menstrual cramps, changes in your menstrual periods
• lightheadedness, dizziness, mood changes
• vaginal itching or discharge
• breast pain
• acne
• problem with contact lenses
• nausea, mild stomach pain, back pain
• feeling nervous or depressed
• sore throat, flu symptoms
• weight gain

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Etonogestrel Drug Warnings and Cautions

What should be known before using etonogestrel?

Do not use etonogestrel implants if you are pregnant. If you have recently had a baby, wait at least 3 weeks (4 weeks if breastfeeding) before receiving etonogestrel implants.

You should not use these implants if you are allergic to etonogestrel, or if you have any of the following conditions: unusual vaginal bleeding, liver disease or liver cancer, or if you have had breast or uterine cancer, heart attack, stroke, or blood clots.

Before receiving etonogestrel implants, tell your doctor if you have diabetes, high blood pressure, high cholesterol, gallbladder disease, kidney disease, ovarian cysts, headaches, a history of depression, if you are overweight, or if you are allergic to medications. medicine.

Is etonogestrel safe for pregnant and lactating women?

Etonogestrel has not been formally classified for pregnancy by the FDA. Animal studies have been carried out on mice and rabbits, using up to 390 and 790 times the human dose, respectively (based on body surface) and have shown no harm to the fetus from etonogestrel exposure. Studies have shown no increased risk of birth defects in women who have used combined oral contraceptives before pregnancy or during early pregnancy. There is no evidence that the risks associated with etonogestrel differ from combined oral contraceptives. Etonogestrel is considered contraindicated during pregnancy. Etonogestrel implant must be removed if the pregnancy is to be sustained.

There are not sufficient studies in women to find out the risk to the baby when the mother takes this drug during breastfeeding. Consider the potential benefits and potential risks before taking this medication during breastfeeding.

Etonogestrel Drug Interactions

What medicines might interact with etonogestrel?

Although certain drugs should not be used together at all, in other cases two different drugs can be used together even if interactions are possible. In this case, your doctor may want to change the dose, or other precautions may be needed. When you are using this medicine it is very important that your healthcare professional knows if you are currently taking any of the medicines that are listed below. The following interactions were selected on the basis of their potential significance and are by no means applicable to all

Taking this drug with any of the following medicines is not recommended. Your doctor may not prescribe this drug to you or will replace some of the drugs you are already taking

• Tranexamic acid

Using this medication with some of the medicines below is not usually recommended, but in some cases it may be necessary. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them

• Aripiprazole
• Carbamazepine
• Dabrafenib
• Eliglustat
• Fentanyl
• Isotretinoin
• Theophylline

Using this medication with some of the medicines below is not usually recommended, but in some cases it may be necessary. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them

• Alprazolam
• Amprenavir
• Aprepitant
• Atazanavir
• Bacampicillin
• Betamethasone
• Bexarotene
• Bored
• Colesevelam
• Cyclosporine
• Darunavir
• Delavirdine
• Efavirenz
• Etravirine
• Fosamprenavir
• Fosaprepitant
• Fosphenytoin
• Griseofulvin
• Lamotrigine
• Licorice
• Modafinil
• Mycophenolate Mofetil
• Mycophenolic Acid
• Nelfinavir
• Oxcarbazepine
• Phenobarbital
• Phenytoin
• Pioglitazone
• Prednisolone
• Primidone
• Rifabutin
• Rifampin
• Rifapentine
• Ritonavir
• Rosuvastatin
• Rufinamide
• Selegiline
• St. John's Wort
• Telaprevir
• Topiramate
• Troglitazone
• Troleandomycin
• Voriconazole
• Warfarin

Can food or alcohol interact with etonogestrel?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider. The following interactions were selected on the basis of their potential significance and are by no means applicable to all.

Using this medication with any of the following may cause an increased risk of certain side effects, but they may not be avoided in some cases. When used together, your doctor may change the dose or how often you use these drugs, or give specific instructions about use of food, alcohol, or tobacco.

• Caffeine

What health conditions can interact with etonogestrel?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• abnormal or unusual vaginal bleeding (not menstruation)
• breast cancer, now or in the past or if suspected
• cancer (progestin-sensitive), history or current
• active liver disease
• liver tumor, benign or malignant - should not be used in patients with this condition
• blood clots, historical or current - should not be used in patients with blood clots in the brain, legs, lungs, eyes, or heart.
• a history of depression
• diabetes
• fluid retention (swollen body)
• gallbladder disease
• heart disease
• hypertension (high blood pressure)
• hyperlipidemia (high cholesterol or fat in the blood) - use with caution. It might make things worse.
• obesity - this condition can cause medications not to work properly

Etonogestrel overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.